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pro vyhledávání: '"Joseph Bass"'
Autor:
Nina C. Lund, Yetunde Kayode, Melanie R. McReynolds, Deanna C. Clemmer, Hannah Hudson, Isabelle Clerc, Hee-Kyung Hong, Jason M. Brenchley, Joseph Bass, Richard T. D’Aquila, Harry E. Taylor
Publikováno v:
Communications Biology. 5
Translocated lipopolysaccharide (LPS) activates monocytes via TLR4 and is hypothesized to increase cardiovascular disease risk in persons living with HIV. We tested whether mTOR activity supports LPS-stimulated monocyte production of pro-inflammatory
Autor:
Raj Awatramani, Daniel C. Levine, Biliana Marcheva, Xiaozhong Wang, Nathan Waldeck, Mohamad Mokadem, Joseph S. Takahashi, Joseph Bass, Ravindra Dhir, Clara Bien Peek, Wenyu Huang, Rexford S. Ahima, Yumiko Kobayashi, Lei Cheng, Jonathan Cedernaes, Kathryn Moynihan Ramsey, Chiaki Omura, Christopher A. Bradfield
Publikováno v:
Cell Metab
The alignment of fasting and feeding with the sleep/ wake cycle is coordinated by hypothalamic neurons, though the underlying molecular programs remain incompletely understood. Here, we demonstrate that the clock transcription pathway maximizes eatin
Autor:
Joseph Bass
Publikováno v:
Nature Medicine. 19:1090-1092
The fibroblast growth factor 21 (FGF21)-β-Klotho pathway orchestrates a switch to oxidative metabolism during fasting and starvation and has been implicated as a signal connecting nutrition, growth, reproduction and longevity. Two new studies in mic
Autor:
Joseph Bass, Joseph S. Takahashi
Publikováno v:
Nature. 469:476-478
Oscillations in gene transcription that occur in response to biological daily clocks coordinate the physiological workings of living organisms. But turnover in cellular energy may be sufficient to make the clock tick. See Article p.498 & Letter p.554
Autor:
Joseph Bass
Publikováno v:
Nature Medicine. 16:1074-1076
Just as a Bob Marley tune can elicit a visceral pull, a rhythmic awakening can shake up metabolism, with a new study in mice showing that cryptochrome (CRY) in the liver controls glucose levels during fasting and improves insulin sensitivity—introd
Autor:
Seong Hun Kim, Stephen C. Meredith, Sangram S. Sisodia, Rong Wang, Donald F. Steiner, Joseph Bass, David G. Lynn, Gopal Thinakaran, David Gordon
Publikováno v:
Nature Neuroscience. 2:984-988
The genetic lesion underlying familial British dementia (FBD), an autosomal dominant neurodegenerative disorder, is a T-A transversion at the termination codon of the BRI gene. The mutant gene encodes BRI-L, the precursor of ABri peptides that accumu
Autor:
Joseph Bass
Publikováno v:
Nature Digest. 9:24-25
Autor:
Joseph Bass
Publikováno v:
Nature. 485:45-46
A biological clock synchronizes animal behaviour and physiology with Earth's 24-hour rotation. Drugs targeting the clock's 'gears' show promise for treating obesity and other metabolic disorders. See Article p.62 & Letter p.123 Metabolic processes ne