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Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789400745483
Phosphodiesterases (PDEs) are enzymes responsible for degradation of cAMP and cGMP in cells. Thus, PDE inhibitors may have significant clinical benefit in respiratory diseases associated with inflammation. The aim of the present study was to evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad5afc88f5c5a86046e2a0a9dd1de268
https://doi.org/10.1007/978-94-007-4549-0_8
https://doi.org/10.1007/978-94-007-4549-0_8
Publikováno v:
Biomedical Aspects of Histamine ISBN: 9789048193486
Histamine regulates pre- and post-synaptically several brain functions, through the interaction with G protein-coupled receptors. Four such receptors (H1–H4) have been cloned, and three of them (H1, H2, and H3) are widely distributed in the mammali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695454555588bc0f845167ff3c90bb2b
https://doi.org/10.1007/978-90-481-9349-3_15
https://doi.org/10.1007/978-90-481-9349-3_15
Autor:
W. G. Richards, C. R. Ganellin
Publikováno v:
The Jerusalem Symposia on Quantum Chemistry and Biochemistry ISBN: 9789401017602
Many physiologically important amines are conformational flexible molecules. Compounds such as acetylcholine, histamine, adrenaline and serotonin can have their conformational energies displayed on two dimensional maps which show energy contours rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b672092fc0afd94a63ce82a582ed2f1
https://doi.org/10.1007/978-94-010-1758-9_27
https://doi.org/10.1007/978-94-010-1758-9_27