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Autor:
Martha A. Zeiger, Zhiyang Liu, Brittany A. McKelvey, Leslie Cope, Christopher B. Umbricht, Yongchun Wang, Lisa M. Rooper
Publikováno v:
J Cancer Res Clin Oncol
BACKGROUND: While molecular testing is a promising strategy for preoperative assessment of cytologically indeterminate thyroid nodules, thyroid fine needle aspiration biopsy (FNA) presents unique challenges for molecular assays, including contaminati
Publikováno v:
Journal of Neuro-Oncology. 152:405-413
The disadvantages of biopsy for lesions in the basal ganglia and thalamus include a risk of various complications, difficulty in selecting the target tissue in some cases due to indistinct neuroimaging findings and limited availability of sample tiss
Autor:
Francesca Grobelny, Christian Wülfing, Cord Matthies, Arlo Radtke, Jacqueline Bodes, Gazanfer Belge, Klaus-Peter Dieckmann
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Serum levels of microRNA-371a-3p (M371) have been shown to be a highly sensitive and specific biomarker for testicular germ cell tumours (TGCT). Little information exists on the expression of this marker in testicular neoplasms deriving from
Autor:
Tae Hyun Yoo, Gyuri Kim, Seonghun Kim, Shin Wook Kang, Jeongho Joo, Huiyoon Shin, Bo Young Nam, Jung Tak Park, Jimin Park, Pureunchowon Lee, Seung Hyeok Han
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-1 (2021)
Cell Death and Disease, Vol 12, Iss 4, Pp 1-1 (2021)
Kidney tubular cell death induced by transforming growth factor-β1 (TGF-β1) is known to contribute to diabetic nephropathy, a major complication of diabetes. Caspase-3-dependent apoptosis and caspase-1-dependent pyroptosis are also involved in tubu
Autor:
P Palomo, C. Quirós, Segundo Gonzalez, Iván Fernández-Vega, Angel Ramirez Payer, S. Alonso-Álvarez, A P González, R Alonso-Arias, Enrique Colado, J A Villegas, Marco Antonio Moro-García, B López-Pereira, Teresa Bernal, D Corte-Torres, A A Fernández-Velasco
Publikováno v:
Clinical and Translational Oncology. 22:782-785
CD47 over expression has been reported in several tumor subtypes. CD47 interacts with SIRPalpha on macrophages inhibiting phagocytic signal, providing a survival advantage to tumor. CD47, therefore, represents a valuable target for immunotherapy and
Autor:
Luca Malcovati, Erica Travaglino, Anna Gallì, Kavita Raj, Virginia Valeria Ferretti, Elisa Bono, Jie Jiang, Chiara Elena, Emanuela Boveri, Antonio Bianchessi, Gabriele Todisco, Robin M. Ireland, Austin G. Kulasekararaj, Alesia Abigael Khan, Judith C. W. Marsh, Ghulam J. Mufti, Donal P. McLornan, Mario Cazzola, Shreyans Gandhi
Publikováno v:
Leukemia. 33:2495-2505
Diagnostic criteria for hypoplastic myelodysplasic syndrome (h-MDS) have not been clearly established, making the differential diagnosis from other bone marrow failure syndromes (BMF) challenging. In this study, we aimed to delineate clinical, histop
Publikováno v:
Journal of Neuro-Oncology. 140:289-296
Extraventricular neurocytoma (EVN) is an exceedingly rare tumor. In this study, we sought to characterize the imaging and pathological features of this uncommon tumor. Retrospective review of 18 patients (9 male; 9 female) with pathologically confirm
Autor:
Makoto Ohno, Yuko Matsushita, Yoshitaka Narita, Koichi Ichimura, Yosuke Kitagawa, Yasuji Miyakita, Takahiro Yamauchi, Akihiko Yoshida, Kaishi Satomi, Natsuko Tsushita, Masamichi Takahashi, Erika Kondo
Publikováno v:
Brain Tumor Pathology. 35:148-158
The radiological features of lower-grade gliomas (LGGs) classified according to isocitrate dehydrogenase (IDH) mutations and codeletion of chromosomal arms 1p and 19q (1p/19q codeletion) remain unclear. We aimed to systematically characterize the rad
Autor:
Atsushi Natsume, Akane Yamamichi, Yukinari Kato, Masaki Hirano, Kuniaki Tanahashi, Akira Kato, Kazuya Motomura, Hiromichi Suzuki, Fumiharu Ohka, Kosuke Aoki, Toshihiko Wakabayashi, Lushun Chalise, Sachi Maeda
Publikováno v:
Brain Tumor Pathology. 35:106-113
The IDH-mutant and 1p/19q co-deletion (1p19q codel) provides significant diagnostic and prognostic value in lower-grade gliomas. As ATRX mutation and 1p19q codel are mutually exclusive, ATRX immunohistochemistry (IHC) may substitute for 1p19q codel,
Autor:
Naoko Sato, Ryohei Sasaki, Yusuke Yamamoto, Masaaki Kohta, Kazuhiro Tanaka, Takashi Sasayama, Kohkichi Hosoda, Eiji Kohmura, Junichi Sakata, Katsusuke Kyotani, Masahiro Maeyama, Hiroaki Nagashima, Tomoo Itoh
Publikováno v:
Journal of Neuro-Oncology. 136:317-326
It is sometimes difficult to distinguish gliomas from other tumors on routine imaging. In this study, we assessed whether 3-T magnetic resonance spectroscopy (MRS) with LCModel software might be useful for discriminating glioma from other brain tumor