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Publikováno v:
Breast Cancer Research and Treatment. 194:507-516
To compare the outcome of allogeneic stem cell transplantation for myeloid malignancies in breast cancer survivors to a contemporaneous control group.Medical records of all patients with a history of breast cancer who received allogeneic stem cell tr
Autor:
Stephanie Burnett, Amit Bahl, Bruno Morgan, Lucy Tregellas, Lisa Pickering, Alastair Thomson, Emma Hall, Tony Elliott, Rachel Slade, Balaji Venugopal, Steve Nicholson, Naveen S. Vasudev, Holly Tovey, Clare Cruickshank, Peter Kirkbride, Alison Hassall, Anita Mitra
Publikováno v:
British Journal of Cancer
Background We investigated the first-line activity of vinflunine in patients with penis cancer. Cisplatin-based combinations are commonly used, but survival is not prolonged; many patients are unfit for such treatment or experience toxicity that outw
Autor:
Amy E. DeZern, Bhagirathbhai Dholaria, Richard J. Jones, Vikas Gupta, Siddharth Kunte, Asad Bashey, Aaron T. Gerds, Anurag K. Singh, Michael R. Grunwald, Roni Tamari, Michael Ozga, Hany Elmariah, Auro Viswabandya, Lisa Rybicki, Alla Keyzner, Madiha Iqbal, Sameem Abedin, Tania Jain
Publikováno v:
Leukemia
We report the results from a multicenter retrospective study of 69 adult patients who underwent haploidentical blood or marrow transplantation (haplo-BMT) with post-transplantation cyclophosphamide (PTCy) for chronic phase myelofibrosis. The median a
Autor:
Nicolas Freynet, Hervé Dombret, Daniel Lusina, Emmanuel Benayoun, Xavier Thomas, Estelle Guérin, Raphael Itzykson, Pascal Turlure, Claude Preudhomme, Laurène Fenwarth, Christine Terré, Aline Renneville, Elise Fournier, Thomas Boyer, Bouchra Badaoui, Isabel Garcia, Cécile Pautas, Thomas Cluzeau, Claude Gardin, Orianne Wagner-Ballon, Matthieu Duchmann, Juliette Lambert, Pierre Fenaux, Meyling Cheok, Bruno Quesnel
Publikováno v:
Leukemia. 36:656-663
The independent prognostic impact of specific dysplastic features in acute myeloid leukemia (AML) remains controversial and may vary between genomic subtypes. We apply a machine learning framework to dissect the relative contribution of centrally rev
Autor:
Davide Franceschini, Stefano Tomatis, Tiziana Comito, Giacomo Reggiori, Andrea Lania, Ciro Franzese, Ausilia Teriaca, Marta Scorsetti, Maria Massaro, Sara Stefanini, Elena Clerici, Pierina Navarria
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:3619-3625
The purpose of this study was to assess prospectively the efficacy and safety of stereotactic body radiation therapy (SBRT) for adrenal gland metastasis, with a focus on the assessment of the irradiated subjects’ endocrinological function. A total
Autor:
Masashi Mizumoto, Masahide Matsuda, Toshiyuki Okumura, Haruko Numajiri, Eiichi Ishikawa, Yoshiko Oshiro, Hidehiro Kohzuki, Hideyuki Sakurai, Keiichi Tanaka, Akira Matsumura, Hsiang-Kuang Tony Liang
Publikováno v:
Journal of Cancer Research and Clinical Oncology
BackgroundGlioblastoma peritumoral edema (PE) extent is associated with survival and progression pattern after tumor resection and radiotherapy (RT). To increase tumor control, proton beam was adopted to give high-dose boost (> 90 Gy). However, the c
Autor:
Irene Zarra, Angel Carracedo, Rafael López-López, Santiago Aguín, Raquel Cruz, José María Giráldez, Goretti Duran, María Jesús Lamas, Francisco Barros, Beatriz Bernardez
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:813-823
Genetic variants in genes involved in the distribution, metabolism, accumulation or repair of lesions are likely to influence the response of drugs used in the treatment of Head and Neck Cancer (HNC). We examine the effect of 36 SNPs on clinical outc
Autor:
Agnieszka Paradowska-Gorycka, Ewa Walczuk, Katarzyna Romanowska-Próchnicka, Malgorzata Jaronczyk, L N Sivitskaya, Tomasz Wysocki, Jakub Lach, Anna Wajda, Barbara Stypinska, Danat Yermakovich
Publikováno v:
The Pharmacogenomics Journal
Methotrexate (MTX) is the first-line therapy for rheumatoid arthritis. Nevertheless, MTX resistance is quite a common issue in clinical practice. There are some premises that aryl hydrocarbon receptor (AhR) gene battery may take part in MTX metabolis
Autor:
Alberto Zaniboni, Chiara Cremolini, Gianluca Tomasello, Samanta Cupini, Laura Fanchini, Beatrice Borelli, Sara Lonardi, Gianluca Masi, Daniele Rossini, Angela Buonadonna, Carlotta Antoniotti, Veronica Conca, Gemma Zucchelli, Alfredo Falcone, Federica Marmorino, Margherita Ambrosini, Salvatore Caponnetto, Daniele Santini, Cosimo Rasola, Roberto Moretto
Publikováno v:
Br J Cancer
BACKGROUND: In mCRC, CEA is used to monitor response to systemic therapy together with imaging. After the end of induction, no major improvement in tumour shrinkage is expected, and the availability of a marker able to predict progressive disease (PD
Autor:
Xinchen Wang, Qing Liu, Katja Fall, Helga Zoega, Omid Sadr-Azodi, Oskar Halfdanarson, Lars Engstrand, Nele Brusselaers
Publikováno v:
Br J Cancer
The British journal of cancer
The British journal of cancer
Background Proton pump inhibitors (PPIs) are associated with microbiome changes of the gut, which in turn may affect the progression of colorectal cancer (CRC). This study aims to assess the associations between PPI use and all-cause and CRC-specific