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pro vyhledávání: '"Jeffrey E. DeClue"'
Publikováno v:
Oncogene. 15:1611-1616
Several inherited predisposition to cancer syndromes are associated with the development of nervous system tumors. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder in which affected individuals are at risk for developing astrocytoma
Autor:
Jeffrey E. DeClue, Ke Zhang, William C. Vass, Alex G. Papageorge, Frank McCormick, Douglas R. Lowy
Publikováno v:
Nature. 346:754-756
The ras genes are required for normal cell growth and mediate transformation by oncogenes encoding protein tyrosine kinases. Normal ras can transform cells in vitro and in vivo, but mutationally activated ras does so much more efficiently, and highly
Publikováno v:
Nature Genetics. 27:81-81