Zobrazeno 1 - 9
of 9
pro vyhledávání: ''
Autor:
Bernd J. Pichler, Jörg Köhl, Matthias Mezger, Ruslan Hlushchuk, Oliver Borst, Jeanette Erdmann, Triantafyllos Chavakis, David Haberthür, Roza Meyer-Saraei, Harald F. Langer, Christian M. Karsten, Henry Nording, Johannes Patzelt, Frederic Emschermann, Kai Knoepp, Robert Feil, Manuela Sauter, Ingo Eitel, Admar Verschoor, Moritz Meusel, Philipp von Hundelshausen, Reinhard Sauter, Emmanouil Chavakis, Anne Nording, Daniel Sedding, Lasse Baron, Meinrad Gawaz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
Nording, Henry; Baron, Lasse; Haberthür, David; Emschermann, Frederic; Mezger, Matthias; Sauter, Manuela; Sauter, Reinhard; Patzelt, Johannes; Knoepp, Kai; Nording, Anne; Meusel, Moritz; Meyer-Saraei, Roza; Hlushchuk, Ruslan; Sedding, Daniel; Borst, Oliver; Eitel, Ingo; Karsten, Christian M.; Feil, Robert; Pichler, Bernd; Erdmann, Jeanette; ... (2021). The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets. Nature Communications, 12(1), p. 3352. Springer Nature 10.1038/s41467-021-23499-w
Nature Communications
Nording, Henry; Baron, Lasse; Haberthür, David; Emschermann, Frederic; Mezger, Matthias; Sauter, Manuela; Sauter, Reinhard; Patzelt, Johannes; Knoepp, Kai; Nording, Anne; Meusel, Moritz; Meyer-Saraei, Roza; Hlushchuk, Ruslan; Sedding, Daniel; Borst, Oliver; Eitel, Ingo; Karsten, Christian M.; Feil, Robert; Pichler, Bernd; Erdmann, Jeanette; ... (2021). The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets. Nature Communications, 12(1), p. 3352. Springer Nature 10.1038/s41467-021-23499-w
Nature Communications
Platelets contribute to the regulation of tissue neovascularization, although the specific factors underlying this function are unknown. Here, we identified the complement anaphylatoxin C5a-mediated activation of C5a receptor 1 (C5aR1) on platelets a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4266211e357741350719b6b9b7c3e23
Autor:
Daniel Brigger, Rahel Ruppli, Pascal Guntern, Theodore S. Jardetzky, Alexander Eggel, Svetlana S. Tarchevskaya, Silke Kleinboelting, Noemi Zbären, Pascal Gasser, Christoph Heusser
Publikováno v:
Gasser, Pascal; Tarchevskaya, Svetlana S; Guntern, Pascal Martin; Brigger, Daniel; Ruppli, Rahel; Zbären, Noemi; Kleinboelting, Silke; Heusser, Christoph; Jardetzky, Theodore S; Eggel, Alexander (2020). The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab. Nature Communications, 11(1), p. 165. Springer Nature 10.1038/s41467-019-13815-w
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Targeting of immunoglobulin E (IgE) represents an interesting approach for the treatment of allergic disorders. A high-affinity monoclonal anti-IgE antibody, ligelizumab, has recently been developed to overcome some of the limitations associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724f87e01b9a61768d0b922f9bc49897
https://boris.unibe.ch/138505/1/s41467-019-13815-w.pdf
https://boris.unibe.ch/138505/1/s41467-019-13815-w.pdf
Autor:
Tatsuo Masuda, Jun Hirata, Tomohiro Handa, Kyuto Sonehara, Kenichi Yamamoto, Yoshinori Tanino, Saori Sakaue, Meiko Takahashi, Takashi Yamada, Masaru Suzuki, Hiromasa Inoue, Konosuke Morimoto, Takafumi Suda, Toru Arai, Keisuke Tomii, Atsushi Kumanogoh, Hidenori Ibata, Fumihiko Matsuda, Yoshikazu Inoue, Koh Nakata, Nobuyuki Hizawa, Toshiyuki Kato, Yuichi Maeda, Hideki Mochizuki, Kiminobu Tanizawa, Kazuyoshi Imaizumi, Ken Suzuki, Masaki Watanabe, Naoya Takeda, Ryushi Tazawa, Hiroshi Kida, Satoshi Konno, Yasuhiro Goto, Toshihiro Kishikawa, Haruyuki Ishii, Masahiro Takaki, Koshi Yokomura, Manabu Ishida, Atsushi Nakagawa, Masaki Hirose, Takashi Matsui, Tomomitsu Hirota, Takefumi Nikaido, Satoru Miyawaki, Satoru Ito, Etsuro Yamaguchi, Taizou Hirano, Toshinori Takada, Shogo Dofuku, Yasuomi Satake, Shinya Ohkouchi, Kotaro Ogawa, Takuro Nii, Tomoyuki Fujisawa, Toshio Ichiwata, Mayumi Tamari, Yukinori Okada
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
Pulmonary alveolar proteinosis (PAP) is a devastating lung disease caused by abnormal surfactant homeostasis, with a prevalence of 6–7 cases per million population worldwide. While mutations causing hereditary PAP have been reported, the genetic ba
Autor:
Iori Itagaki, Masatsugu Ema, Hideaki Tsuchiya, Hiroyuki Izumi, Akihiro Kawauchi, Shinji Kume, Chizuru Iwatani, Ikuo Kawamoto, Teppei Iwakiri, Tomoyuki Tsukiyama, Koji Fukuda, Takahiro Nakagawa, Kenichi Kobayashi, Saori Nishio, Yasunari Seita, Kahoru Kitajima, Masataka Nakaya, Shinichiro Nakamura, Hiroshi Maegawa, Jun Matsushita, Ryuichi Nishinakamura
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Autosomal dominant polycystic kidney disease (ADPKD) caused by PKD1 mutations is one of the most common hereditary disorders. However, the key pathological processes underlying cyst development and exacerbation in pre-symptomatic stages remain unknow
