Zobrazeno 1 - 10
of 249
pro vyhledávání: ''
Autor:
Jan-Stefan van der Walt, Joji Mori, Takahiro Nakayama, Kenichi Inoue, Yoshinori Ito, George W. Sledge, Yasuo Miyoshi, Tsutomu Kawaguchi, Masato Takahashi, Yoshinori Tanizawa, Masakazu Toi, Antonio Llombart-Cussac, Norikazu Masuda, Hiroji Iwata, Hirofumi Mukai, Sachi Sakaguchi
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background This was a Japanese subpopulation analysis of MONARCH 2, a double-blind, randomized, placebo-controlled, phase 3 study of abemaciclib plus fulvestrant in patients with hormone receptor-positive, human epidermal growth factor receptor 2-neg
Autor:
Mara Ferrandi, Daniele Cusi, Tzung-Dau Wang, Patrizia Ferrari, Roberto Bigazzi, Jan A. Staessen, Lit Fui Lau, Kang Ling Wang, Chern En Chiang, Giuseppe A. Scioli, Giuseppe Bianchi, Nicola Glorioso, Li Xiaoyi, Chiara Lanzani, Silvio Cavuto, Paolo Manunta, Lorena Citterio
Publikováno v:
The Pharmacogenomics Journal
We compared a standard antihypertensive losartan treatment with a pharmacogenomics-guided rostafuroxin treatment in never-treated Caucasian and Chinese patients with primary hypertension. Rostafuroxin is a digitoxigenin derivative that selectively di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc25333df3ddbc5bf4c703ee494ece4d
Autor:
Ana Abril-Molina, María Esteban-Molina, Andrea Ferreiro-Marzal, Esther Ocete-Hita, Francesca Perin, Cristina Fernandez-Guerrero, Jose María Gómez-Luque
Publikováno v:
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Drugs in R&D
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Universidad de Granada (UGR)
Drugs in R&D
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Trial registry number: EudraCT 2012-005310-19.
Key Points A randomised controlled trial was conducted to test the hypothesis that preoperative infusion of levosimendan would decrease myocardial injury biomarkers (troponin I and B-type natriureti
Key Points A randomised controlled trial was conducted to test the hypothesis that preoperative infusion of levosimendan would decrease myocardial injury biomarkers (troponin I and B-type natriureti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3ab16f9159641f6c2e7c741d85a378
http://hdl.handle.net/10481/66486
http://hdl.handle.net/10481/66486
Autor:
Anne Cooper, Emma Bedson, Christopher A. Miller, Fozia Z Ahmed, Josephine H. Naish, Helen Eccleson, Simon G. Williams, Gavin A. Lewis, Paula R Williamson, Theresa McDonagh, Beatriz Duran Jimenez, Rajavarma Viswesvaraiah, Colin Cunnington, Stuart D. Russell, Dannii Clayton, Susanna Dodd, Erik B. Schelbert, Stefan Neubauer
Publikováno v:
Lewis, G, Schelbert, E B, Naish, J, Bedson, E, Dodd, S, Eccleson, H, Clayton, D, Duran-Jimenez, B, McDonagh, T, Williams, S G, Cooper, A, Cunnington, C, Ahmed, F Z, Viswesvaraiah, R, Russell, S, Neubauer, S, Williamson, P & Miller, C 2019, ' Pirfenidone in Heart Failure With Preserved Ejection Fraction-Rationale and Design of the PIROUETTE Trial ', Cardiovascular Drugs and Therapy . https://doi.org/10.1007/s10557-019-06876-y
Cardiovascular Drugs and Therapy
Cardiovascular Drugs and Therapy
Background The PIROUETTE (PIRfenidOne in patients with heart failUre and preserved lEfT venTricular Ejection fraction) trial is designed to evaluate the efficacy and safety of the anti-fibrotic pirfenidone in patients with chronic heart failure and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91d9e33759119a9e112a75e1b6a6170
https://doi.org/10.1007/s10557-019-06876-y
https://doi.org/10.1007/s10557-019-06876-y
