Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Richard A, Koup"'
Autor:
Ahmed S. Fahad, Cheng Yu Chung, Sheila N. López Acevedo, Nicoleen Boyle, Bharat Madan, Matías F. Gutiérrez-González, Rodrigo Matus-Nicodemos, Amy D. Laflin, Rukmini R. Ladi, John Zhou, Jacy Wolfe, Sian Llewellyn-Lacey, Richard A. Koup, Daniel C. Douek, Henry H. Balfour, David A. Price, Brandon J. DeKosky
Publikováno v:
Scientific Reports. 13
Adoptive immune therapies based on the transfer of antigen-specific T cells have been used successfully to treat various cancers and viral infections, but improved techniques are needed to identify optimally protective human T cell receptors (TCRs).
Autor:
Suzanne M. Scheaffer, Diana Lee, Bradley Whitener, Baoling Ying, Kai Wu, Chieh-Yu Liang, Hardik Jani, Philippa Martin, Nicholas J. Amato, Laura E. Avena, Daniela Montes Berrueta, Stephen D. Schmidt, Sijy O’Dell, Arshan Nasir, Gwo-Yu Chuang, Guillaume Stewart-Jones, Richard A. Koup, Nicole A. Doria-Rose, Andrea Carfi, Sayda M. Elbashir, Larissa B. Thackray, Darin K. Edwards, Michael S. Diamond
Publikováno v:
Nature Medicine. 29:247-257
Autor:
Noemia S. Lima, Maryam Musayev, Timothy S. Johnston, Danielle A. Wagner, Amy R. Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P. Black, Sijy O’Dell, Stephen D. Schmidt, Damee Moon, Cynthia G. Lorang, Bingchun Zhao, Man Chen, Kristin L. Boswell, Jesmine Roberts-Torres, Rachel L. Davis, Lowrey Peyton, Sandeep R. Narpala, Sarah O’Connell, Leonid Serebryannyy, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Geoffrey Shimberg, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J. Ruckwardt, Amarendra Pegu, John Misasi, Nicole A. Doria-Rose, Martin Gaudinski, Richard A. Koup, Peter D. Kwong, Adrian B. McDermott, Sharon Amit, Timothy W. Schacker, Itzchak Levy, John R. Mascola, Nancy J. Sullivan, Chaim A. Schramm, Daniel C. Douek
Publikováno v:
Nature Communications. 13
An important consequence of infection with a SARS-CoV-2 variant is protective humoral immunity against other variants. However, the basis for such cross-protection at the molecular level is incompletely understood. Here, we characterized the repertoi
Autor:
Robert Parks, Kelly E. Seaton, Barton F. Haynes, Jim Tartaglia, Jeffrey Tomalka, Muhammad Bilal Latif, Georgia D. Tomaras, Slim Fourati, Ana María González, Adam Pelletier, Nelson L. Michael, Richard A. Koup, Rafick Pierre Sekaly, Peter Wilkinson, Genoveffa Franchini, Merlin L. Robb, Norman L. Letvin, Kathryn Furr, Sampa Santra, Michelle A. Lifton, Nicole L. Yates, Ashish Sharma, Kevin R. Carlson
Publikováno v:
Nature Immunology. 22:1294-1305
Development of effective human immunodeficiency virus 1 (HIV-1) vaccines requires synergy between innate and adaptive immune cells. Here we show that induction of the transcription factor CREB1 and its target genes by the recombinant canarypox vector
Autor:
Thomas Calder, Tina Tong, Dale J. Hu, Jerome H. Kim, Karen L. Kotloff, Richard A. Koup, Mary A. Marovich, M. Juliana McElrath, Sarah W. Read, Merlin L. Robb, Philip O. Renzullo, M. Patricia D’Souza
Publikováno v:
Communications Medicine. 2
The rapid development of COVID-19 vaccines and their deployment in less than a year is an unprecedented scientific, medical, and public health achievement. This rapid development leveraged knowledge from decades of HIV/AIDS research and advances. How
Autor:
