Zobrazeno 1 - 5
of 5
pro vyhledávání: '"David Lyden"'
Autor:
Mark J. Tomishima, Daniel J. Nolan, Daylon James, Nikica Zaninovic, Marco Seandel, Shahin Rafii, Sina Y. Rabbany, Lorenz Studer, Tyler Janovitz, David Lyden, Robert Benezra, Hyung Song Nam, Zev Rosenwaks, Gabsang Lee
Publikováno v:
Nature Biotechnology. 28:161-166
Previous efforts to differentiate human embryonic stem cells (hESCs) into endothelial cells have not achieved sustained expansion and stability of vascular cells. To define vasculogenic developmental pathways and enhance differentiation, we used an e
Publikováno v:
Cancer and Metastasis Reviews. 25:521-529
Metastasis, the spread of invasive carcinoma to sites distant from the primary tumor, is responsible for the majority of cancer-related deaths (Weigelt, B., Peterse, J. L., & van 't Veer, L. J. (2005). Breast cancer metastasis: Markers and models. Na
Autor:
Shahin Rafii, David Lyden
Publikováno v:
Nature Medicine. 9:702-712
Emerging evidence suggests that bone marrow‐derived endothelial, hematopoietic stem and progenitor cells contribute to tissue vascularization during both embryonic and postnatal physiological processes. Recent preclinical and pioneering clinical st
Publikováno v:
Nature Reviews Cancer. 2:826-835
Summary Tumours recruit neighbouring blood vessels and vascular endothelial cells to support their own blood supply. Recent evidence has indicated, however, that tumours are also capable of mobilizing bone-marrow-derived endothelial precursor cells,
Autor:
Koichi Hattori, Larry Witte, Linda J. Butros, Carla Costa, Pamela Blaikie, Katherine A. Hajjar, Yan Wu, Robert Benezra, Neil R. Hackett, Shahin Rafii, Willy Marks, Malcolm A.S. Moore, Amy Chadburn, David Lyden, Beate Heissig, Zhenping Zhu, Daniel J. Hicklin, Katia Manova, Ronald G. Crystal, Sergio Dias
Publikováno v:
Nature Medicine. 7:1194-1201
The role of bone marrow (BM)-derived precursor cells in tumor angiogenesis is not known. We demonstrate here that tumor angiogenesis is associated with recruitment of hematopoietic and circulating endothelial precursor cells (CEPs). We used the angio