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Autor:
Patricia L. Lockwood, Matthew F. S. Rushworth, Luke Priestley, Nima Khalighinejad, Neil Garrett
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
The decision that it is worth doing something rather than nothing is a core yet understudied feature of voluntary behaviour. Here we study “willingness to act”, the probability of making a response given the context. Human volunteers encountered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c58c9de4a9d4d3eba70875da5655d0
https://ora.ox.ac.uk/objects/uuid:26b443d2-3833-4d65-9d75-f3de5d2d3080
https://ora.ox.ac.uk/objects/uuid:26b443d2-3833-4d65-9d75-f3de5d2d3080
Autor:
Kristina Zec, Roman Fischer, Irina A. Udalova, Tariq E. Khoyratty, Claire Pearson, Hayley L. Eames, Benedikt M. Kessler, Hannah Almuttaqi, Grigory Ryzhakov, Simon Travis, Samuel J. Bullers, Luke Jostins-Dean, Alastair L. Corbin, Sarah Bonham, Zhichao Ai, Dorothée L. Berthold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Interferon regulating factor 5 (IRF5) is a multifunctional regulator of immune responses, and has a key pathogenic function in gut inflammation, but how IRF5 is modulated is still unclear. Having performed a kinase inhibitor library screening in macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8cfb57ebeee917922ddd5935776e62
https://doi.org/10.1038/s41467-021-27038-5
https://doi.org/10.1038/s41467-021-27038-5
Autor:
Martín-Alonso, Mara, Iqbal, Sharif, Vornewald, Pia M., Lindholm, Håvard T., Damen, Mirjam J., Martínez, Fernando, Hoel, Sigrid, Díez-Sánchez, Alberto, Altelaar, Maarten, Katajisto, Pekka, Arroyo, Alicia G., Oudhoff, Menno J., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
17 p.-8 fig.
Smooth muscle is an essential component of the intestine, both to maintain its structure and produce peristaltic and segmentation movements. However, very little is known about other putative roles that smooth muscle cells may have.
Smooth muscle is an essential component of the intestine, both to maintain its structure and produce peristaltic and segmentation movements. However, very little is known about other putative roles that smooth muscle cells may have.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b98826dca588121db8a83fd6e3dd47
http://hdl.handle.net/10261/256789
http://hdl.handle.net/10261/256789
Autor:
Adelino, Talita ?mile Ribeiro, Giovanetti, Marta, Fonseca, Vagner, Xavier, Joilson, Abreu, ?lvaro Salgado de, Nascimento, Valdinete Alves do, Demarchi, Luiz Henrique Ferraz, Oliveira, Marluce Aparecida Assun??o, Silva, Vin?cius Lemos da, Mello, Arabela Leal e Silva de, Cunha, Gabriel Muricy, Santos, Roselene Hans, Oliveira, Elaine Cristina de, Chamon J?nior, Jorge Ant?nio, Iani, Felipe Campos de Melo, Filippis, Ana Maria Bispo de, Abreu, Andr? Luiz de, Jesus, Ronaldo de, Albuquerque, Carlos Frederico Campelo de, Rico, Jairo Mendez, Said, Rodrigo Fabiano do Carmo, Silva, Josc?lio Aguiar, Moura, Noely Fabiana Oliveira de, Leite, Priscila, Frutuoso, L?via Carla Vinhal, Haddad, Simone Kashima, Mart?nez, Alexander, Barreto, Fernanda Khouri, Vazquez, Cynthia Carolina, Cunha, Rivaldo Ven?ncio da, Ara?jo, Emerson Luiz Lima, Tosta, Stephane Fraga de Oliveira, Fabri, Allison de Ara?jo, Chalhoub, Fl?via Lowen Levy, Lemos, Poliana da Silva, Bruycker-Nogueira, Fernanda de, Lichs, Gislene Garcia de Castro, Zardin, Marina Castilho Souza Umaki, Segovia, F?tima Mar?a Cardozo, Gon?alves, Crhistinne Cavalheiro Maymone, Grillo, Zoraida Del Carmen Fernandez, Slavov, Svetoslav Nanev, Pereira, Luiz Augusto, Mendon?a, Ana