Autor:
López-Cedrún, José, Videla, Sebastián, Burgueño, Miguel, Juárez, Inma, Aboul-Hosn Centenero, Samir Carlos, Martín-Granizo, Rafael, Grau, Joan, Puche, Miguel, Gil-Diez, José-Luis, Hueto Madrid, Juan Antonio, vaqué, anna, Sust, Mariano, Plata-Salamán, Carlos, Monner, Antoni, Co-Crystal of Tramadol-Celecoxib Team
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Drugs in R&D
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Universidad de Barcelona
Drugs in R&D
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Background Co-crystal of tramadol–celecoxib (CTC), containing equimolar quantities of the active pharmaceutical ingredients (APIs) tramadol and celecoxib (100 mg CTC = 44 mg rac–tramadol hydrochloride and 56 mg celecoxib), is a novel API-API co-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d803e9ea6e236793dba1ad86014c973c
http://hdl.handle.net/20.500.12328/3087
http://hdl.handle.net/20.500.12328/3087
Autor:
Neil Poulter, Steven P. Marso, Scott S. Emerson, Bernard Zinman, Alan C. Moses, Ann Marie Ocampo Francisco, John B. Buse, Kajsa Kvist, Kirstine Brown-Frandsen, Martin Lange, Jesper Barner Lekdorf, Thomas R. Pieber, Richard E. Pratley
Publikováno v:
Diabetologia
The Trial Comparing Cardiovascular Safety of Insulin Degludec vs Insulin Glargine in Patients with Type 2 Diabetes at High Risk of Cardiovascular Events (DEVOTE) was a double-blind, randomised, event-driven, treat-to-target prospective trial comparin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aefba1051616034f75038cbedb5dec6
http://hdl.handle.net/10044/1/50409
http://hdl.handle.net/10044/1/50409
DEVOTE 3: Temporal relationships between severe hypoglycaemia, cardiovascular outcomes and mortality
Autor:
Kirstine Brown-Frandsen, Martin Lange, Scott S. Emerson, Darren K. McGuire, Vincent Woo, Thomas R. Pieber, Kajsa Kvist, Steven P. Marso, Simon Heller, John B. Buse, Neil Poulter, Alan C. Moses, Lucine Lehmann, Jesper Barner Lekdorf, Richard E. Pratley, Bernard Zinman
Publikováno v:
Diabetologia
Aims/hypothesis The double-blind Trial Comparing Cardiovascular Safety of Insulin Degludec vs Insulin Glargine in Patients with Type 2 Diabetes at High Risk of Cardiovascular Events (DEVOTE) assessed the cardiovascular safety of insulin degludec. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe3d66997638d4de9ab278430f750db
http://hdl.handle.net/10044/1/50410
http://hdl.handle.net/10044/1/50410
Purpose: Peritoneal inflammation is an important feature in many patients presenting with appendicitis, The contribution of peritoneal nerve fibres to pain experienced after appendicectomy has received little attention. Method: In this prospective do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c254efe6a191adafb2728a7ceeb67a
http://hdl.handle.net/10379/8978
http://hdl.handle.net/10379/8978
Autor:
Peter J. Weiden, Linda Mancione, Mallery G. Mayo, Curt D. Wolfgang, Guangyang Han, Saeed Ahmed, Raymond Manning, J. Michael Ryan
Publikováno v:
CNS Drugs
Background The purpose of this study was to evaluate the safety and effectiveness of iloperidone for the prevention of relapse in schizophrenia. Methods Study subjects were adults with schizophrenia who started on oral open-label iloperidone titrated
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Previous pharmacokinetic studies of the inhaled corticosteroid, fluticasone furoate (FF), and the long-acting, beta2-receptor agonist, vilanterol (VI) have been performed in relatively small populations using non-compartment