Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tilman Kühn"'
Publikováno v:
Der Diabetologe. 16:675-684
Die Ergebnisse experimenteller und epidemiologischer Studien deuten darauf hin, dass Diabetes die Risiken fur bestimmte gastrointestinale und gynakologische Tumoren erhoht. Am besten belegt ist dies hinsichtlich des Typ-2-Diabetes, wobei ahnliche Zus
Autor:
Vittorio Krogh, Rudolf Kaaks, Yvonne T. van der Schouw, Gianluca Severi, Eva Ardanaz, Marc J. Gunter, Tilman Kühn, Nicholas J. Wareham, Timothy J. Key, Francesca Mancini, Carlotta Sacerdote, María José Sánchez, Heiner Boeing, Annemieke M.W. Spijkerman, Peter M. Nilsson, Guy Fagherazzi, Miren Dorronsoro, María Dolores Chirlaque, Kay-Tee Khaw, Olov Rolandsson, Stephen J. Sharp, Salvatore Panico, Domenico Palli, Nita G. Forouhi, Christiane S. Hampe, Claudia Langenberg, Kim Overvad, Rosario Tumino, Elio Riboli
Publikováno v:
Rolandsson, O, Hampe, C S, Sharp, S J, Ardanaz, E, Boeing, H, Fagherazzi, G, Mancini, F R, Nilsson, P M, Overvad, K, Chirlaque, M-D, Dorronsoro, M, Gunter, M J, Kaaks, R, Key, T J, Khaw, K-T, Krogh, V, Kühn, T, Palli, D, Panico, S, Sacerdote, C, Sánchez, M-J, Severi, G, Spijkerman, A M W, Tumino, R, van der Schouw, Y T, Riboli, E, Forouhi, N G, Langenberg, C & Wareham, N J 2020, ' Autoimmunity plays a role in the onset of diabetes after 40 years of age ', Diabetologia, vol. 63, no. 2, pp. 266-277 . https://doi.org/10.1007/s00125-019-05016-3
Diabetologia
Diabetologia, Springer Verlag, 2020, 63 (2), pp.266-277. ⟨10.1007/s00125-019-05016-3⟩
Diabetologia, 63, 266. Springer Verlag
Diabetologia
Diabetologia, Springer Verlag, 2020, 63 (2), pp.266-277. ⟨10.1007/s00125-019-05016-3⟩
Diabetologia, 63, 266. Springer Verlag
Aims/hypothesis Type 1 and type 2 diabetes differ with respect to pathophysiological factors such as beta cell function, insulin resistance and phenotypic appearance, but there may be overlap between the two forms of diabetes. However, there are rela
Autor:
Charles M. Connolly, Deborah A. Nickerson, Jian Gong, Sébastien Küry, Barbara Pardini, Brent W. Zanke, Andrea Gsur, Jochen Hampe, Coral Arnau-Collell, M. Henar Alonso, Elio Riboli, Annika Lindblom, Ulrike Peters, Gad Rennert, Tabitha A. Harrison, Lori C. Sakoda, Caroline McNeil, Flavio Lejbkowicz, Hyun Min Kang, David J. Hunter, Martha L. Slattery, Miguel Rodríguez-Barranco, Christina Bamia, Satu Männistö, Timothy J. Key, W. James Gauderman, Gonçalo R. Abecasis, Sanford D. Markowitz, Laurence N. Kolonel, Mark A. Jenkins, Yi Lin, Robin Myte, Hedy S. Rennert, Neil Murphy, Antonia Trichopoulou, Christopher I. Li, Ross L. Prentice, Sai Chen, Stephanie J. Weinstein, Kristin E. Anderson, Hua Ling, Mitul Shah, Philipp Hofer, Wen Yi Huang, Sergi Castellví-Bel, Susanna C. Larsson, Maria Dolores Chirlaque, Wei Zheng, Stephanie L. Schmit, Cecelia A. Laurie, Soo-Chin Lee, David Forman, Andrea N. Burnett-Hartman, Giovanna Masala, Sarah C. Nelson, Michael O. Woods, Charles Kooperberg, Qing Zhang, Sonja