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Publikováno v:
Molecular Imaging and Biology
Objective Fluorophore-labeled contrast imaging agents are moving toward clinical use for a number of applications. The near-infrared dye IRDye 800CW is frequently used in its N-hydroxysuccinamide (NHS) ester form for labeling these agents. Following
Publikováno v:
BMC Complementary and Alternative Medicine
BMC Complementary and Alternative Medicine, Vol 10, Iss 1, p 24 (2010)
BMC Complementary and Alternative Medicine, Vol 10, Iss 1, p 24 (2010)
Background Asclepias curassavica Linn. is a traditional medicinal plant used by tribal people in the western ghats, India, to treat piles, gonorrhoea, roundworm infestation and abdominal tumours. We have determined the protective effect of β-sitoste
Publikováno v:
BMC Complementary and Alternative Medicine
BMC Complementary and Alternative Medicine, Vol 8, Iss 1, p 15 (2008)
BMC Complementary and Alternative Medicine, Vol 8, Iss 1, p 15 (2008)
Background Various human diseases have oxidative stress as one of their component. Many herbs have been reported to exhibit properties that combat oxidative stress through their active constituents such as flavonoids, tannins, phenolic compounds etc.
Autor:
Brendan B. McCormick, Mohan Biyani, Deborah Zimmerman, Susan Lavoie, Simon Leung, Rameez Imtiaz, Jessica Wagner
Publikováno v:
BMC Nephrology
Background Removal of phosphate by peritoneal dialysis is insufficient to maintain normal serum phosphate levels such that most patients must take phosphate binders with their meals. However, phosphate ‘counting’ is complicated and many patients
Autor:
D. Merciris, L. Lepescheux, Roland Blanque, C. Cottereaux, M. Auberval, Philippe Delerive, Dominique Minet, Philippe Clément-Lacroix, Florence Namour
Publikováno v:
BMC Musculoskeletal Disorders
Background Muscle wasting is a hallmark of many chronic conditions but also of aging and results in a progressive functional decline leading ultimately to disability. Androgens, such as testosterone were proposed as therapy to counteract muscle atrop
Autor:
Saeed Murie Al-Shahrani, Vinny Naidoo
Publikováno v:
BMC Veterinary Research
Background Florfenicol, a commonly used veterinary antibiotic, was reported to have caused a severe drop in egg hatchability following its off-label use on a broiler breeder farm in South Africa. According to the pharmacovigilance report, hatchabilit
Publikováno v:
BMC Pharmacology & Toxicology
Background Nonalcoholic steatohepatitis (NASH) is characterized by fat accumulation in the hepatocyte, inflammation, liver cell injury, and varying degrees of fibrosis, and can lead to oxidative stress in liver. Here, we investigated whether Salidros
Publikováno v:
BMC Pharmacology & Toxicology
Background The antimalarial activity of plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone), a naturally occurring naphthoquinone widely distributed in the Plumbaginaceae family has previously been demonstrated in vitro (good activity) and in vivo (wea
Autor:
Peter Stopfer, Rolf Kaiser, Martin Büchert, Matus Studeny, Klaus Mross, Michael Medinger, A. Frost
Publikováno v:
BMC Cancer
Background Nintedanib is a potent, oral angiokinase inhibitor that targets VEGF, PDGF and FGF signalling, as well as RET and Flt3. The maximum tolerated dose of nintedanib was evaluated in a phase I study of treatment-refractory patients with advance
Publikováno v:
BMC Health Services Research
Background Higher dose of vitamin D supplementation 50000 IU is required for those whose serum 25(OH)D levels are 50 nmol/L and below. The increment in serum 25(OH)D though not significantly affected by race, sex or age it is negatively correlated to