Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Andres J. Klein-Szanto"'
Autor:
Bartosz Mucha, Shuo Qie, Sagar Bajpai, Vincenzo Tarallo, J. Nathaniel Diehl, Frank Tedeschi, Gao Zhou, Zhaofeng Gao, Samuel Flashner, Andres J. Klein-Szanto, Hanina Hibshoosh, Shimonosono Masataka, Olga S. Chajewski, Ireneusz Majsterek, Dariusz Pytel, Maria Hatzoglou, Channing J. Der, Hiroshi Nakagawa, Adam J. Bass, Kwok-Kin Wong, Serge Y. Fuchs, Anil K. Rustgi, Eckhard Jankowsky, J. Alan Diehl
Publikováno v:
Nature Communications. 13
Heterogeneous Nuclear Ribonucleoprotein K (hnRNPK) is a multifunctional RNA binding protein (RBP) localized in the nucleus and the cytoplasm. Abnormal cytoplasmic enrichment observed in solid tumors often correlates with poor clinical outcome. The me
Autor:
Sushil Kumar, Ajeya Nandi, Snahlata Singh, Rohan Regulapati, Ning Li, John W. Tobias, Christian W. Siebel, Mario Andres Blanco, Andres J. Klein-Szanto, Christopher Lengner, Alana L. Welm, Yibin Kang, Rumela Chakrabarti
Publikováno v:
Nature Communications. 13
Autor:
Flavio Rizzolio, Isabella Caligiuri, Chiara Lucchetti, Matteo Castronovo, Luigi Bagella, Irene Marchesi, Andres J. Klein-Szanto, Antonio Giordano, M Caputo
Publikováno v:
Cell Death & Differentiation. 19:1152-1161
Inactivation of the retinoblastoma protein (pRb) by phosphorylation triggers uncontrolled cell proliferation. Accordingly, activation of cyclin-dependent kinase (CDK)/cyclin complexes or downregulation of CDK inhibitors appears as a common event in h
Autor:
Andres J. Klein-Szanto, Catherine Healy, Sarah A. Tursi, Christine McCauley, R. Paul Wilson, Steven G. Biesecker, Mark Goulian, Çagla Tükel, Gertrude O. Oppong, Glenn J. Rapsinski
Publikováno v:
NPJ Biofilms and Microbiomes
A disruption of epithelial barrier function can lead to intestinal inflammation. Toll-like receptor (TLR) 2 activation by microbial products promotes intestinal epithelial integrity and overall gut health. Several bacterial species, including enteric
Autor:
Andres J. Klein-Szanto, Elizabeth P. Henske, Tiffiney R. Hartman, Emmanuelle Nicolas, Tahseen Al-Saleem, T P Cash, M. C. Simon
Publikováno v:
Oncogene. 28:1594-1604
Birt-Hogg-Dubé (BHD) syndrome is a tumor-suppressor gene disorder characterized by skin tumors, cystic lung disease and renal cell carcinoma. Very little is known about the molecular pathogenesis of BHD. Clinical similarities between BHD and tuberou
Autor:
Kiranmai Gumireddy, George Coukos, le Sage C, Reuven Agami, Dionyssios Katsaros, Mariette Schrier, David A. Egan, Phyllis A. Gimotty, Andres J. Klein-Szanto, Nair S, Remco Nagel, Guanghua Huang, Lin Zhang, Puré E, Qihong Huang, Anping Li
Publikováno v:
Nature Cell Biology. 10:202-210
MicroRNAs (miRNAs) are single-stranded, noncoding RNAs that are important in many biological processes1,2. Although the oncogenic and tumour-suppressive functions of several miRNAs have been characterized, the role of miRNAs in mediating tumour metas
Autor:
Anil K. Rustgi, Sabrina Kim, Munenori Takaoka, Kenji Oyama, Wafik S. El-Deiry, Meenhard Herlyn, Claudia D. Andl, Andres J. Klein-Szanto, Hiroshi Nakagawa, J A Diehl, Takaomi Okawa
Publikováno v:
Oncogene. 26:2353-2364
Epidermal growth factor receptor (EGFR) overexpression and activation is critical in the initiation and progression of cancers, especially those of epithelial origin. EGFR activation is associated with the induction of divergent signal transduction p
Autor:
Andres J. Klein-Szanto, Colin D. Funk, Garret A. FitzGerald, Xin-Sheng Chen, Ying Yu, Dairong Wang, Robert L. Campbell, Jinjin Fan
Publikováno v:
Nature Medicine. 12:699-704
Selective inhibitors of cyclooxygenase-2 (COX2) have attracted widespread media attention because of evidence of an elevated risk of cardiovascular complications in placebo-controlled trials, resulting in the market withdrawal of some members of this
Autor:
Lawrence C. Kenyon, Andres J. Klein-Szanto, Alfredo Fusco, Carlo M. Croce, Ivana De Martino, Rosa Visone, Gustavo Baldassarre, Francesca Pentimalli, Andrea Ciarmiello, Monica Fedele, Giuseppe Viglietto, Sabrina Battista, Claudio Arra
Publikováno v:
Oncogene (Basingstoke) 24 (2005): 3427–3435. doi:10.1038/sj.onc.1208501
info:cnr-pdr/source/autori:Fedele M; Pentimalli F; Baldassarre G; Battista S; Klein-Szanto AJ; Kenyon L; Visone R; De Martino I; Ciarmiello A; Arra C; Viglietto G; Croce CM; Fusco A./titolo:Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone%2Fprolactin cell pituitary adenomas and natural killer cell lymphomas./doi:10.1038%2Fsj.onc.1208501/rivista:Oncogene (Basingstoke)/anno:2005/pagina_da:3427/pagina_a:3435/intervallo_pagine:3427–3435/volume:24
info:cnr-pdr/source/autori:Fedele M; Pentimalli F; Baldassarre G; Battista S; Klein-Szanto AJ; Kenyon L; Visone R; De Martino I; Ciarmiello A; Arra C; Viglietto G; Croce CM; Fusco A./titolo:Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone%2Fprolactin cell pituitary adenomas and natural killer cell lymphomas./doi:10.1038%2Fsj.onc.1208501/rivista:Oncogene (Basingstoke)/anno:2005/pagina_da:3427/pagina_a:3435/intervallo_pagine:3427–3435/volume:24
Overexpression of HMGA1 proteins is a constant feature of human carcinomas. Moreover, rearrangements of this gene have been detected in several human benign tumors of mesenchymal origin. To define the role of these proteins in cell transformation in
Autor:
James Babb, Andres J. Klein-Szanto, John P. Hoffman, Paul F. Engstrom, Hormoz Ehya, Edward R. Sauter, Elin R. Sigurdson, John Malick, Mary B. Daly, Eleftherios P. Diamandis
Publikováno v:
British Journal of Cancer
We previously demonstrated that nipple aspirate fluid (NAF) can be obtained from virtually all non-Asian women between the ages of 30 and 72. The focus of this report is to (1) determine the association of candidate markers of breast cancer risk in N