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Autor:
Kumar, J. Kiran, Aronsson, A. C., Pilko, G., Zupan, M., Kumer, K., Fabjan, T., Osredkar, J., Eriksson, S.
Publikováno v:
Tumour Biology
Thymidine kinase (TK1) is an enzyme involved in DNA synthesis that leaks into the blood as a result of high cell turnover, particularly in the case of cancer. Serum TK1 activity has been used for prognosis and monitoring of leukemia and lymphoma pati
Autor:
Agnieszka Szymczyk, Waldemar Różański, Beata Smolarz, Paweł Jóźwiak, Magdalena Bryś, Ewa Brzeziańska, Hanna Romanowicz-Makowska, Grażyna Chwatko, Anna Krześlak, Ewa Forma
Publikováno v:
Molecular Biology Reports
Topoisomerase IIb binding protein 1 (TopBP1) is involved in cell survival, DNA replication, DNA damage repair and cell cycle checkpoint control. The biological function of TopBP1 and its close relation with BRCA1 prompted us to investigate whether al