Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yik Ying Teo"'
Autor:
Esteban J. Parra, E-Shyong Tai, Habiba Alsafar, Enrico Petretto, Jirong Long, Amelia Li Min Tan, Xueling Sim, Yik Ying Teo, Miguel Cruz, Huimei Chen, Qiuju Ding
Publikováno v:
Journal of Human Genetics. 65:411-420
Genome-wide association studies (GWASs) have identified many genetic variations associated with type 2 diabetes mellitus (T2DM) in Asians, but understanding the functional genetic variants that influence traits is often a complex process. In this stu
Autor:
Maude E. Phipps, Boon Peng Hoh, Yan Lu, Thuhairah Hasrah Abdul Rahman, Yushimah Yunus, Rick Twee-Hee Ong, Farhang Aghakhanian, Chee Wei Yew, Xiaoji Wang, Yik Ying Teo, Mohammad Zahirul Hoque, Christopher Lok Yung Voo, Jong Bhak, Dongsheng Lu, Shuhua Xu, Lai-Ping Wong, Lian Deng, Subbiah Vijay Kumar, Siti Shuhada Mokhtar
Publikováno v:
Human Genetics. 137:161-173
Southeast Asia (SEA) is enriched with a complex history of peopling. Malaysia, which is located at the crossroads of SEA, has been recognized as one of the hubs for early human migration. To unravel the genomic complexity of the native inhabitants of
Autor:
Jeeyun Ahn, Ian Yeo, Ranjana Mathur, Chi Pui Pang, Chan Choi Mun, Tien Yin Wong, Chiea Chuen Khor, Qiao Fan, Nagahisa Yoshimura, Yik Ying Teo, Tock Han Lim, Kenji Yamashiro, Li Jia Chen, Augustinus Laude, Ching-Yu Cheng, Kyu Hyung Park, Chui Ming Gemmy Cheung
Publikováno v:
Journal of Human Genetics. 62:1049-1055
Polypoidal choroidal vasculopathy (PCV), a subtype of age-related macular degeneration (AMD) more frequently seen in East Asians, has both common and distinct clinical manifestations with typical neovascular AMD (tAMD). We aim to examine the extent t
Autor:
Anuradhani Kasturiratne, Li Jin, Fumihiko Takeuchi, Dongsheng Lu, Xuanyao Liu, Takayoshi Ohkubo, Dolikun Mamatyusupu, Shuhua Xu, Norihiro Kato, Yik-Ying Teo, Woei-Yuh Saw, Tran Nguyen Bich Chau, Sissades Tongsima, Tomohiro Katsuya, Yasuharu Tabara, Ken Yamamoto, Boon Peng Hoh, H. Janaka de Silva, Ryosuke Kimura, Worachart Lert-itthiporn, Sarah J. Dunstan, Prapat Suriyaphol, Kwanrutai Chin-inmanu, Yeun-Jun Chung, Pongsakorn Wangkumhang, Cameron P. Simmons, Mitsuhiro Yokota, Toru Nabika, Katie Anders, RickTwee-Hee Ong, Chiea Chuen Khor, Philip J. Shaw, Wenjun Yang, Ananda R. Wickremasinghe, Chumpol Ngamphiw, Suthat Fucharoen
Publikováno v:
European Journal of Human Genetics. 25:499-508
The Asian Diversity Project (ADP) assembled 37 cosmopolitan and ethnic minority populations in Asia that have been densely genotyped across over half a million markers to study patterns of genetic diversity and positive natural selection. We performe
Publikováno v:
European Journal of Human Genetics. 24:1651-1657
Pharmacogenomics has been lauded as an important innovation in clinical medicine as a result of advances in genomic science. As one of the cornerstones in precision medicine, the vision to determine the right medication in the right dosage for the ri
Autor:
Jin Zhou, Yik Ying Teo
Publikováno v:
European Journal of Human Genetics. 24:1195-1201
Investigating how an ancestral population diverges to give rise to distinct subpopulations remains a fundamental pursuit in population genetics. There is broad consensus for the ‘Out-of-Africa' hypothesis that states that modern humans arose ∼200
Autor:
Jiemin Liao, E-Shyong Tai, Yik Ying Teo, Chiea Chuen Khor, Peter Little, Jianjun Liu, Kee Seng Chia, Tin Aung, Ching-Yu Cheng, Xu Wang, Xueling Sim, Tien Yin Wong
Publikováno v:
European Journal of Human Genetics. 24:592-599
There has been limited success in identifying causal variants underlying association signals observed in genome-wide association studies (GWAS). The use of 1000 Genomes Project (1KGP) allows the imputation to estimate the genetic information at untyp
Publikováno v:
BMC Genomics
Background Whole-genome sequencing is increasingly used in clinical diagnosis of tuberculosis and study of Mycobacterium tuberculosis complex (MTC). MTC consists of several genetically homogenous mycobacteria species which can cause tuberculosis in h
Autor:
Wenting Xu, Kalisvar Marimuthu, Oon Tek Ng, Wei Xin Khong, Eryu Xia, Brenda Ang, Shiyong Neo, Yik Ying Teo, Eng Lee Tan, David C. Lye, Angela Chow, Rick Twee-Hee Ong, Prabha Krishnan
Publikováno v:
BMC Genomics
New Delhi metallo-β-lactamase (bla NDM), a plasmid-borne carbapenemase gene associated with significant mortality and severely limited treatment options, is of global public health concern as it is found in extremely diverse Gram-negative bacterial
Autor:
Guanghou Shui, Peter Little, Rick Twee-Hee Ong, Yik Ying Teo, Amaury Cazenave-Gassiot, Bowen Li, Husna Begum, Richie Soong, Markus R. Wenk
Publikováno v:
Scientific Reports
Lipid levels are commonly used in clinical settings as disease biomarkers and the advent of mass spectrometry-based (MS) lipidomics heralds the possibility of identifying additional lipids that can inform disease predispositions. However, the degree