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Autor:
Tomoaki Oda, Masako Matsumoto, Chizuko Yaguchi, Naoaki Tamura, Toshiyuki Uchida, Hiroaki Itoh, Yoshimasa Horikoshi, Naohiro Kanayama, Kazunao Suzuki, Divyanu Jain, Naomi Furuta-Isomura, Megumi Narumi, Yukiko Kohmura-Kobayashi, Kenta Kawai
Publikováno v:
Journal of Thrombosis and Thrombolysis. 53(1):208-212
Pulmonary thromboembolism (PTE) is one of the leading causes of maternal mortality. We previously reported that possible contamination of amniotic fluid (AF) into maternal circulation accelerated thrombin production and activated platelet function in
Autor:
Jan-Stefan van der Walt, Joji Mori, Takahiro Nakayama, Kenichi Inoue, Yoshinori Ito, George W. Sledge, Yasuo Miyoshi, Tsutomu Kawaguchi, Masato Takahashi, Yoshinori Tanizawa, Masakazu Toi, Antonio Llombart-Cussac, Norikazu Masuda, Hiroji Iwata, Hirofumi Mukai, Sachi Sakaguchi
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background This was a Japanese subpopulation analysis of MONARCH 2, a double-blind, randomized, placebo-controlled, phase 3 study of abemaciclib plus fulvestrant in patients with hormone receptor-positive, human epidermal growth factor receptor 2-neg
Autor:
Kelvin Chow, Qiang Zhang, Stefan K. Piechnik, Matthew K. Burrage, Rajkumar Soundarajan, Mayooran Shanmuganathan, Iulia A. Popescu, Vanessa M Ferreira, Stefan Neubauer, Evan Hann
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Stress and rest T1-mapping may assess for myocardial ischemia and extracellular volume (ECV). However, the stress T1 response is method-dependent, and underestimation may lead to misdiagnosis. Further, ECV quantification may be affected by time, as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3dc3c6aeb86dc9e08bc18ed7e5d4fc6
https://ora.ox.ac.uk/objects/uuid:a0648fbc-6319-48fc-8dd9-9884bb363008
https://ora.ox.ac.uk/objects/uuid:a0648fbc-6319-48fc-8dd9-9884bb363008
Autor:
Kaito Shibata, Junichi Kawakami, Satoshi Hirakawa, Hiroyuki Mineta, Seiji Hosokawa, Koji Suzuki, Takafumi Naito
Publikováno v:
Cancer Chemotherapy and Pharmacology. 87(4):555-565
Purpose: Cetuximab inhibits epidermal growth factor receptor (EGFR) signaling in cancer and skin cells, thereby inducing anti-cancer effects and skin disorders. The present study aimed to evaluate the relationships between serum cetuximab and EGFR-re
Autor:
Ben Yang, Ema Ilijic, Kristen A. Stout, José López-Barneo, David L. Wokosin, Michael G. Kaplitt, Jaime N. Guzman, Enrico Zampese, D. James Surmeier, Lin Gao, Paul T. Schumacker, Patricia González-Rodríguez, Mihaela Stavarache, Tatiana Tkatch
Publikováno v:
Nature
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Loss of functional mitochondrial complex I (MCI) in the dopaminergic neurons of the substantia nigra is a hallmark of Parkinson’s disease1. Yet, whether this change contributes to Parkinson’s disease pathogenesis is unclear2. Here we used interse
Autor:
Erika Cvetko, Maxine M. Kuroda, Vesna Mrak, Tatjana Stopar Pintaric, Liljana Markova, Simon Horvat, Admir Hadžić, Nejc Umek
Publikováno v:
BMC veterinary research, vol. 16, 247, 2020.
