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of 88
pro vyhledávání: ''
Autor:
Siim Pauklin, Chao-Hui Chang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Pancreatic cancer (PC) is one of the leading causes of cancer-related death worldwide due to delayed diagnosis and limited treatments. More than 90% of all pancreatic cancers are pancreatic ductal adenocarcinoma (PDAC). Extensive communication betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f3280a797ae02f6b4d5a863e771b4a
https://ora.ox.ac.uk/objects/uuid:67a028d6-db6b-4198-be2f-9d2f28096c0c
https://ora.ox.ac.uk/objects/uuid:67a028d6-db6b-4198-be2f-9d2f28096c0c
Autor:
Graziana Spoto, Michele Vecchio, Angela Maria Amorini, Michelino Di Rosa, Rosalba Parenti, Rosario Gulino, Nunzio Vicario, Grazia Scandura, Federica M. Spitale, Cirino Botta, Simona D’Aprile, G. Leanza, Massimo Gulisano, Giuseppe Lazzarino, Joshua D. Bernstock, Emanuele Buratti, Daniele Tibullo, Cristiana Alberghina, Cesarina Giallongo, Renata Mangione, Miriam Wissam Saab, Robert Zorec, Giovanni Li Volti
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Cell Death and Disease, Vol 12, Iss 7, Pp 1-13 (2021)
Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In order to translationally engage the sonic hedgehog pathway, which is a promising target for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36418db7187bf323d52a6c3c731d3267
http://hdl.handle.net/10447/514377
http://hdl.handle.net/10447/514377
Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells
Autor:
Immo Prinz, Chiara Romagnani, Gilles Gasparoni, Marina Babić, Frederik Heinrich, André Haubner, Adriana Tomic, Mikalai Nienen, Quirin Hammer, Igor Wolfgang Blau, Martin Messerle, Kevin Thurley, Gabriella Pietra, Renate Arnold, Christian Koenecke, Mir-Farzin Mashreghi, Jörn Walter, Pawel Durek, Il-Kang Na, Eva Maria Borst, Timo Rückert, P.G. Hemmati, Josefine Dunst, Jörg Hofmann, Nina Babel
Natural killer (NK) cells are innate lymphocytes that lack antigen-specific rearranged receptors, a hallmark of adaptive lymphocytes. In some people infected with human cytomegalovirus (HCMV), an NK cell subset expressing the activating receptor NKG2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9331561d8c605f86f00af8e8734103ac
https://ora.ox.ac.uk/objects/uuid:a816fc66-a5be-44d7-8a0e-741f9f2f7482
https://ora.ox.ac.uk/objects/uuid:a816fc66-a5be-44d7-8a0e-741f9f2f7482
Autor:
Sushrut M. Pathy, Jose Manuel Mellado-Gil, Young Jae Bahn, Ying E. Zhang, Sushil G. Rane, Ji-Hyeon Lee
Publikováno v:
Cell Death and Disease, Vol 11, Iss 3, Pp 1-15 (2020)
Cell Death & Disease
Cell Death & Disease
Prevailing insulin resistance and the resultant hyperglycemia elicits a compensatory response from pancreatic islet beta cells (β-cells) that involves increases in β-cell function and β-cell mass. However, the sustained metabolic stress eventually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc7b7f5897def87ca026e6c763ff76b
https://hdl.handle.net/10668/3869
https://hdl.handle.net/10668/3869
Autor:
Yuichi Sakamori, Naoki Nakajima, Toyohiro Hirai, Takahiro Tsuji, Akihiko Yoshizawa, Toshi Menju, Hiroaki Ozasa, Hitomi Ajimizu, Hiroshi Date, Hironori Yoshida, Yuto Yasuda, Tomoko Funazo, Masatoshi Yamazoe, Takashi Nomizo, Young Hak Kim
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 3, Pp 1-15 (2020)
Cell Death and Disease, Vol 11, Iss 3, Pp 1-15 (2020)
There have been few advances in the treatment of small-cell lung cancer (SCLC) because of the lack of targets. MCL1, a member of the anti-apoptotic BCL-2 family, may be a treatment target in several cancers, including SCLC. However, whether the expre
Autor:
Miryam Cadenas, María Negrete, Victor M. Victor, Raquel Chapresto-Garzón, Francisco J. Padillo, Elena Navarro-Villarán, Jordi Muntané, María A. Rodríguez-Hernández, Miguel Ángel Gómez-Bravo
