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Autor:
Nuria Calzada, Rocío Fuentes-Mateos, Alberto Fernández-Medarde, David Jimeno, Carmela Gómez, Eugenio Santos
Publikováno v:
Cell Death & Disease
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death and Disease, Vol 10, Iss 11, Pp 1-16 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death and Disease, Vol 10, Iss 11, Pp 1-16 (2019)
© The Author(s) 2019.
We reported previously that adult (HRAS−/−; NRAS−/−) double knockout (DKO) mice showed no obvious external phenotype although lower-than-expected numbers of weaned DKO animals were consistently tallied after crossi
We reported previously that adult (HRAS−/−; NRAS−/−) double knockout (DKO) mice showed no obvious external phenotype although lower-than-expected numbers of weaned DKO animals were consistently tallied after crossi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ebe7a57e5e00133e27278a3d3581b1
http://hdl.handle.net/10261/203009
http://hdl.handle.net/10261/203009
Autor:
Edyta Kotlinska-Hasiec, Jolanta Parada-Turska, Patrycja Nowicka-Stazka, Janusz Stazka, Przemyslaw Zadora, Krzysztof Stazka, Wojciech Dabrowski
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis
Increases in plasma kynurenic acid (KYNA) concentration relate to the severity of inflammation. The aim of this study was to analyse changes in plasma KYNA concentration and neutrophil/lymphocyte ratio (NLR) in cardiac surgery patients. Additionally,
Autor:
Torsten Witte
Publikováno v:
Clinical Rheumatology
The prognosis of rheumatoid arthritis has been substantially improved by the treatment with biologics; however, it is still unclear which combination of biological and conventional disease-modifying antirheumatic drugs (DMARDs) is optimal to achieve
Autor:
Svetlana Semenova, Maria Cecilia Garibaldi Marcondes, Howard S. Fox, Nikki Bortell, Timothy Ravasi, Liana Basova
Publikováno v:
Journal of Neuroinflammation
Background Astrocyte activation is one of the earliest findings in the brain of methamphetamine (Meth) abusers. Our goal in this study was to identify the characteristics of the astrocytic acute response to the drug, which may be critical in pathogen
Publikováno v:
Experimental Hematology & Oncology
Background Dysregulation of miRNAs that can act as tumor suppressors or oncogenes can result in tumorigenesis. Previously we demonstrated that miR-199b was significantly downregulated in acute myeloid leukemia (AML) and targets podocalyxin and discoi
Publikováno v:
BMC Pharmacology & Toxicology
Background Pyrogen detection is of utmost importance in pharmaceutical industry, laboratories and health care institutions. As an alternative to the animal-consuming rabbit pyrogen test or Limulus amoebocyte lysate test, the monocyte activation test
Autor:
Sherry A. Chavez, Matthew S. Ripsch, Michael R. Due, Andrew D. Piekarz, Natalie M. Wilson, Rajesh Khanna, Fletcher A. White, Polina Feldman, Hang Yin
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 9, Iss 1, p 200 (2012)
Journal of Neuroinflammation, Vol 9, Iss 1, p 200 (2012)
Background Multiple adverse events are associated with the use of morphine for the treatment of chronic non-cancer pain, including opioid-induced hyperalgesia (OIH). Mechanisms of OIH are independent of opioid tolerance and may involve the morphine m
Autor:
Masato Sato, Toshihiro Nagai, Yoshiki Tani, Miyuki Kobayashi, Joji Mochida, Munetaka Yokoyama
Publikováno v:
Arthritis Research & Therapy
Introduction Angiogenesis is an important factor in the development of osteoarthritis (OA). We investigated the efficacy of bevacizumab, an antibody against vascular endothelial growth factor and an inhibitor of angiogenesis, in the treatment of OA u
Publikováno v:
Stem Cell Research & Therapy
Background The immunomodulatory and anti-inflammatory functions of human gingiva-derived mesenchymal stromal cells (GMSCs) have been demonstrated in contact hypersensitivity (CHS) models; however, their therapeutic effect during the late phase of CHS
Autor:
Dennis Burian, Wei Zhang, David C. Hutchings, J. Leland Booth, Ming-Hui Zou, Jordan P. Metcalf, Wenxin Wu, Xiaoqiu Wang, Houssein Youness, Cory D. Cross, Vicky L. White
Publikováno v:
Respiratory Research
Background Cigarette smoking (CS) is the main risk factor for the development of chronic obstructive pulmonary disease (COPD) and most COPD exacerbations are caused by respiratory infections including influenza. Influenza infections are more severe i