I. Berndt, Christopher S. Carlson, Katja Butterbach, Hyeong Rok Kim, Rebecca D. Jackson, David Van Den Berg, Michael C. Bassik, Amanda J. Cross, Sushma S. Thomas, Clemens Schafmayer, Anna H. Wu, Douglas F. Easton, Robert W. Haile, Ludmila Vodickova, Graham G. Giles, Yu Ru Su, Jenny Chang-Claude, Lorena Moreno, Peter C. Scacheri, Stefanie Brezina, Min-Ho Shin, Steven Gallinger, Bethany Van Guelpen, Daniel D. Buchanan, Roger L. Milne, Stephen J. Chanock, Tin Louie, Tameka Shelford, Emily White, Kala Visvanathan, Loic Le Marchand, Veronika Vymetalkova, Roxann G. Ingersoll, Temitope O. Keku, Stephanie A. Bien, Fredrick R. Schumacher, Wan-Ling Hsu, Amanda E. Toland, John S. Grove, Noralane M. Lindor, Faye Elliott, Leon Raskin, Heather Hampel, Joshua D. Smith, Vicente Martín, David V. Conti, Sjoerd G. Elias, Henk J. van Kranen, Manish Gala, Daniela Seminara, Syed H.E. Zaidi, Suzanne M. Leal, Tilman Kühn, Korbinian Weigl, Marc J. Gunter, Cornelia M. Ulrich, Peyton Greenside, Victor Moreno, John D. Potter, Michael Hoffmeister, Eric J. Jacobs, Catherine M. Tangen, Jihyoun Jeon, Fränzel J.B. Van Duijnhoven, Andrew T. Chan, Stephen B. Gruber, John A. Baron, Alicja Wolk, Edith J. M. Feskens, Demetrius Albanes, Amit Joshi, Bette J. Caan, Polly A. Newcomb, Stéphane Bézieau, Elizabeth M. Gillanders, Anshul Kundaje, Elizabeth A. Platz, Michael Wainberg, Sun-Seog Kweon, C. Roland Wolf, Gemma Ibáñez-Sanz, Shuji Ogino, Emiko Kobayashi, Richard B. Hayes, Patrick S. Parfrey, Katarina Cuk, Stephen N. Thibodeau, Kenneth Offit, David Duggan, Sophia Harlid, Pavel Vodicka, Juergen Boehm, Christa Stegmaier, Jeroen R. Huyghe, Joseph Vijai, Sang-Hee Cho, Elizabeth W. Pugh, Rachel Pearlman, Alessio Naccarati, Marilena Melas, Graham Casey, Jane Romm, Stephan Buch, Phyllis J. Goodman, Albert de la Chapelle, John L. Hopper, Zsofia K. Stadler, Corinne E. Joshu, Liesel M. FitzGerald, Wolfgang Lieb, Aung Ko Win, Keith R. Curtis, Hermann Brenner, Christopher K. Edlund, Li Hsu, Conghui Qu, Peter T. Campbell, Robert E. Schoen, Heiner Boeing, D. Timothy Bishop, Kimberly F. Doheny, Sabina Sieri, Barbara L. Banbury, Mathieu Lemire, Jane C. Figueiredo, Gregory Idos, Katerina Shulman, Thomas J. Hudson, Melissa C. Southey, Duncan C. Thomas, Paul D.P. Pharoah, Mila Pinchev, Vittorio Perduca, Rocky Fischer, Volker Arndt, William M. Grady, Nasa Sinnott-Armstrong, N. Charlotte Onland-Moret, David M. Levine, Li Li, Dallas R. English
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Nature genetics
Nature Genetics, 51, 76-87
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩
Nature Genetics, 51(1), 76. Nature Publishing Group
Nature Genetics 51 (2018)
Universidad de Barcelona
Nature genetics
Nature Genetics, 51, 76-87
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩
Nature Genetics, 51(1), 76. Nature Publishing Group
Nature Genetics 51 (2018)
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide asso
Autor:
