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Autor:
Gareth J.S. Jenkins, John Beynon, A. Paul Griffiths, Dean A. Harris, Jeremy Williamson, Namor Williams, HG Jones, Rory Kokelaar
DNA hypermethylation in gene promoter regions (CpG islands) is emerging as an important pathway in colorectal cancer tumourigenesis. Whilst genetic mutations have been associated with extramural vascular invasion (EMVI) in rectal cancer, no such asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe88299363f4861bdb7e2403f82d567
https://europepmc.org/articles/PMC5790361/
https://europepmc.org/articles/PMC5790361/
Like many tumor suppressor genes, some miRNA genes harboring CpG islands undergo methylation-mediated silencing. In the study, we found significant downregulation and proximal promoter methylation of miR-203a and miR-203b in gastric cardia adenocarci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ef9b886566627f745927ca5ddcab3b