Autor:
Javier Rangel-Moreno, Shabaana A. Khader, Kristin L. Griffiths, Maxim N. Artyomov, Terry D. Connell, Mushtaq Ahmed, Shibali Das, Jay K. Kolls, Kelly D. Moynihan, William Horne, Radha Gopal, Darrell J. Irvine
Publikováno v:
Nature
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
The development of a tuberculosis (TB) vaccine that induces sterilizing immunity to Mycobacterium tuberculosis infection has been elusive. Absence of sterilizing immunity induced by TB vaccines may be due to delayed activation of mucosal dendritic ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0039a941640f2f8f9ece4994982f1a14
http://hdl.handle.net/1721.1/107719
http://hdl.handle.net/1721.1/107719
Autor:
Thabet, Khaled, Asimakopoulos, Anastasia, Shojaei, Maryam, Romero Gomez, Manuel, Mangia, Alessandra, Irving, William L., Berg, Thomas, Dore, Gregory J., Grønbæk, Henning, Sheridan, David, Abate, Maria Lorena, Bugianesi, Elisabetta, Weltman, Martin, Mollison, Lindsay, Cheng, Wendy, Riordan, Stephen, Fischer, Janett, Spengler, Ulrich, Nattermann, Jacob, Wahid, Ahmed, Rojas, Angela, White, Rose, Douglas, Mark W., Mcleod, Duncan, Powell, Elizabeth, Liddle, Christopher, Van Der Poorten, David, George, Jacob, Eslam, Mohammed, Gallego Duran, Rocio, Applegate, Tanya, Bassendine, Margaret, Rosso, Chiara, Mezzabotta, Lavinia, Leung, Reynold, Malik, Barbara, Matthews, Gail, Grebely, Jason, Fragomeli, Vincenzo, Jonsson, Julie R., Santaro, Rosanna
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Thabet, K, Asimakopoulos, A, Shojaei, M, Romero-Gomez, M, Mangia, A, Irving, W L, Berg, T, Dore, G J, Grønbæk, H, Sheridan, D, Abate, M L, Bugianesi, E, Weltman, M, Mollison, L, Cheng, W, Riordan, S, Fischer, J, Spengler, U, Nattermann, J, Wahid, A, Rojas, A, White, R, Douglas, M W, McLeod, D, Powell, E, Liddle, C, van der Poorten, D, George, J, Eslam, M & International Liver Disease Genetics Consortium 2016, ' MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C ', Nature Communications, vol. 7, pp. 12757 . https://doi.org/10.1038/ncomms12757
Nature Communications
instname
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Thabet, K, Asimakopoulos, A, Shojaei, M, Romero-Gomez, M, Mangia, A, Irving, W L, Berg, T, Dore, G J, Grønbæk, H, Sheridan, D, Abate, M L, Bugianesi, E, Weltman, M, Mollison, L, Cheng, W, Riordan, S, Fischer, J, Spengler, U, Nattermann, J, Wahid, A, Rojas, A, White, R, Douglas, M W, McLeod, D, Powell, E, Liddle, C, van der Poorten, D, George, J, Eslam, M & International Liver Disease Genetics Consortium 2016, ' MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C ', Nature Communications, vol. 7, pp. 12757 . https://doi.org/10.1038/ncomms12757
Nature Communications
International Liver Disease Genetics Consortium.
Cirrhosis likely shares common pathophysiological pathways despite arising from a variety of liver diseases. A recent GWAS identified rs641738, a polymorphism in the MBOAT7 locus, as being associa
Cirrhosis likely shares common pathophysiological pathways despite arising from a variety of liver diseases. A recent GWAS identified rs641738, a polymorphism in the MBOAT7 locus, as being associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf9d66868db3b23663b723930b3f6f7
http://hdl.handle.net/10261/198342
http://hdl.handle.net/10261/198342
Autor:
Emi Yamasaki, Tetsuhiro Kikuchi, Sayuki Takara, Hirohito Ishigaki, Hisashi Doi, Daisuke Doi, Kazumasa Ogasawara, Asuka Morizane, Hiroshi Mizuma, Hirotaka Onoe, Keisuke Okita, Matthew F. Glasser, Takashi Shiina, Shinya Yamanaka, Yasushi Itoh, Aya Mawatari, Takuya Hayashi, Jun Takahashi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
The banking of human leukocyte antigen (HLA)-homozygous-induced pluripotent stem cells (iPSCs) is considered a future clinical strategy for HLA-matched cell transplantation to reduce immunological graft rejection. Here we show the efficacy of major h
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Programmed cell death has a crucial role in various biological events, including developmental morphogenesis. Recent evidence indicates that necrosis contributes to programmed cell death in addition to apoptosis, but it is unclear whether necrosis ac
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications
Nature communications, vol. 8, no. 1, pp. 367
Nature Communications
Nature communications, vol. 8, no. 1, pp. 367
Lymphatic growth (lymphangiogenesis) within lymph nodes functions to promote dendritic cell entry and effector lymphocyte egress in response to infection or inflammation. Here we demonstrate a crucial role for lymphotoxin-beta receptor (LTβR) signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d45f9ffda7cc71e701b66c38238af4e
https://infoscience.epfl.ch/record/231735
https://infoscience.epfl.ch/record/231735