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Autor:
Piotr Gruca, Marta Dziedzicka-Wasylewska, Maciej Kuśmider, Joanna Solich, Paulina Pabian, Mariusz Papp, Agata Faron-Górecka, Dariusz Żurawek, Magdalena Kolasa, Kinga Szafran-Pilch
Publikováno v:
Psychopharmacology
Rationale The involvement of somatostatin (SST) and its receptors in the pathophysiology of depression and stress has been evidenced by numerous studies. Objectives The purpose of the present study was to find whether chronic mild stress (CMS), an an
Publikováno v:
Pflugers Archiv
Specific small interfering RNA (siRNA) constructs were used to test for the functional relation of subunits alpha, beta, and gamma of the epithelial Na(+) channel (ENaC) to the hypertonicity-induced cation channel (HICC) in confluent rat hepatocytes.
Publikováno v:
Pflugers Archiv
Ion transport activity in pancreatic alpha-cells was assessed by studying cell volume regulation in response to anisotonic solutions. Cell volume was measured by a video imaging method, and cells were superfused with either 4-(2-hydroxyethyl)piperazi
Autor:
Alexa H. Veenema, Aarane M. Ratnaseelan, Sara J. Li, Caroline J. Smith, Remco Bredewold, Max L. Poehlmann
Publikováno v:
Brain Structure & Function
Oxytocin (OT) and vasopressin (AVP) regulate various social behaviors via activation of the OT receptor (OTR) and the AVP V1a receptor (V1aR) in the brain. Social behavior often differs across development and between the sexes, yet our understanding
Publikováno v:
Hayashi, M, Inagaki, A, Novak, I & Matsuda, H 2016, ' The adenosine A 2B receptor is involved in anion secretion in human pancreatic duct Capan-1 epithelial cells ', Pfluegers Archiv, vol. 468, no. 7, pp. 1171-1181 . https://doi.org/10.1007/s00424-016-1806-9
Europe PubMed Central
Pflugers Archiv
Europe PubMed Central
Pflugers Archiv
Adenosine modulates a wide variety of biological processes via adenosine receptors. In the exocrine pancreas, adenosine regulates transepithelial anion secretion in duct cells and is considered to play a role in acini-to-duct signaling. To identify t
Autor:
Monika Ptach, Jiřina Slaninová, Anna Kwiatkowska, Adam Prahl, Bernard Lammek, Lenka Borovičková
Publikováno v:
Amino Acids
In this study we present the synthesis and some pharmacological properties of fourteen new analogues of neurohypophyseal hormones conformationally restricted in the N-terminal part of the molecule. All new peptides were substituted at position 2 with
Publikováno v:
Journal of Orthopaedic Surgery and Research
Background Epidural fibrosis often causes serious complications in patients after lumbar laminectomy and discectomy and is associated with the proliferation of fibroblasts. Suramin is known to have an obvious inhibitory effect on the coactions of man
Autor:
Katrin S. Lips, Martin Fronius, Jürgen Lohmeyer, Zbigniew Zaslona, Uwe Pfeil, Hjalmar Kurzen, Gitte Jositsch, Wolfgang Kummer, Zbigniew Mikulski, Petra Hartmann, Wolfgang Clauss, Veronika Grau
Publikováno v:
Respiratory Research
Respiratory Research, Vol 11, Iss 1, p 133 (2010)
Respiratory Research, Vol 11, Iss 1, p 133 (2010)
Background Nicotinic acetylcholine receptors (nAChR) have been identified on a variety of cells of the immune system and are generally considered to trigger anti-inflammatory events. In the present study, we determine the nAChR inventory of rat alveo
Publikováno v:
Journal of Neuroinflammation
Background Tamoxifen, a selective estrogen receptor modulator, has successfully been used to treat several animal models of brain injury, but the underlying mechanisms remain unclear. This study was undertaken to evaluate the effect of tamoxifen on t
Autor:
Valeria Corradetti, Pasquale Esposito, Chiara Rocca, Francesco Frassoni, Teresa Valsania, Chiara Collesi, Marilena Gregorini, Giulia Bedino, Teresa Rampino, Francesca Bosio, Antonio Dal Canton, Carmelo Libetta, Eleonora Francesca Pattonieri
Publikováno v:
BMC Immunology
Background: In former studies we showed in a rat model of renal transplantation that Mesenchymal Stromal Cells (MSC) prevent acute rejection in an independent way of their endowing in the graft. In this study we investigated whether MSC operate by re