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Autor:
Qiufeng Lv, Limei Han, Jiancheng Yang, Jianmin Hu, Shumei Lin, Ying Feng, Gaofeng Wu, Qunhui Yang
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789402410778
Taurine has been reported to have anti-arrhythmia effects, but the anti-atrial fibrillation (AF) effects and its mechanism remain incompletely understood. In the present study, the therapy effects and partly mechanisms were investigated. AF animal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c7925cce8506aee4135e77b3bb41b8
https://doi.org/10.1007/978-94-024-1079-2_65
https://doi.org/10.1007/978-94-024-1079-2_65
Autor:
Ying Feng, Jiancheng Yang, Jianmin Hu, Man Feng, Mei Liu, Qiufeng Lv, Shumei Lin, Qunhui Yang
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789402410778
Objective: To study the preventive actions and mechanism of taurine on the electrical remodeling in atrial fibrillation (AF) rats. Methods: Male Wistar rats were injected with the mixture of acetylcholine (Ach) (66 μg/mL)-CaCl2 (10 mg/mL) (i.v.) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63eeb3bc2515b59c2e2092e122d6468
https://doi.org/10.1007/978-94-024-1079-2_64
https://doi.org/10.1007/978-94-024-1079-2_64
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789401792448
The nicotinic acetylcholine receptors (nAChRs) are ion channels distribute in the central or peripheral nervous system. They are receptors of the neurotransmitter acetylcholine and activation of them by agonists mediates synaptic transmission in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166f7aaaf1ce84a9c8c447f52291fb88
https://doi.org/10.1007/978-94-017-9245-5_21
https://doi.org/10.1007/978-94-017-9245-5_21
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789400745483
Phosphodiesterases (PDEs) are enzymes responsible for degradation of cAMP and cGMP in cells. Thus, PDE inhibitors may have significant clinical benefit in respiratory diseases associated with inflammation. The aim of the present study was to evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad5afc88f5c5a86046e2a0a9dd1de268
https://doi.org/10.1007/978-94-007-4549-0_8
https://doi.org/10.1007/978-94-007-4549-0_8
Publikováno v:
Biomedical Aspects of Histamine ISBN: 9789048193486
Histamine regulates pre- and post-synaptically several brain functions, through the interaction with G protein-coupled receptors. Four such receptors (H1–H4) have been cloned, and three of them (H1, H2, and H3) are widely distributed in the mammali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695454555588bc0f845167ff3c90bb2b
https://doi.org/10.1007/978-90-481-9349-3_15
https://doi.org/10.1007/978-90-481-9349-3_15
Publikováno v:
Cell Signalling in Prokaryotes and Lower Metazoa ISBN: 9789048164837
Nematodes include both major parasites of humans, livestock and plants and free-living species such as Caenorhabditis elegans. The nematode nervous system (especially in C. elegans) is exceptionally well defined in terms of the number, location and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dca51a4091cdd7791b310411bead510b
https://doi.org/10.1007/978-94-017-0998-9_8
https://doi.org/10.1007/978-94-017-0998-9_8
Publikováno v:
Peptides: The Wave of the Future ISBN: 9789401039055
The primary physiological role of acetylcholinesterase (AChE) is to hydrolyze the neurotransmitter acetylcholine at cholinergic synapses. AChE is among the most efficient enzymes, with a turnover number of >104 s-1 [1]. Ligand binding studies and X-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3bbfb18d0db5d992bf0686a17124136
https://doi.org/10.1007/978-94-010-0464-0_263
https://doi.org/10.1007/978-94-010-0464-0_263
Publikováno v:
NBC Risks Current Capabilities and Future Perspectives for Protection ISBN: 9780792358039
Conventional medical treatment against the toxicity of organophosphorus (OP) compound consists of anticholinergic drugs to counteract the accumulation of acetylcholine and oximes to reactivate OP-inhibited acetylcholinesterase (AChE). Although, both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4242676fac5e4951e396397c33d8aab
https://doi.org/10.1007/978-94-011-4641-8_12
https://doi.org/10.1007/978-94-011-4641-8_12
Autor:
Robert F. Furchgott
Publikováno v:
Diabetic Renal-Retinal Syndrome ISBN: 9789401060837
Furchgott’s epochal discovery in 1980 of endothelium-dependent relaxation of arteries by acetylcholine led to identification of a labile material released by endothelial cells first termed endothelium-derived relaxing factor and later shown to be n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6796e017b7a55db9e1218856c40c923
https://doi.org/10.1007/978-94-011-4962-4_15
https://doi.org/10.1007/978-94-011-4962-4_15
Publikováno v:
Modelling of Biomolecular Structures and Mechanisms ISBN: 9789401042222
The principal biological role of acetylcholinesterase (AChE) is termination of impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine (ACh). Based on our recent X-ray crystallographic structure determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8953bea0c5c2ca11ee9abc481487ed23
https://doi.org/10.1007/978-94-011-0497-5_34
https://doi.org/10.1007/978-94-011-0497-5_34