Renée T. Fortner, Charlotte Le Cornet, Theron Johnson, Tilman Kühn, Rudolf Kaaks, Britta Walter, Ester Herpel, Disorn Sookthai
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-10 (2020)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background Experimental and epidemiological studies demonstrate a role for 27-hydroxycholesterol (27HC) in breast cancer development, though results are conflicting. Cholesterol 27-hydroxylase (CYP27A1) and oxysterol 7-alpha-hydroxylase (CYP7B1) regu
Autor:
Rudolf Kaaks, Heinz Freisling, Mirja E. Graf, Verena Katzke, Tilman Kühn, Disorn Sookthai, Ruth Schübel, Theron Johnson
Publikováno v:
British Journal of Cancer
Background: It has long been proposed that albumin, bilirubin and uric acid may inhibit cancer development due to their anti-oxidative properties. However, there is a lack of population-based studies on blood levels of these molecules and cancer risk
Autor:
Antonia Trichopoulou, Jenny Chang-Claude, Deborah A. Nickerson, Yu Ru Su, Michael Hoffmeister, Andrew T. Chan, David V. Conti, Stephen B. Gruber, Li Li, Loic Le Marchand, Annika Lindblom, Jochen Hampe, Graham G. Giles, Graham Casey, Clemens Schafmayer, Tabitha A. Harrison, Gianluca Severi, Peter C. Scacheri, Tilman Kühn, Rosario Tumino, Vicente Martín, Elio Riboli, Hermann Brenner, Stephanie A. Bien, Chenxu Qu, Douglas F. Easton, Hyun Min Kang, Núria Sala, Ulrike Peters, Emily White, Peter T. Campbell, Christopher S. Carlson, Daniel D. Buchanan, Ellen Kampman, Sai Chen, Kenneth Offit, Barbara L. Banbury, Gad Rennert, Steven Gallinger, Noralane M. Lindor, Xingyi Guo, John D. Potter, Edith J.M. Feskens, Mark A. Jenkins, Marc J. Gunter, Joshua D. Smith, Eric J. Jacobs, Jeroen R. Huyghe, Anna H. Wu, Yingchang Lu, Charles M. Connolly, Stephanie J. Weinstein, Sébastien Küry, Bette J. Caan, Cornelia M. Ulrich, Christopher I. Li, Stephanie L. Schmit, Paul L. Auer, Paul D.P. Pharaoh, Stéphane Bezieau, Victor Moreno, Sonja I. Berndt, Caroline McNeil, Flavio Lejbkowicz, Demetrius Albanes, Michael O. Woods, RL Milne, Polly A. Newcomb, Fränzel J. B. van Duijnhoven, Thomas J. Hudson, Martha L. Slattery, Gonçalo R. Abecasis, Marilena Melas, Conghui Qu, Alicja Wolk, Li Hsu, Bethany Van Guelpen, Wei Zheng
Publikováno v:
Bien, S A, Su, Y R, Conti, D V, Harrison, T A, Qu, C, Guo, X, Lu, Y, Albanes, D, Auer, P L, Banbury, B L, Berndt, S I, Bézieau, S, Brenner, H, Buchanan, D D, Caan, B J, Campbell, P T, Carlson, C S, Chan, A T, Chang-Claude, J, Chen, S, Connolly, C M, Easton, D F, Feskens, E J M, Gallinger, S, Giles, G G, Gunter, M J, Hampe, J, Huyghe, J R, Hoffmeister, M, Hudson, T J, Jacobs, E J, Jenkins, M A, Kampman, E, Kang, H M, Kühn, T, Küry, S, Lejbkowicz, F, Le Marchand, L, Milne, R L, Li, L, Li, C I, Lindblom, A, Lindor, N M, Martín, V, McNeil, C E, Melas, M, Moreno, V, Newcomb, P A, Offit, K, Pharaoh, P D P, Potter, J D, Qu, C, Riboli, E, Rennert, G, Sala, N, Schafmayer, C, Scacheri, P C, Schmit, S L, Severi, G, Slattery, M L, Smith, J D, Trichopoulou, A, Tumino, R, Ulrich, C M, van Duijnhoven, F J B, Van Guelpen, B, Weinstein, S J, White, E, Wolk, A, Woods, M O, Wu, A H, Abecasis, G R, Casey, G, Nickerson, D A, Gruber, S B, Hsu, L, Zheng, W & Peters, U 2019, ' Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer ', Human Genetics, vol. 138, no. 4, pp. 307-326 . https://doi.org/10.1007/s00439-019-01989-8
