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Autor:
Assaf, Berger, Kenneth, Bernstein, Juan Diego, Alzate, Reed, Mullen, Joshua S, Silverman, Erik P, Sulman, Bernadine R, Donahue, Anna C, Pavlick, Jason, Gurewitz, Monica, Mureb, Janice, Mehnert, Kathleen, Madden, Amy, Palermo, Jeffrey S, Weber, John G, Golfinos, Douglas, Kondziolka
Publikováno v:
Journal of Neuro-Oncology. 158:471-480
New therapies for melanoma have been associated with increasing survival expectations, as opposed to the dismal outcomes of only a decade ago. Using a prospective registry, we aimed to define current survival goals for melanoma patients with brain me
Autor:
Laura E. Fischer, Sebastian Stintzing, Ludwig Fischer von Weikersthal, Dominik P. Modest, Thomas Decker, Alexander Kiani, Florian Kaiser, Salah-Eddin Al-Batran, Tobias Heintges, Christian Lerchenmüller, Christoph Kahl, Gernot Seipelt, Frank Kullmann, Martina Stauch, Werner Scheithauer, Clemens Giessen-Jung, Jens Uhlig, Bettina Peuser, Claudio Denzlinger, Arndt Stahler, Lena Weiss, Kathrin Heinrich, Swantje Held, Andreas Jung, Thomas Kirchner, Volker Heinemann
Publikováno v:
British Journal of Cancer. 127:836-843
Summary Background The evidence on the efficacy of anticancer therapy is limited in older patients with metastatic colorectal cancer (mCRC). This retrospective analysis of phase III FIRE-3 trial assesses the efficacy of FOLFIRI plus either cetuximab
Autor:
Christelle Nilles, Daniel Delgadillo, Marie Sarazin, Lucia Nichelli, Karima Mokhtari, Bertrand Mathon, Sylvain Choquet, Loïc Feuvret, Agusti Alentorn, Monica Ribeiro, Khê Hoang-Xuan, Caroline Houillier
Publikováno v:
Journal of Neuro-Oncology. 158:99-109
The corpus callosum (CC) is frequently involved in primary central nervous system lymphomas (PCNSLs). In this cohort study, we described the neurocognition of patients with PCNSL-CC and its posttherapeutic evolution.Immunocompetent patients with PCNS
Autor:
Johannes Kerschbaumer, Aleksandrs Krigers, Matthias Demetz, Daniel Pinggera, Julia Klingenschmid, Nadine Pichler, Claudius Thomé, Christian F. Freyschlag
Publikováno v:
Journal of Neuro-Oncology. 158:51-57
Purpose The Clinical Frailty Scale (CFS) evaluates patients’ level of frailty on a scale from 1 to 9 and is commonly used in geriatric medicine, intensive care and orthopedics. The aim of our study was to reveal whether the CFS allows a reliable pr
Autor:
Krischan Braitsch, Alix Schwarz, Katrin Koch, Mara Hubbuch, Helge Menzel, Ulrich Keller, Katharina S. Götze, Florian Bassermann, Peter Herhaus, Mareike Verbeek
Publikováno v:
Annals of Hematology. 101:1311-1319
Reduced intensity conditioning (RIC) and reduced toxicity conditioning (RTC) regimens enable allogeneic hematopoietic stem cell transplantation (alloSCT) to more patients due to reduction in transplant-related mortality (TRM). The conditioning regime
Autor:
Daniel J. George, Neeraj Agarwal, Oliver Sartor, Cora N. Sternberg, Bertrand Tombal, Fred Saad, Kurt Miller, Niculae Constantinovici, Helen Guo, John Reeves, XiaoLong Jiao, Per Sandström, Frank Verholen, Celestia S. Higano, Neal Shore
Publikováno v:
Prostate Cancer and Prostatic Diseases, Vol. 25, no. 2, p. 306-313 (2022)
Background The real-world EPIX study was conducted to gather information about the characteristics of patients with metastatic castration-resistant prostate cancer (mCRPC) who survived ≥2 years after treatment with the alpha-emitter radium-223. Met
Publikováno v:
BMC Cancer. 22
Background Cancer is a major public health problem with pharmacotherapy being the cornerstone of its management. Cancer patients receive multiple drugs concurrently risking Drug-Drug Interactions (DDIs). DDIs, though avoidable, can significantly cont
Autor:
Sweety Gupta, Sumit Singh, Atokali Chophy, Sharanya Nair, Rachit Ahuja, K. Kusum, Deepa Joseph, Rajnish Arora, Amit Gupta, Manoj Gupta
Publikováno v:
Journal of the Egyptian National Cancer Institute. 34
Introduction Brain metastases (BM) are associated with dismal prognosis as they cause significant morbidity and affect the quality of life of patients. Management of BM depends on the following factors: age, patient performance, size and the number o
Autor:
Zoéwendtalé Cyrille Compaoré, Elisabeth Monnet, Aurélie Gérazime, Florence Molinié, Anne-Valérie Guizard, Patricia Delafosse, Tienhan Sandrine Dabakuyo-Yonli, Gaëlle Coureau, Karima Hammas, Sandrine Plouvier, Simona Bara, Gautier Défossez, Bénédicte Lapôtre-Ledoux, Laetitia Daubisse-Marliac, Tania d’Almeida, Guy Launoy, Laura Mansi, Brigitte Trétarre, Anne-Sophie Woronoff
Publikováno v:
Cancer Causes & Control. 33:403-415
In an attempt to understand why cervical cancer (CC) survival is decreasing with diagnosis period among older women in France, this study aimed to estimate the effects of main prognostic factors on net survival in CC according to age.French cancer re
Autor:
Zahra Madjd, Mahdieh Razmi, Sima Saki, Elham Kalantari, Leili Saeednejad Zanjani, Monireh Mohsenzadegan, Fahimeh Fattahi, Maryam Abolhasani
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:609-631
Melanoma-associated antigen A2 (MAGE-A2) is a member of the cancer-testis antigen family differentially overexpressed in a variety of malignancies and is associated with tumor development. However, clinical significance and prognostic value of MAGE-A