Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karel Souček"'
Autor:
Hana Kotasová, Michaela Capandová, Vendula Pelková, Jana Dumková, Zuzana Koledová, Ján Remšík, Karel Souček, Zuzana Garlíková, Veronika Sedláková, Anas Rabata, Petr Vaňhara, Lukáš Moráň, Lukáš Pečinka, Volodymyr Porokh, Martin Kučírek, Libor Streit, Josef Havel, Aleš Hampl
Publikováno v:
Tissue Eng Regen Med
BACKGROUND: The progenitors to lung airway epithelium that are capable of long-term propagation may represent an attractive source of cells for cell-based therapies, disease modeling, toxicity testing, and others. Principally, there are two main opti
Publikováno v:
Scientific Reports. 13
The distribution of fluorescence signals measured with flow cytometry can be influenced by several factors, including qualitative and quantitative properties of the used fluorochromes, optical properties of the detection system, as well as the variab
Autor:
Sára Lenárt, Peter Lenárt, Lucia Knopfová, Hana Kotasová, Vendula Pelková, Veronika Sedláková, Ondřej Vacek, Jana Pokludová, Vladimír Čan, Jan Šmarda, Karel Souček, Aleš Hampl, Petr Beneš
Publikováno v:
Lenárt, Sára; Lenárt, Peter; Knopfová, Lucia; Kotasová, Hana; Pelková, Vendula; Sedláková, Veronika; Vacek, Ondřej; Pokludová, Jana; Čan, Vladimír; Šmarda, Jan; Souček, Karel; Hampl, Aleš; Beneš, Petr (2022). TACSTD2 upregulation is an early reaction to lung infection. Scientific reports, 12(1), p. 9583. Springer Nature 10.1038/s41598-022-13637-9
TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody–drug conjugate targeting Trop2 were recently approved for cancer therapy, the physiol
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The epithelial-mesenchymal plasticity, in tight association with stemness, contributes to the mammary gland homeostasis, evolution of early neoplastic lesions and cancer dissemination. Focused on cell surfaceome, we used mouse models of pre-neoplasti
Autor:
Zuzana Kahounová, Petr Beneš, Ján Remšík, Jiřina Procházková, Jan Bouchal, Tereza Suchankova, Gvantsa Kharaishvili, Karel Souček, Milan Král, Radek Fedr, Eva Slabáková, Šárka Šimečková
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Skp2 is a crucial component of SCFSkp2 E3 ubiquitin ligase and is often overexpressed in various types of cancer, including prostate cancer (PCa). The epithelial-to-mesenchymal transition (EMT) is involved in PCa progression. The acquisition of a mes
Publikováno v:
Cell Death & Disease. 9
The PDF and HTML versions of the article have been updated to include the Creative Commons Attribution 4.0 International License information.
Autor:
Jaromír Mikeš, Rastislav Jendželovský, Peter Fedoročko, Jiřina Procházková, Ján Koval, Karel Souček, Jiřina Hofmanová, Veronika Sačková, Alois Kozubík, Martin Kello
Publikováno v:
Photochemical & Photobiological Sciences. 8:1716-1723
Photodynamic therapy (PDT) is a flexible multi-target therapeutic approach. One of the main requirements of successful PDT is sufficient intracellular concentration of an applicable photosensitizer. Mechanisms of anticancer drug elimination by tumour
Publikováno v:
Cellular and Molecular Life Sciences. 60:2736-2748
c-Fos and v-Fos belong to a group of proteins forming the transcription factor AP-1 that is important for regulation of proliferation, differentiation and programmed cell death in multiple cell types. In this study, we examined the role of c-Fos and
Autor:
Milan Král, Gvantsa Kharaishvili, Josef Jaroš, Šárka Šimečková, Alois Kozubík, Radek Fedr, Jan Bouchal, Tereza Suchankova, Karel Souček, Zuzana Pernicová, Eva Slabáková
Publikováno v:
Molecular Cancer
Background Tumor heterogeneity and the plasticity of cancer cells present challenges for effective clinical diagnosis and therapy. Such challenges are epitomized by neuroendocrine transdifferentiation (NED) and the emergence of neuroendocrine-like ca