Zobrazeno 71 - 80
of 17 231
pro vyhledávání: ''
Autor:
S M Ashiqul Islam, Irina I. Abnizova, James McKay, Yudou He, Estelle Chanudet, Behnoush Abedi-Ardekani, Dariush Nasrollahzadeh, Michael Eden, Alisa M. Goldstein, Jon W. Teague, Blandina T. Mmbaga, Nan Hu, Karl Smith-Byrne, Sandra Perdomo, Jingwei Wang, Christine Carreira, Jean-Yves Scoazec, Rebecca C. Fitzgerald, Luis Felipe Ribeiro, Michael R. Stratton, Samad Gharavi, Sergey Senkin, Erik N Bergstrom, Hiva Saffar, Sarah Moody, Sheila Coelho Soares-Lima, Pauline E Bucciarelli, Stefano Serra, Ghislaine Scelo, Charles Dzamalala, Valerie McCormack, Reza Malekzadeh, Hossein Poustchi, Valerie Gaborieau, Lia S Campos, Joshua R. Atkins, Paul Brennan, Emily Thomas, David T. Jones, Paul Richman, Farid Azmoudeh-Ardalan, Masoud Sotoudeh, Ahmadreza Niavarani, Tatsuhiro Shibata, Calli Latimer, Stephen Fitzgerald, Ludmil B Alexandrov, Ricardo Cortez Cardoso Penha, Abdolreza Fazel, Laura Humphreys, Azhar Khandekar, Arash Nikmanesh, Diana Menya
Publikováno v:
Nature Genetics. 53:1553-1563
Esophageal squamous cell carcinoma (ESCC) shows remarkable variation in incidence that is not fully explained by known lifestyle and environmental risk factors. It has been speculated that an unknown exogenous exposure(s) could be responsible. Here w
Autor:
Fang Fang Zhang, Mengyuan Ruan, Diane M. Harris, Donatus U. Ekwueme, Dariush Mozaffarian, Jaya S. Khushalani, Frederick Cudhea, Zhilei Shan
Publikováno v:
Cancer Causes Control
Purpose: Suboptimal diet is a preventable cause of cancer. We aimed to estimate the economic burden of diet-associated cancer among US adults. Methods: We used a Comparative Risk Assessment model to quantify the number of new cancer cases attributabl
Autor:
Hélène Blons, Pierre Laurent-Puig, Laure Gibault, Françoise Le Pimpec-Barthes, Guillaume Beinse, Jean-Baptiste Oudart, Thomas Denize, Jean-Baptiste Leclere, Simon Garinet, Cécile Badoual, Audrey Didelot, Alexandre Perrier, Antoine Legras
Publikováno v:
Br J Cancer
BACKGROUND: Patients with non-small cell lung cancer (NSCLC) receiving curative surgery have a risk of relapse, and adjuvant treatments only translate into a 5% increase in 5-year survival. We assessed the clinical significance of epithelial–mesenc
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Cyclase-associated protein 1 (CAP1) is a ubiquitous protein which regulates actin dynamics. Previous studies have shown that S308 and S310 are the two major phosphorylated sites in human CAP1. In the present study, we aimed to investigate the
Autor:
Anna E. Prizment, Sithara Vivek, Heather H. Nelson, Eileen M. Crimmins, Bharat Thyagarajan, Jessica D. Faul
Publikováno v:
Cancer Causes Control
PURPOSE: The higher prevalence of cognitive impairment/ dementia among cancer survivors is likely multifactorial. Since both exposures to cytomegalovirus (CMV) and inflammation are common among elderly cancer survivors, we evaluated their contributio
Autor:
Xiaoqin Jia, Jieping Chen, Mei Kuang, Yu Hou, Chengfang Zhou, Weiru Wu, Zhe Chen, Zhilong Liu, Yuanyuan Liu, Le Ma, Zhigang Li
Publikováno v:
Leukemia. 36:834-846
FZR1 has been implicated as a master regulator of the cell cycle and quiescence, but its roles and molecular mechanisms in the pathogenesis of severe aplastic anemia (SAA) are unclear. Here, we report that FZR1 is downregulated in SAA HSCs compared w
Publikováno v:
Molecular Neurobiology
Mesenchymal stem cell–derived extracellular vesicles (MSC-EV) can transport microRNAs (miRNAs) into colorectal cancer (CRC) cells, thus to inhibit the malignant phenotype of cancer cells. Whether MSC-EV could deliver miR-34a-5p to suppress CRC deve
Autor:
Nicolas Freynet, Hervé Dombret, Daniel Lusina, Emmanuel Benayoun, Xavier Thomas, Estelle Guérin, Raphael Itzykson, Pascal Turlure, Claude Preudhomme, Laurène Fenwarth, Christine Terré, Aline Renneville, Elise Fournier, Thomas Boyer, Bouchra Badaoui, Isabel Garcia, Cécile Pautas, Thomas Cluzeau, Claude Gardin, Orianne Wagner-Ballon, Matthieu Duchmann, Juliette Lambert, Pierre Fenaux, Meyling Cheok, Bruno Quesnel
Publikováno v:
Leukemia. 36:656-663
The independent prognostic impact of specific dysplastic features in acute myeloid leukemia (AML) remains controversial and may vary between genomic subtypes. We apply a machine learning framework to dissect the relative contribution of centrally rev
Publikováno v:
Molecular Biology Reports. 48:7147-7152
The promoter region is a key element of gene expression regulation. In mammals, most of the genes present, at the level of their promoter, a large number of islands CpG. Age also is seen as another factor for developing breast cell cancer reaching th
Autor:
Salvatore D'Alessandro, Giuseppe Ferrera, Vincenzo Serretta, G. Mortellaro, Francesco Cuccia, Gianfranco Savoca, G. Trapani, Antonio Lo Casto
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:89-95
As the use of hypofractionation has spread in the setting of curative prostate radiotherapy, few data are available in the post-operative scenario. This study reports a mono-institutional experience of moderate post-operative hypofractionated radioth