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Publikováno v:
Virchows Archiv. 479:947-959
Lymph node metastases are strongly associated with unfavorable prognosis in papillary thyroid carcinoma (PTC) patients. However, there are few sensitive or specific indicators that can diagnose or predict lymph node metastases in PTC. The objective o
Autor:
Stephane Ferretti, Sébastien Jeay, Ensar Halilovic, Claire Fabre, Laurence Van Bree, Christophe Meille, Jens Wuerthner, Florence Hourcade-Potelleret, Sebastian Bauer, Reinhard Dummer, Philippe A. Cassier, Astrid Jullion, George D. Demetri, Nelson Guerreiro, Daniel Shao-Weng Tan
Publikováno v:
British Journal of Cancer
Background CGM097 inhibits the p53-HDM2 interaction leading to downstream p53 activation. Preclinical in vivo studies support clinical exploration while providing preliminary evidence for dosing regimens. This first-in-human phase I study aimed at as
Publikováno v:
Br J Cancer
Background Microwave ablation (MWA) is an effective minimally invasive technique for lung tumours. We aim to evaluate its role for pulmonary oligorecurrence after radical surgery of non-small-cell lung cancer (NSCLC). Methods From June 2012 to Jan 20
Autor:
Joanna Streb, Katarzyna Ewa Tyrak, Krzysztof Okoń, Joanna Szpor, Diana Hodorowicz-Zaniewska, Anna Glajcar, Agnieszka Łazarczyk
Publikováno v:
Virchows Archiv
Luminal A breast cancers are generally associated with low metastatic potential and good prognosis. However, there is a proportion of patients, who present with metastases in lymph nodes. The aim of our study was to determine the association between
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:533-542
Genetic variation in the activation of the prodrug cyclophosphamide (CP) by cytochrome P450 (CYP) enzymes has been shown to influence outcomes. However, CYP are also subject to phenoconversion due to either the effects of comedications or cancer asso
Autor:
David Sefrioui, Ludivine Beaussire, André Gillibert, France Blanchard, Emmanuel Toure, Céline Bazille, Anne Perdrix, Frédéric Ziegler, Alice Gangloff, Mélanie Hassine, Caroline Elie, Anne-Laure Bignon, Aurélie Parzy, Philippe Gomez, Caroline Thill, Florian Clatot, Jean-Christophe Sabourin, Thierry Frebourg, Jacques Benichou, Karine Bouhier-Leporrier, Marie-Pierre Gallais, Nasrin Sarafan-Vasseur, Pierre Michel, Frédéric Di Fiore
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
British Journal of Cancer, Cancer Research UK, 2021, ⟨10.1038/s41416-021-01431-9⟩
Br J Cancer
BACKGROUND: We previously reported that CEA kinetics are a marker of progressive disease (PD) in metastatic colorectal cancer (mCRC). This study was specifically designed to confirm CEA kinetics for predicting PD and to evaluate CA19-9, cell-free DNA
Autor:
Andrzej Skalski, Robert Balawender, Wojciech Kostarczyk, Józefa Job, Maria Pawłowicz, Krzysztof Janc, Maciej Stanuch, Ryszard Wierzbicki
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background The purpose of this study was to investigate the potential of a combination of 3D mixed-reality visualization of medical images using CarnaLife Holo (MedApp, Poland) system as a supporting tool for innovative, minimally invasive surgery/ir
Autor:
Robert H. Reid, Mina Swiha, Daniele Wiseman, Alireza Khatami, Amol Mujoomdar, Golmehr Sistani, Rami M Abazid, Jonathan Romsa, Duncan E. K. Sutherland, David Laidley
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose 177Lu-Dotatate is an emerging treatment modality for patients with unresectable or metastatic well-differentiated NETs. This study examines survival predictors in patients who received 177Lu-Dotatate. Methods A retrospective single-center rev
Autor:
I Lorenzo, Paula Jiménez-Fonseca, M I Del Olmo-García, Ana Custodio, J Á Díaz, Carles Villabona, N Canal, G. de la Cruz, M J Gomez, Alberto Carmona-Bayonas
Publikováno v:
CLINICAL & TRANSLATIONAL ONCOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Clinical & Translational Oncology
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Clinical & Translational Oncology
Purpose To report healthcare resource use and associated costs in controlled versus uncontrolled carcinoid syndrome (CS) in patients with neuroendocrine tumours. Methods A cross-sectional, non-interventional multicentre study was conducted with retro
Autor:
Ehsan Sohrabi, Mansoor Khaledi, Hamed Afkhami, Javad Fathi, Masoumeh Moslemi, Ali Zekri, Ehsan Rezaie, Nahid Nafissi
Publikováno v:
Genes & Genomics. 43:1065-1077
Background: Breast cancer (BC) is a common malignancy with a high mortality rate. Malignant cell transformation is associated with metabolic changes. One group pf proteins that are affected are the monocarboxylate transporters (MCTs-SLC16A). The MCTs