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-8 (2020)
BMC Veterinary Research
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-8 (2020)
BMC Veterinary Research
Background Diabetes mellitus and the associated neuropathic complications have become a steadily increasing global health burden. Diabetic patients are estimated to require surgery at least twice as often as nondiabetic patients. Neuropathy may chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd94c1252c8c56c394f5e5a6185b0a81
https://repozitorij.uni-lj.si/Dokument.php?id=145646&dn=
https://repozitorij.uni-lj.si/Dokument.php?id=145646&dn=
Autor:
Ring, A., Battisti, N.M.L., Reed, M.W.R., Herbert, E., Morgan, J.L., Bradburn, M., Walters, S.J., Collins, K.A., Ward, S.E., Holmes, G.R., Burton, Maria, Lifford, K., Edwards, A., Robinson, T.G., Martin, C., Chater, T., Pemberton, K.J., Brennan, A., Cheung, K.L., Todd, A., Audisio, R.A., Wright, J., Simcock, R., Green, T., Revell, D., Gath, J., Horgan, K., Holcombe, C., Winter, M.C., Naik, J., Parmeshwar, R., Gosney, M.A., Hatton, M.Q., Thompson, A.M., Wyld, L., Collins, K., Ward, S., Holmes, G., Morgan, J., Walters, S., Burton, M., Brain, K., Robinson, T., Pemberton, K., Shrestha, A., Nettleship, A., Richards, P., Harder, H., Audisio, R., Murray, C., Thomson, A.M., Gosney, M., Hatton, M., Armitage, F., Patnick, J., Revill, D., Winter, M.
Publikováno v:
British Journal of Cancer
Background Chemotherapy improves outcomes for high risk early breast cancer (EBC) patients but is infrequently offered to older individuals. This study determined if there are fit older patients with high-risk disease who may benefit from chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed056944ecd27827ab3bd963813fe40
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
Autor:
Dirkje W. Sommeijer, Matthew T. Seymour, Lianne Koens, Cornelis J. A. Punt, Sanne ten Hoorn, David Fisher, Tim Maughan, Louis Vermeulen, Faye Elliott, Anne Trinh, Phil Quirke, Susan D. Richman, Jenny F. Seligmann, Tim R. de Back, Richard Adams
Publikováno v:
British Journal of Cancer
British journal of cancer, 125(8), 1080-1088. Nature Publishing Group
British journal of cancer, 125(8), 1080-1088. Nature Publishing Group
Background Patient selection for addition of anti-EGFR therapy to chemotherapy for patients with RAS and BRAF wildtype metastatic colorectal cancer can still be optimised. Here we investigate the effect of anti-EGFR therapy on survival in different c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329765bd38bc4fb86b004b51f8c16428
https://eprints.whiterose.ac.uk/176152/6/s41416-021-01477-9.pdf
https://eprints.whiterose.ac.uk/176152/6/s41416-021-01477-9.pdf
Autor:
Sinisa Savic, Elton J R Vasconcelos, James A. Poulter, Reuben Tooze, Mark Kacar, Rainer Doffinger, Michael F. McDermott, Samuel Lara-Reyna
Publikováno v:
Journal of clinical immunology, vol. 41, no. 2, pp. 441-457, 2021.
Journal of Clinical Immunology
Journal of Clinical Immunology
Biallelic mutations in SLC29A3 cause histiocytosis-lymphadenopathy plus syndrome, also known as H syndrome (HS). HS is a complex disorder, with ~ 25% of patients developing autoinflammatory complications consisting of unexplained fevers, persistently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c33f215279ad04a3994775ec05b5c29
https://dirros.openscience.si/IzpisGradiva.php?id=13870
https://dirros.openscience.si/IzpisGradiva.php?id=13870
Autor:
James L. Thorne, Melina C. Teske, Robyn V. Broad, Andrew M. Hanby, Laura M. Wastall, Stacey J. Jones, Thomas A. Hughes
Publikováno v:
British Journal of Cancer
Background Triple negative breast cancers (TNBC) have poor prognoses despite aggressive treatment with cytotoxic chemotherapy. Cancer-associated fibroblasts (CAFs) are prominent in tumour stroma. Our hypothesis was that CAFs modulate chemotherapy sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027115557c95f3f47f1ecb119dec9f3d