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of 5
pro vyhledávání: '"Hew D.T. Torrance"'
Autor:
Hew D.T. Torrance, Russell Hewson, Shih Pin Lin, Christopher J. Kirwan, John R. Prowle, Rupert M Pearse, Parjam Zolfaghari, Karim Brohi, Michael J. O’Dwyer, Ryan W Haines, Anita West
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Acute Kidney Injury (AKI) complicating major trauma is associated with increased mortality and morbidity. Traumatic AKI has specific risk factors and predictable time-course facilitating diagnostic modelling. In a single centre, retrospective observa
Autor:
Hew D.T. Torrance, Helen C. Owen, Michael J. O’Dwyer, Charles J. Hinds, Rupert M Pearse, E. R. Longbottom
Publikováno v:
Intensive Care Medicine Experimental
Introduction\ud \ud The post-operative period is characterised by increased IL-6 production and clinical features of immune suppression. In vitro anti-inflammatory actions of IL-6 are mediated through suppression of interferon gamma (IFNγ) [1]. The
Publikováno v:
Intensive Care Medicine Experimental
We have demonstrated that traumatic injury is associated with an early immunosuppressive response, the extent of which is associated with an increased risk of developing nosocomial infections. In particular, the expression of the immunosuppressive cy
Autor:
Rupert M Pearse, Hew D.T. Torrance, Michael J. O’Dwyer, Charles J. Hinds, Karim Brohi, Eva Wozniak, John R. Prowle, Charles A. Mein
Publikováno v:
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Objective: To explore the hypothesis that blood transfusion contributes to an immunosuppressed phenotype in severely injured patients. Background: Despite trauma patients using disproportionately large quantities of blood and blood products, the immu
Publikováno v:
Critical Care
Identifying a group of patients at high risk of developing infectious complications is the first step in the introduction of effective pre-emptive therapies in specific patient groups. Quantifying cytokine gene expression also furthers our understand