Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jon-Kar Zubieta"'
Autor:
Tiffany Love, Andrey A. Shabalin, Rachel L. Kember, Anna R. Docherty, Hang Zhou, Vincent Koppelmans, Joel Gelernter, Anne K. Baker, Emily Hartwell, Jacob Dubroff, Jon-Kar Zubieta, Henry R. Kranzler
Publikováno v:
Neuropsychopharmacology. 47:1784-1790
Autor:
Christian S. Stohler, Phillip L. Campbell, Robert Dantzer, Alan R. Prossin, Jon Kar Zubieta, Alisa E. Koch, Geoffroy Laumet
Publikováno v:
Molecular Psychiatry. 27:831-839
Behavioral conditioning and expectation can have profound impact on animal and human physiology. Placebo, administered under positive expectation in clinical trials, can have potent effects on disease pathology, obscuring active medications. Emerging
Autor:
Javier Ballester, Anne K. Baker, Ilkka K. Martikainen, Vincent Koppelmans, Jon-Kar Zubieta, Tiffany M. Love
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)
Translational Psychiatry, Vol 12, Iss 1, Pp 1-7 (2022)
µ-Opioid receptors (MOR) are a major target of endogenous and exogenous opioids, including opioid pain medications. The µ-opioid neurotransmitter system is heavily implicated in the pathophysiology of chronic pain and opioid use disorder and, as su
Autor:
Keith G Jones, Kendal A. Walker, Mike Angstadt, Margit Burmeister, Brian J. Mickey, David Goldman, Robert C. Welsh, Katherine G. Warthen, Chandra Sripada, Benjamin Sanford, Jon Kar Zubieta
Publikováno v:
Neuropsychopharmacology. 44:495-502
Neuropeptide Y (NPY) produces anxiolytic effects in rodent models, and naturally occurring low NPY expression in humans has been associated with negative emotional phenotypes. Studies in rodent models have also demonstrated that NPY elicits reward be
Autor:
Marta Peciña, Jordan F. Karp, Mark S. Todtenkopf, Jon Kar Zubieta, Sanjay J. Mathew, Elliot Ehrich
Publikováno v:
Molecular psychiatry
The United States is in the midst of an opioid addiction and overdose crisis precipitated and exacerbated by use of prescription opioid medicines. The majority of opioid prescriptions are dispensed to patients with comorbid mood disorders including m
Autor:
Tiffany M. Love, Joseph Heffernan, Brian J. Mickey, Curtis J Heisel, Jon Kar Zubieta, Marta Peciña, David T. Hsu
Publikováno v:
Psychopharmacology. 233:3905-3919
Oxytocin is a neuropeptide widely recognized for its role in regulating social and reproductive behavior. Increasing evidence from animal models suggests that oxytocin also modulates reward circuitry in non-social contexts, but evidence in humans is
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-11 (2018)
Translational Psychiatry
Translational Psychiatry
Placebo responses in depression exemplify how expectancies and appraisals impact mood. Cognitive and neural mechanisms underlying these responses are still poorly understood, partly due to the difficulty of simulating antidepressant effects and manip
Autor:
Brian J. Mickey, Kortni K. Meyers, Sara J. Walker, Tiffany M. Love, Kathleen E. Hazlett, Scott A. Langenecker, David T. Hsu, Robert A. Koeppe, Benjamin Sanford, Jon Kar Zubieta
Publikováno v:
Molecular Psychiatry. 20:193-200
The μ-opioid receptor (MOR) system, well known for dampening physical pain, is also hypothesized to dampen 'social pain.' We used positron emission tomography scanning with the selective MOR radioligand [(11)C]carfentanil to test the hypothesis that
Autor:
Marta Peciña, Jon Kar Zubieta
Publikováno v:
Molecular psychiatry
Endogenous opioid and non-opioid mechanisms (for example, dopamine (DA), endocannabinoids (eCB)) have been implicated in the formation of placebo analgesic effects, with initial reports dating back three decades. Besides the perspective that placebo
Autor:
Alisa E. Koch, Mary M. Heitzeg, Alan R. Prossin, Christian S. Stohler, K. Luan Phan, Jon-Kar Zubieta, Phillip L. Campbell, Steven S. Zalcman
Publikováno v:
Neuropsychopharmacology. 40:554-565
Evidence in animal models suggests IL-1 family cytokines interact with central endogenous opioid neurotransmitter systems, inducing or perpetuating pathological states such as persistent pain syndromes, depression, substance use disorders, and their