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Publikováno v:
Breast Cancer Research and Treatment
PurposeMenopause is associated with an increased risk of estrogen receptor-positive (ER +) breast cancer. To characterize the metabolic shifts associated with reduced estrogen bioavailability on breast tissue, metabolomics was performed from ovary-in
Autor:
Victoria L. Seewaldt, Mudaser Basam, Mark A. LaBarge, Jennifer C. Lopez, Arrianna Zirbes, Jesuchristopher Joseph, Rosalyn W. Sayaman
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia
Journal of mammary gland biology and neoplasia
Journal of mammary gland biology and neoplasia
A majority of breast cancers (BC) are age-related and we seek to determine what cellular and molecular changes occur in breast tissue with age that make women more susceptible to cancer initiation. Immune-epithelial cell interactions are important du
Autor:
J. Lévy, L. Zehnpfennig, Walter P. Weber, Elisabeth A. Kappos, Barbara Ling, Christian Kurzeder, Madleina Müller, Martin Haug, Savas D. Soysal, Mathilde Ritter, Ida Oberhauser, L. López Castrezana, Fabienne Schwab, Giacomo Montagna
Publikováno v:
Breast Cancer Research and Treatment
Purpose Some studies have indicated age-specific differences in quality of life (QoL) among breast cancer (BC) patients. The aim of this study was to compare patient-reported outcomes after conventional and oncoplastic breast surgery in two distinct
Autor:
Sixten Harborg, Marianne Ewertz, Deirdre Cronin-Fenton, Uffe Heide-Jørgensen, Thomas P. Ahern, Signe Borgquist
Publikováno v:
Breast Cancer Research and Treatment
Harborg, S, Heide-Jørgensen, U, Ahern, T P, Ewertz, M, Cronin-Fenton, D & Borgquist, S 2020, ' Statin use and breast cancer recurrence in postmenopausal women treated with adjuvant aromatase inhibitors : a Danish population-based cohort study ', Breast Cancer Research and Treatment, vol. 183, no. 1, pp. 153-160 . https://doi.org/10.1007/s10549-020-05749-5
Harborg, S, Heide-Jørgensen, U, Ahern, T P, Ewertz, M, Cronin-Fenton, D & Borgquist, S 2020, ' Statin use and breast cancer recurrence in postmenopausal women treated with adjuvant aromatase inhibitors : a Danish population-based cohort study ', Breast Cancer Research and Treatment, vol. 183, no. 1, pp. 153-160 . https://doi.org/10.1007/s10549-020-05749-5
Purpose To examine the association between statin use and risk of breast cancer recurrence in a national Danish cohort of postmenopausal breast cancer patients receiving aromatase inhibitors (AI) in the adjuvant setting. Patients and methods We enrol
Autor:
Gerhard Schoen, C Noebel, T Schroeder, Jan Felix Kuhne, Hannes Leischner, Paul Bittrich, Jens Fiehler, Susanne Gellißen, Julian I. Schroeder
Publikováno v:
Journal of Neuro-Oncology
Purpose Prior reports on the location and sizes of brain metastases almost entirely focus on patients with primary breast and pulmonary cancer. This is the first study comparing multiple other types of cancer that metastasize to the brain. Methods Th
Autor:
Allott, Emma, Shan, Yue, Chen, Mengjie, Sun, Xuezheng, Garcia-Recio, Susana, Kirk, Erin L, Olshan, Andrew F, Geradts, Joseph, Earp, H Shelton, Carey, Lisa A, Perou, Charles M, Pfeiffer, Ruth M, Anderson, William F., Troester, Melissa A.
Publikováno v:
Breast Cancer Research and Treatment
Allott, E, Shan, Y, Chen, M, Sun, X, Garcia-Recio, S, Kirk, E L, Olshan, A F, Geradts, J, Earp, H S, Earp, H S, Carey, L A, Perou, C M, Pfeiffer, R M, . Anderson, W F & Troester, M A 2019, ' Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications ', Breast Cancer Research and Treatment . https://doi.org/10.1007/s10549-019-05442-2
Allott, E, Shan, Y, Chen, M, Sun, X, Garcia-Recio, S, Kirk, E L, Olshan, A F, Geradts, J, Earp, H S, Earp, H S, Carey, L A, Perou, C M, Pfeiffer, R M, . Anderson, W F & Troester, M A 2019, ' Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications ', Breast Cancer Research and Treatment . https://doi.org/10.1007/s10549-019-05442-2
Purpose Female breast cancer demonstrates bimodal age frequency distribution patterns at diagnosis, interpretable as two main etiologic subtypes or groupings of tumors with shared risk factors. While RNA-based methods including PAM50 have identified
Publikováno v:
Breast Cancer Research and Treatment
Purpose Ductal carcinoma in situ (DCIS) is well-known precursor of invasive ductal carcinoma (IDC). Parts of patients show recurrence as DCIS or IDC after local treatment, but there are no established markers predicting relapse. We analyzed changes i
Publikováno v:
Breast Cancer Research and Treatment
Purpose The aim of this study was to determine if there were any differences in health-related outcomes and physical activity (PA) between the two OptiTrain exercise groups and usual care (UC), 2 years post-baseline. Methods The OptiTrain study was a
Autor:
Martti Arffman, Mikko Marttila, Esa Läärä, Elina Urpilainen, Ari Hautakoski, Ulla Puistola, Peeter Karihtala, Arja Jukkola, Reijo Sund, Mayu Hosio
Publikováno v:
Breast Cancer Research and Treatment
Purpose To address the possible association between the use of metformin, other forms of antidiabetic medication (ADM) and statins with the incidence of breast cancer in women with type 2 diabetes (T2D). Methods Data were collected from a Finnish nat
Autor:
Jesús Herranz, Miguel Martin, Philip S. Bernard, Amparo Ruiz, Michael J. Madsen, Álvaro Rodríguez-Lescure, Nicola J. Camp
Publikováno v:
Breast Cancer Research and Treatment
BREAST CANCER RESEARCH AND TREATMENT
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
BREAST CANCER RESEARCH AND TREATMENT
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
Background We recently showed PAM50 gene expression data can be represented by five quantitative, orthogonal, multi-gene breast tumor traits. These novel tumor ‘dimensions’ were superior to categorical intrinsic subtypes for clustering in high-ri