Fl?via, Pereira, Felicidade Mota, Magalh?es, Jurandy J?nior Ferraz de, Santos J?nior, Agenor de Castro Moreira dos, Lima, Maric?lia Maia de, Nogueira, Rita Maria Ribeiro, G?es-Neto, Arist?teles, Azevedo, Vasco Ariston de Carvalho, Ramalho, Dario Brock, Oliveira, Wanderson Kleber, Macario, Eduardo Marques, Medeiros, Arnaldo Correia de, Pimentel, Victor, Holmes, Edward C, Oliveira, Tulio de, Louren?o, Jos?, Alcantara, Luiz Carlos Junior, Cerqueira, Erenilde Marques de, Graf, Tiago, Ramalho, Walter, Navegantes, Wildo, Reis, Renato Barbosa, Duarte, Clara Guerra, Pereira, Maria Alves, Silva, Paulo Eduardo de Souza da, Souza, Raoni Almeida de, Pauvolid-Corr?a, Alex, Paiva, Anne Aline Pereira de, Fritsch, Hegger Machado, Mares-Guia, Maria Ang?lica, Torres, Maria Celeste, Lima, Maur?cio Teixeira, Sequeira, Patr?cia, Marques, William de Almeida, Jesus, Jorlan Fernandes de, Naveca, Felipe Gomes, Silva, Alessandra Lima, Pinto, Anne Cybelle, Jaiswal, Arun Kumar, Lopes, ?lisson Nogueira, Costa, Francielly Morais Rodrigues da, Quintanilha-Peixoto, Gabriel, Soares, Gilson Carlos, Fonseca, Paula Luize Camargos, Souza, Renan Pedra de, Kato, Rodrigo Bentes, Santos, Rodrigo Profeta Silveira, Tiwari, Sandeep, Nogueira, Wylerson Guimar?es, Santos, Beatriz Senra ?lvares da Silva, Bueno, Bruna Lopes, Siqueira, Isadora Cristina de, Valle, Lourdes Farre, Borba, Melina Mosquera Navarro, Mazzetto, Alix Sandra, Aguiar, Francisco de Assis Ara?jo, Gomes, Irenio da Silva, Abrantes, Jayra Juliana Paiva Alves, Watanabe, Luiz Takao, Rego, Marta Ferreira da Silva, Nardy, Vanessa Brand?o, Aguiar, Shirlei Ferreira de, Santos, Fabiana Cristina Pereira dos, Queiroz, Alice Louize Nunes, Nunes, Bruno Tardelli Diniz, Martins, L?via Car?cio, Nunes, Marcio Roberto Teixeira, Salles, Fl?via Cristina da Silva, Claro, Ingra Morales, Jesus, Jaqueline Goes de, C?ndido, Darlan da Silva, Fabbri, Cintia Marcela, Gonz?lez, Claudia, Sa?z, Lisseth, Chen-Germ?n, Mar?a, Barrera, Jaime Lagos, Ram?rez-Gonz?lez, Jos? Ernesto, Campos, Josefina, Faller, Noelia Morel, Villalobos, Marta Eugenia V?quez, Kaslin, Roberto, Cisneros, Silvia Paola Salgado, Aburjaile, Fl?via Figueira, Amaral, Carolina Dourado, Freire, Danielle Bandeira Costa de Sousa, Cruz, Laura Nogueira, Mattos, Daniel, Landeira, Leandro Ferreira Lopes, Menezes, Mariane Talon de, Orioli, Ieda Maria, Ferraz, Ariane Coelho, Oliveira, Daiane Teixeira de, Reis, Alexandre Barbosa, Cota, Renata Guerra de S?, Bezerra, Rafael dos Santos, Falc?o, Melissa Barreto, Carvalho, Rodrigo Dias de Oliveira
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC
Nature Communications
Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC
Brazil experienced a large dengue virus (DENV) epidemic in 2019, highlighting a continuous struggle with effective control and public health preparedness. Using Oxford Nanopore sequencing, we led field and classroom initiatives for the monitoring of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d9eebd7e94a174146febab75025bfc
https://ora.ox.ac.uk/objects/uuid:cdb29255-18ff-4667-a6cd-adbc4a25d33d
https://ora.ox.ac.uk/objects/uuid:cdb29255-18ff-4667-a6cd-adbc4a25d33d
Autor:
Robert E MacLaren, Harry O Orlans, Michelle E. McClements, Alun R. Barnard, Cristina Martinez-Fernandez de la Camara
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Rhodopsin (RHO) gene mutations are a common cause of autosomal dominant retinitis pigmentosa (ADRP). The need to suppress toxic protein expression together with mutational heterogeneity pose challenges for treatment development. Mirtrons are atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d763a884a5b2e72b00d42ebcc5cfa5
