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Publikováno v:
Journal of Molecular Neuroscience. 72:565-573
As one of the main types of secondary craniocerebral injury, the onset, progression, and prognosis of chronic subdural hematoma (CSDH) are closely related to the local inflammation of intracranial hematoma. Atorvastatin is reported to be effective in
Autor:
Philipp Gabriel, Aida Salameh, Beate Rassler, Christian Bölter, Peter Appelt, Nicole Fiedler, Katrin Schierle
Publikováno v:
Pflugers Archiv
Acute normobaric hypoxia may induce pulmonary injury with edema (PE) and inflammation. Hypoxia is accompanied by sympathetic activation. As both acute hypoxia and high plasma catecholamine levels may elicit PE, we had originally expected that adrener
Autor:
Akio Ido, Makoto Matsukubo, Shun Onishi, Mayu Matsui, Satoshi Ieiri, Mitsuru Muto, Toshio Harumatsu, Kotaro Kumagai, Tatsuru Kaji, Waka Yamada, Masakazu Murakami, Keisuke Yano, Koji Yamada, Koshiro Sugita, Ayaka Nagano
Publikováno v:
Pediatric Surgery International
Purpose Total parental nutrition (TPN) causes gastrointestinal mucosal atrophy. The present study investigated the effects of hepatocyte growth factor (HGF) on the intestinal mucosal atrophy induced by TPN. Methods Rats underwent jugular vein cathete
Publikováno v:
Experimental Brain Research. 239:2435-2444
Hypothyroidism causes somatic, psychosocial and affective psychosis, including depression-like behaviors. In this study, (hypothyroidism group; HP group) adult male Sprague Dawley (SD) rats were induced to hypothyroidism after 5 weeks of exposure to
Publikováno v:
Histochemistry and Cell Biology. 155:719-726
We previously reported the immunoreactivity for the vesicular glutamate transporter 2 (VGLUT2) in afferent nerve terminals attached to chemoreceptor type I cells of the carotid body (CB), suggesting that glutamate is released from afferent terminals
Autor:
Sobia Ahsan Halim, Rukhsana Ghaffar, Ahmed Al-Harrasi, Nasiara Karim, Waqar Ahmad, Ajmal Khan, Imran Khan, Nouman Altaf, Abeer Abdelhalim
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 394:929-940
Cisplatin-induced peripheral neuropathic pain is a common adverse effect of chemotherapy. The present study evaluated the effects of 2'-chloro-6-methylflavone (2'-Cl-6MF) at recombinant α1β2γ2L, α2β1-3γ2L, and α3β1-3γ2L GABA-A receptor subty
Publikováno v:
Neuropsychopharmacology
Cocaine abuse continues to be a serious health problem worldwide. Despite intense research, there is still no FDA-approved medication to treat cocaine use disorder (CUD). In this report, we explored the potential utility of beta-caryophyllene (BCP),
Autor:
Robson A.S. Santos, Geovanni Dantas Cassali, Fernando M. Reis, Maíra Casalechi, Virginia M. Pereira, Adelina M. Reis, Sérgio Henrique Sousa Santos
Publikováno v:
Journal of Molecular Histology. 51:639-647
We have previously demonstrated the presence of Angiotensin (Ang)-(1-7) in rat ovary homogenates and its stimulatory effect on estradiol and progesterone production. The present study was undertaken to identify the cellular localization of Ang-(1-7)
Autor:
Muhammed Yayla, Ilknur Calik, Elif Cadirci, Abdulmecit Albayrak, Muhammet Calik, Busra Sirin, Irfan Cinar, Zekai Halici
Publikováno v:
Inflammopharmacology. 28:893-902
This study aimed to demonstrate the role of serotonin 7 receptor (5-HT7) and the effects of 5-HT7 agonists and antagonists in an indomethacin-induced gastric ulcer. Male albino Wistar rats (n = 60) were used in the experiments. LP44 (5-HT7 agonist) a
Autor:
Raphael Mechoulam, Stephen A Collins, Cheryl L. Limebeer, Linda A. Parker, Megan T. Sullivan, Hannah Goodman, Erin M. Rock
Publikováno v:
Psychopharmacology. 237:2621-2631
When acutely administered intraperitoneally, the non-psychoactive cannabinoid cannabidiol (CBD), its acidic precursor cannabidiolic acid (CBDA) and a stable methyl ester of CBDA (HU-580) reduce lithium chloride (LiCl)–induced conditioned gaping in