Zobrazeno 1 - 10
of 14
pro vyhledávání: '"James A. Wohlschlegel"'
Autor:
Joselyn S. Soto, Yasaman Jami-Alahmadi, Jakelyn Chacon, Stefanie L. Moye, Blanca Diaz-Castro, James A. Wohlschlegel, Baljit S. Khakh
Publikováno v:
Nature. 616:764-773
Astrocytes and neurons extensively interact in the brain. Identifying astrocyte and neuron proteomes is essential for elucidating the protein networks that dictate their respective contributions to physiology and disease. Here we used cell-specific a
Autor:
Kevin Qian, Marcus J. Tol, Jin Wu, Lauren F. Uchiyama, Xu Xiao, Liujuan Cui, Alexander H. Bedard, Thomas A. Weston, Pradeep S. Rajendran, Laurent Vergnes, Yuta Shimanaka, Yesheng Yin, Yasaman Jami-Alahmadi, Whitaker Cohn, Bryce T. Bajar, Chia-Ho Lin, Benita Jin, Laura A. DeNardo, Douglas L. Black, Julian P. Whitelegge, James A. Wohlschlegel, Karen Reue, Kalyanam Shivkumar, Feng-Jung Chen, Stephen G. Young, Peng Li, Peter Tontonoz
Publikováno v:
Nature
Multilocular adipocytes are a hallmark of thermogenic adipose tissue(1,2), but the factors that enforce this cellular phenotype are largely unknown. Here, we show that an adipocyte-selective product of the Clstn3 locus (CLSTN3β) present in only plac
Autor:
Shilpa Hebbar, Ganesh Panzade, Ajay A. Vashisht, James A. Wohlschlegel, Isana Veksler-Lublinsky, Anna Y. Zinovyeva
Publikováno v:
Scientific Reports. 12
microRNAs (miRNAs) are crucial for normal development and physiology. To identify factors that might coordinate with miRNAs to regulate gene expression, we used 2′O-methylated oligonucleotides to precipitate Caenorhabditis elegans let-7, miR-58, an
Autor:
Nehuén Salas, Veronica M. Coceres, Tuanne dos Santos Melo, Antonio Pereira-Neves, Vanina G. Maguire, Tania M. Rodriguez, Bruna Sabatke, Marcel I. Ramirez, Jihui Sha, James A. Wohlschlegel, Natalia de Miguel
Publikováno v:
Cellular and Molecular Life Sciences. 79
Autor:
Yasaman Jami-Alahmadi, Jihui Sha, Colette L. Picard, Ivy Kwok, Javier Gallego-Bartolomé, C. Jake Harris, Shan Hua, Zhenhui Zhong, Suhua Feng, James A. Wohlschlegel, Jason Gardiner, Steven E. Jacobsen, Ming Wang, Xueshi Cao, Yan Xue
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
The Microrchidia (MORC) family of ATPases are required for transposable element (TE) silencing and heterochromatin condensation in plants and animals, and C. elegans MORC-1 has been shown to topologically entrap and condense DNA. In Arabidopsis thali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ac68b218d8c6710da9b15869912ab2
https://www.repository.cam.ac.uk/handle/1810/327927
https://www.repository.cam.ac.uk/handle/1810/327927
Autor:
Tiantian Su, Deshu Lin, James A. Wohlschlegel, Xu Wang, Zhensheng Gao, Qin Wang, Xiaohua Hu, Chentao Lin, Hsiaochi Huang, Yadi Chen, Huibo Ren, Siyuan Liu
Publikováno v:
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Cryptochromes (CRYs) are photoreceptors or components of the molecular clock in various evolutionary lineages, and they are commonly regulated by polyubiquitination and proteolysis. Multiple E3 ubiquitin ligases regulate CRYs in animal models, and pr
Autor:
Linhao Xu, Zhenhui Zhong, Suhua Feng, Steven E. Jacobsen, James A. Wohlschlegel, Israel Ausin, Yaxin Zhang, Zonghua Wang, Shima Rayatpisheh, Yafei Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
In eukaryotes, DNA wraps around histones to form nucleosomes, which are compacted into chromatin. DNA-templated processes, including transcription, require chromatin disassembly and reassembly mediated by histone chaperones. Additionally, distinct hi
Autor:
William D. Barshop, C. Jake Harris, Qikun Liu, Fei Sun, Michael Carey, James A. Wohlschlegel, Calvin Nguyen, Zhenhui Zhong, Lingyu Zhan, Magdalena E. Potok, Sylvain Bischof, Andrew Q. Rashoff, Jeff A. Long, Suhua Feng, Steven E. Jacobsen, Javier Gallego-Bartolomé, Jixian Zhai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Mediator 12 (MED12) and MED13 are components of the Mediator multi-protein complex, that facilitates the initial steps of gene transcription. Here, in an Arabidopsis mutant screen, we identify MED12 and MED13 as positive gene regulators, both of whic
Autor:
Bertrand Llorente, Pierre-Henri L. Gaillard, Pierre-Marie Dehé, Arato Takedachi, Stéphane Coulon, Paul Shanahan, John R. Yates, Sarah Scaglione, James A. Wohlschlegel, Paul Russell
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2013, 20 (5), pp.598-603. ⟨10.1038/nsmb.2550⟩
Nature Structural and Molecular Biology, 2013, 20 (5), pp.598-603. ⟨10.1038/nsmb.2550⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2013, 20 (5), pp.598-603. ⟨10.1038/nsmb.2550⟩
Nature Structural and Molecular Biology, 2013, 20 (5), pp.598-603. ⟨10.1038/nsmb.2550⟩
Structure-specific DNA endonucleases have critical roles during DNA replication, repair and recombination, yet they also harbor the potential for causing genome instability. Controlling these enzymes may be essential to ensure efficient processing of
Publikováno v:
Scientific Reports
Covalent attachment of the small ubiquitin-like modifier (SUMO) to key targets in the proteome critically regulates the evolutionarily conserved processes of cell cycle control, transcription, DNA replication and maintenance of genome stability. The