Zobrazeno 1 - 10
of 3 823
pro vyhledávání: ''
Publikováno v:
Mol Neurobiol
Sex differences in opioid analgesia occur in rodents and humans, and could be due to differences in drug and metabolite levels. Thus, we investigated the sex and cycle differences in analgesia (nociception) from oxycodone in rats and related these to
Autor:
Gagana Karkada, G. Arun Maiya, Praveen R. Arany, Mohandas Kg Rao, Shobha U. Kamath, Shalini Adiga
Publikováno v:
Cell Biochemistry and Biophysics. 80:151-160
BackgroundProlonged and overlapping phases of wound healing in diabetes are mainly due to the redox imbalance resulting in the chronicity of the wound. Photobiomodulation therapy works on the principle of absorption of photon energy and its transduct
Publikováno v:
Annals of Hematology
Immune thrombocytopenia (ITP) is a disease of heterogenous origin characterized by low platelet counts and an increased bleeding tendency. Three disease phases have been described: newly diagnosed (≤ 3 months after diagnosis), persistent (> 3–12
Autor:
Alessandro Iandolo, Giovanni Alma, Giosuè Santoro, Franco Guarnaccia, Mariarosaria De Luca, Emanuele Romeo, Ferdinando Ferrara, Maurizio Olivares, Ugo Oliviero, Giovanni Battista Zito, Biagio Fimiani, Giorgio Bosso, Antonio Valvano, Sabato Murolo, Vincenzo Carbone
Publikováno v:
Internal and Emergency Medicine. 17:387-395
The association between LDL-c levels and cardiovascular outcomes suggests tailoring lipid-lowering therapies according to total cardiovascular risk. We aimed to evaluate the adherence to guidelines-oriented dyslipidaemia’s treatment in an outpatien
Autor:
Parminder Singh, Irbaz Bin Riaz, Cassandra N. Moore, Heidi E. Kosiorek, Renee K. Sharpsten, Andrea McNatty, Glenn A. Stewart, Steven R. Hwang, Alan H. Bryce, Thai H. Ho, Jan B. Egan, Miguel Gonzalez Velez, Brian A. Costello
Publikováno v:
Prostate Cancer and Prostatic Diseases. 25:479-483
Background Altered tumor suppressor genes (TSG-alt) in prostate cancer are associated with worse outcomes. The prognostic value of TSG-alt in metastatic, hormone-sensitive prostate cancer (M1-HSPC) is unknown. We evaluated the effects of TSG-alt on o
Autor:
Anna Boguszewska-Czubara, Maria Zykubek, Łukasz Kurach, Agnieszka Michalak, Olga Wronikowska, Barbara Budzyńska
Publikováno v:
Psychopharmacology
Rationale Mephedrone is a frequently overused drug of abuse that belongs to the group of novel psychoactive substances. Although its mechanism of action, as well as toxic and psychoactive effects, has been widely studied, the role of different factor
Autor:
Emmanuel Ampofo, Maximilian M Menger, Matthias W. Laschke, Michael D. Menger, Leticia Prates Roma, Lisa Nalbach
Publikováno v:
Acta Diabetologica
Aims The exposure of isolated pancreatic islets to pro-angiogenic factors prior to their transplantation represents a promising strategy to accelerate the revascularization of the grafts. It has been shown that erythropoietin (EPO), a glycoprotein re
Autor:
Władysława A. Daniel, Paulina Surówka, Patrycja Kleczkowska, Magdalena Zadrożny-Bujalska, Joanna Jastrzębska, Renata Pieniążek, Agata Suder, Renata Pukło, Małgorzata Filip, Małgorzata Frankowska
Publikováno v:
Pharmacological Reports
Background Opioid use disorders are serious contributors to the harms associated with the drug use. Unfortunately, therapeutic interventions for opioid addicts after detoxification have been limited and not sufficiently effective. Recently, several s
Autor:
Asmaa M A Bayoumi, Sayed Shehata, Marwa M.M. Refaie, Walaa Yehia Abdelzaher, Nashwa Fathy Gamal El-Tahawy
Publikováno v:
Cardiovascular Drugs and Therapy. 36:817-827
The cardiotoxicity of anticancer drugs such as 5-fluorouracil (5FU) is a major complication that challenges their clinical usefulness. Thus there is a critical need to find new protective drugs to defend against these harmful side effects. Up to now,
Publikováno v:
Cardiovascular Toxicology. 21:790-799
Sirtuins are regulators of eNOS and endothelial function; however, no studies have examined the influence of exercise on sirtuin regulation of endothelial function. Effects of the novel sirtuin inhibitor, salermide, on vascular reactivity in rat aort