Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hui K. Gan"'
Autor:
Maximilian J. Mair, Rupert Bartsch, Emilie Le Rhun, Anna S. Berghoff, Priscilla K. Brastianos, Javier Cortes, Hui K. Gan, Nancy U. Lin, Andrew B. Lassman, Patrick Y. Wen, Michael Weller, Martin van den Bent, Matthias Preusser
Publikováno v:
Nature Reviews Clinical Oncology. 20:372-389
Antibody–drug conjugates (ADCs), a class of targeted cancer therapeutics combining monoclonal antibodies with a cytotoxic payload via a chemical linker, have already been approved for the treatment of several cancer types, with extensive clinical d
Autor:
Ganessan Kichenadasse, Kathy Zhang, Zhiyu Tang, Linda Mileshkin, Jason D. Lickliter, Mark Voskoboynik, Hui K Gan, Michael Millward, Maggie Zhang
Publikováno v:
British Journal of Cancer. 126:576-585
Background Pamiparib, a PARP1/2 inhibitor, demonstrated antitumor activity in preclinical models. Methods This Phase 1A/1B dose-escalation/dose-expansion study enrolled adults (≥18 years) with advanced/metastatic cancer. The dose-escalation phase e
Autor:
Wanping Geng, Christian Wichmann, Yit Wooi Goh, Angela Rigopoulos, Diana Cao, Linghui Li, Hui K Gan, Yan Lan, Nhi Huynh, Fiona Scott, Andrew M. Scott, Alexander Franklin McDonald, Anup Zutshi, Zhanqi Liu, Sylvia J. Gong, Nancy Guo, Uwe Ackermann, Ingrid Burvenich, Graeme O'Keefe
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:3075-3088
Τhis study aimed to optimize the 89Zr-radiolabelling of bintrafusp alfa investigational drug product and controls, and perform the in vitro and in vivo characterization of 89Zr-Df-bintrafusp alfa and 89Zr-Df-control radioconjugates. Bintrafusp alfa
Autor:
Jason D. Lickliter, Mark Voskoboynik, Linda Mileshkin, Hui K. Gan, Ganessan Kichenadasse, Kathy Zhang, Maggie Zhang, Zhiyu Tang, Michael Millward
Publikováno v:
British Journal of Cancer. 126:310-310
Autor:
Hui K Gan, Rachael Chang Lee
Publikováno v:
Targeted Oncology. 14:39-41
Publikováno v:
The AAPS Journal. 20
The selection of therapeutic dose for the most effective treatment of tumours is an intricate interplay of factors. Molecular imaging with positron emission tomography (PET) or single-photon emission computed tomography (SPECT) can address questions
Autor:
Christopher D. Riffkin, Henry S. Friedman, Terrance Grant Johns, Alexander Dobrovic, David M. Ashley, Thomas Mikeska, J A Maxwell, Katharine J. Drummond, Hui K Gan, Andrew H. Kaye, M M Lovric, Christine J. Hawkins
Publikováno v:
British Journal of Cancer
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TRAIL/Apo-2L has shown promise as an anti-glioma drug, based on investigations of TRAIL sensitivity in established glioma cell lines, but it is not known how accurately TRAIL signalling pathways of glioma cells in vivo are reproduced in these cell li