Marciela M. DeGrace, Elodie Ghedin, Matthew B. Frieman, Florian Krammer, Alba Grifoni, Arghavan Alisoltani, Galit Alter, Rama R. Amara, Ralph S. Baric, Dan H. Barouch, Jesse D. Bloom, Louis-Marie Bloyet, Gaston Bonenfant, Adrianus C. M. Boon, Eli A. Boritz, Debbie L. Bratt, Traci L. Bricker, Liliana Brown, William J. Buchser, Juan Manuel Carreño, Liel Cohen-Lavi, Tamarand L. Darling, Meredith E. Davis-Gardner, Bethany L. Dearlove, Han Di, Meike Dittmann, Nicole A. Doria-Rose, Daniel C. Douek, Christian Drosten, Venkata-Viswanadh Edara, Ali Ellebedy, Thomas P. Fabrizio, Guido Ferrari, Will M. Fischer, William C. Florence, Ron A. M. Fouchier, John Franks, Adolfo García-Sastre, Adam Godzik, Ana Silvia Gonzalez-Reiche, Aubree Gordon, Bart L. Haagmans, Peter J. Halfmann, David D. Ho, Michael R. Holbrook, Yaoxing Huang, Sarah L. James, Lukasz Jaroszewski, Trushar Jeevan, Robert M. Johnson, Terry C. Jones, Astha Joshi, Yoshihiro Kawaoka, Lisa Kercher, Marion P. G. Koopmans, Bette Korber, Eilay Koren, Richard A. Koup, Eric B. LeGresley, Jacob E. Lemieux, Mariel J. Liebeskind, Zhuoming Liu, Brandi Livingston, James P. Logue, Yang Luo, Adrian B. McDermott, Margaret J. McElrath, Victoria A. Meliopoulos, Vineet D. Menachery, David C. Montefiori, Barbara Mühlemann, Vincent J. Munster, Jenny E. Munt, Manoj S. Nair, Antonia Netzl, Anna M. Niewiadomska, Sijy O’Dell, Andrew Pekosz, Stanley Perlman, Marjorie C. Pontelli, Barry Rockx, Morgane Rolland, Paul W. Rothlauf, Sinai Sacharen, Richard H. Scheuermann, Stephen D. Schmidt, Michael Schotsaert, Stacey Schultz-Cherry, Robert A. Seder, Mayya Sedova, Alessandro Sette, Reed S. Shabman, Xiaoying Shen, Pei-Yong Shi, Maulik Shukla, Viviana Simon, Spencer Stumpf, Nancy J. Sullivan, Larissa B. Thackray, James Theiler, Paul G. Thomas, Sanja Trifkovic, Sina Türeli, Samuel A. Turner, Maria A. Vakaki, Harm van Bakel, Laura A. VanBlargan, Leah R. Vincent, Zachary S. Wallace, Li Wang, Maple Wang, Pengfei Wang, Wei Wang, Scott C. Weaver, Richard J. Webby, Carol D. Weiss, David E. Wentworth, Stuart M. Weston, Sean P. J. Whelan, Bradley M. Whitener, Samuel H. Wilks, Xuping Xie, Baoling Ying, Hyejin Yoon, Bin Zhou, Tomer Hertz, Derek J. Smith, Michael S. Diamond, Diane J. Post, Mehul S. Suthar
Publikováno v:
Nature
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants jeopardizes the protective antiviral immunity induced following infection or vaccination. To address the public health threat caused by the increasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e896e07b5a30bbcb962870bf7aaa91b
https://www.repository.cam.ac.uk/handle/1810/335637
https://www.repository.cam.ac.uk/handle/1810/335637
Autor:
Richard A. Koup, Ruben O. Donis, Peter B. Gilbert, Andrew W. Li, Najaf A. Shah, Christopher R. Houchens
Publikováno v:
Nature Medicine. 28:214-214
Autor:
Mary E. Enama, Sarah F. Andrews, Julie E. Ledgerwood, Richard A. Koup, Richard M. Schwartz, Adam DeZure, Sarah H. Plummer, Galina Yamshchikov, Ingelise J. Gordon, Emily E. Coates, Michelle C. Crank, John R. Mascola, Terrence M. Tumpey, Xiangjie Sun, Barney S. Graham, Kathryn L Zephir, Adrian B. McDermott, Zonghui Hu, Florence Kaltovich, Robert T. Bailer
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-6 (2017)
NPJ Vaccines
npj Vaccines
NPJ Vaccines
npj Vaccines
A novel avian influenza subtype, A/H7N9, emerged in 2013 and represents a public health threat with pandemic potential. We have previously shown that DNA vaccine priming increases the magnitude and quality of antibody responses to H5N1 monovalent ina
Autor:
Srinivas S. Rao, Jason Hataye, Keyun Wang, Joseph P. Casazza, Tongqing Zhou, Lan Wu, Zhi Yong Yang, Amarendra Pegu, Wei Shi, Richard A. Koup, John Paul Todd, Peter D. Kwong, Gary J. Nabel, Ivelin S. Georgiev, Xiaoti Guo, Xuejun Chen, Mangaiarkarasi Asokan, Sijy O'Dell, John R. Mascola
Publikováno v:
Nature Communications
The treatment of AIDS with combination antiretroviral therapy (cART) remains lifelong largely because the virus persists in latent reservoirs. Elimination of latently infected cells could therefore reduce treatment duration and facilitate immune reco