https://ora.ox.ac.uk/objects/uuid:d5255281-048a-4e08-ac4a-f0defc618a77
https://ora.ox.ac.uk/objects/uuid:d5255281-048a-4e08-ac4a-f0defc618a77
Autor:
Yun-Ru Chen, Lee-Way Jin, Yu Sheng Fang, Yao Hsiang Shih, Ling Hsien Tu, Wei Wei Chang, Yeh Tung Lin, Kiruthika Ganesan, Pao Sheng Chang, Ting Yu Chang
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
TDP-43 inclusions are found in many Alzheimer’s disease (AD) patients presenting faster disease progression and greater brain atrophy. Previously, we showed full-length TDP-43 forms spherical oligomers and perturbs amyloid-β (Aβ) fibrillization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4187131f111a6378df3c13344a8d36c5
https://ora.ox.ac.uk/objects/uuid:fb36f9aa-6fd0-4b55-b6a0-09c5d1ec070c
https://ora.ox.ac.uk/objects/uuid:fb36f9aa-6fd0-4b55-b6a0-09c5d1ec070c
Autor:
Marta Vilalta, Adam J. Krieg, Caiyun G. Li, Eui Jung Moon, Amato J. Giaccia, Jen-Tsan Chi, Edward E. Graves, Jacob G. Kirkland, Stephano S. Mello, Anh N. Diep, Marjan Rafat, Yu Miao, Edward L. LaGory, Laura D. Attardi, Kaushik N. Thakkar, Laura Castellini, Ik Jae Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574b64acea8911667a49665037069c39
https://doi.org/10.1038/s41467-021-24631-6
https://doi.org/10.1038/s41467-021-24631-6
Autor:
Fernando Ramos Lopez, Alison M. Lawrie, Nguyen Tran, Amy Flaxman, Adrian V. S. Hill, P M Folegatti, M Bittaye, Lorena Preciado-Llanes, Sasha R. Azar, Ian D. Poulton, R Makinson, Young Chan Kim, Shannan L. Rossi, Katie J. Ewer, Kate Harrison, Rafael K. Campos, D Jenkin, Jonathan Sheridan, Mark Tilley, Eleanor Berrie, Arturo Reyes-Sandoval, Rachel Roberts, D Bellamy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Chikungunya virus (CHIKV) is a reemerging mosquito-borne virus that causes swift outbreaks. Major concerns are the persistent and disabling polyarthralgia in infected individuals. Here we present the results from a first-in-human trial of the candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731cd1326dad67f34434a3b0adc4bdef
https://ora.ox.ac.uk/objects/uuid:392ef680-ccfc-4eee-a066-312181e544c7
https://ora.ox.ac.uk/objects/uuid:392ef680-ccfc-4eee-a066-312181e544c7
Autor:
Rushika C. Wirasinha, Hong Ying Teh, Adam E. Handel, Stephen R. Daley, Benoit Roch, Saulius Žuklys, Stuart H. Orkin, Thomas Barthlott, Jean-Pierre de Villartay, Katrin Hafen, Georg A. Holländer
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Thymic T cell development and T cell receptor repertoire selection are dependent on essential molecular cues provided by thymic epithelial cells (TEC). TEC development and function are regulated by their epigenetic landscape, in which the repressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9e2439df69c3a497fbd82be6559f2d
https://doi.org/10.1038/s41467-021-24158-w
https://doi.org/10.1038/s41467-021-24158-w
Autor:
Saad Jbabdi, Marianne Aspbury, Fiona Moultrie, Matteo Bastiani, Richard Rogers, Roshni Mansfield, Rebeccah Slater, Eugene P. Duff, Sean P. Fitzgibbon, Luke Baxter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Understanding the neurophysiology underlying neonatal responses to noxious stimulation is central to improving early life pain management. In this neonatal multimodal MRI study, we use resting-state and diffusion MRI to investigate inter-individual v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd01292175d83ab16a49c6297c81516
https://ora.ox.ac.uk/objects/uuid:435d2049-c77f-4856-85dc-80880e440739
https://ora.ox.ac.uk/objects/uuid:435d2049-c77f-4856-85dc-80880e440739