Human Genetics, 138, 4, pp. 307-326
Human Genetics, 138, 307-326
Dipòsit Digital de la UB
Universidad de Barcelona
Human Genetics, 138(4), 307-326
Human Genetics
Human Genetics 138 (2019) 4
Human Genetics, 138, 4, pp. 307-326
Human Genetics, 138, 307-326
Dipòsit Digital de la UB
Universidad de Barcelona
Human Genetics, 138(4), 307-326
Human Genetics
Human Genetics 138 (2019) 4
Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to exert their effects by modulating gene expression. The computational method PrediXcan uses c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d5ff8b46c0a2417827ebad910f777c
https://www.repository.cam.ac.uk/handle/1810/290950
https://www.repository.cam.ac.uk/handle/1810/290950
Autor:
Myrto Barrdahl, Anika Hüsing, Rudolf Kaaks, Heiner Boeing, Annika Steffen, Matthias B. Schulze, Tilman Kühn, Verena Katzke, Jasmine Neamat-Allah, Ursula Bachlechner
Publikováno v:
Diabetologia. 58:2718-2725
Studies on weight cycling and the risk of type 2 diabetes have revealed inconsistent results, possibly due to differences in the definition of weight fluctuations. Here, we investigated whether weight cycling during adulthood is related to diabetes r
Publikováno v:
Katzke, V A, Sookthai, D, Johnson, T, Kuhn, T & Kaaks, R 2017, ' Blood lipids and lipoproteins in relation to incidence and mortality risks for CVD and cancer in the prospective EPIC-Heidelberg cohort ', BMC Medicine, vol. 15, no. 1, pp. 218 . https://doi.org/10.1186/s12916-017-0976-4
BMC Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
BMC Medicine
BMC Medicine, Vol 15, Iss 1, Pp 1-13 (2017)
BMC Medicine
Background Circulating concentrations of lipid biomarkers are associated with risk of cardiovascular diseases (CVD). The evidence for a relationship with cancer risk, however, is not entirely consistent. This study aims to assess the relationships of
Autor:
Tilman Kühn, Jasmine Neamat-Allah, Rudolf Kaaks, Birgit Teucher, Verena Katzke, Anika Hüsing, Stefan Delorme, Diana Nabers, Theron Johnson
Publikováno v:
European Journal of Nutrition. 54:701-708
To investigate whether blood-based biomarkers can improve the prediction of visceral fat volume as measured by magnetic resonance imaging (MRI) and thus be used as proxies of visceral adiposity in large-scale epidemiological studies. Whole-body MRI w
Autor:
Tilman Kühn
Publikováno v:
Current Nutrition Reports. 3:94-101
The early observation of a low prevalence of coronary heart disease and a high prevalence of hemorrhagic stroke in Inuit populations was attributed to a high habitual intake of seafood and marine-derived n-3 fatty acids leading to reduced platelet ag