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 5, Pp 1-10 (2020)
instname
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 5, Pp 1-10 (2020)
Sorafenib and Regorafenib are the recommended first- and second-line therapies in patients with advanced hepatocellular carcinoma (HCC). Lenvatinib and Cabozantinib have shown non-inferior antitumoral activities compared with the corresponding recomm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae544078e88cc08defb3d5d97a8520d
http://hdl.handle.net/10261/235700
http://hdl.handle.net/10261/235700
Autor:
Ilaria Genovese, Mattia Vicario, Theo Battista, Lucia Barazzuol, Elena Poser, Luciana Mosca, Giuseppina D'Alessandro, Andrea Arena, Marzia Perluigi, Francesco Fazi, Gianni Colotti, Claudia Tito, Flavia Giamogante, Carlotta Giorgi, Andrea Ilari, Vincenzo Sorrentino, Raffaela Cipriani, Tito Calì, Daniela Rossi, Cristina Limatola, Ferdinando Squitieri, Filip Van Petegem, Annarita Fiorillo
Publikováno v:
Cell death and disease 11 (2020). doi:10.1038/s41419-020-03063-y
info:cnr-pdr/source/autori:Genovese I.; Giamogante F.; Barazzuol L.; Battista T.; Fiorillo A.; Vicario M.; D'Alessandro G.; Cipriani R.; Limatola C.; Rossi D.; Sorrentino V.; Poser E.; Mosca L.; Squitieri F.; Perluigi M.; Arena A.; van Petegem F.; Tito C.; Fazi F.; Giorgi C.; Cali T.; Ilari A.; Colotti G./titolo:Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases/doi:10.1038%2Fs41419-020-03063-y/rivista:Cell death and disease/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Cell Death and Disease, Vol 11, Iss 10, Pp 1-18 (2020)
info:cnr-pdr/source/autori:Genovese I.; Giamogante F.; Barazzuol L.; Battista T.; Fiorillo A.; Vicario M.; D'Alessandro G.; Cipriani R.; Limatola C.; Rossi D.; Sorrentino V.; Poser E.; Mosca L.; Squitieri F.; Perluigi M.; Arena A.; van Petegem F.; Tito C.; Fazi F.; Giorgi C.; Cali T.; Ilari A.; Colotti G./titolo:Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases/doi:10.1038%2Fs41419-020-03063-y/rivista:Cell death and disease/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Cell Death and Disease, Vol 11, Iss 10, Pp 1-18 (2020)
Dysregulation of calcium signaling is emerging as a key feature in the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), and targeting this process may be thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee40e1a0ebb07922fb3948fd93a4cff
http://hdl.handle.net/11577/3355009
http://hdl.handle.net/11577/3355009
Autor:
Susumu Inamoto, Yoshiro Itatani, Gen Nishikawa, Jun Nakagawa, Rei Mizuno, Kenji Kawada, Yoshiharu Sakai, Ryotaro Ogawa, Kosuke Toda
Publikováno v:
Cell Death and Disease, Vol 10, Iss 4, Pp 1-13 (2019)
Cell Death & Disease
Cell Death & Disease
Mesenchymal stem cells (MSCs) are recruited from BM to the stroma of developing tumors, where they serve as critical components of the tumor microenvironment by secreting growth factors, cytokines, and chemokines. The role of MSCs in colorectal cance
Autor:
Valentina Massa, Paolo Grazioli, Pablo García-Gutiérrez, Thomas Vaccari, José Antonio Guerrero-Martínez, Mario García-Domínguez, María Ceballos-Chávez, Rosana March-Díaz, Jose C. Reyes, Noelia Luna-Peláez
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Cell Death & Disease
Digital.CSIC. Repositorio Institucional del CSIC
Cell Death and Disease, Vol 10, Iss 8, Pp 1-14 (2019)
instname
Cell Death & Disease
Digital.CSIC. Repositorio Institucional del CSIC
Cell Death and Disease, Vol 10, Iss 8, Pp 1-14 (2019)
Mutations in NIPBL are the major cause of Cornelia de Lange Syndrome (CdLS). NIPBL is the cohesin-loading factor and has recently been associated with the BET (bromodomains and extra-terminal (ET) domain) proteins BRD2 and BRD4. Related to this, a Cd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d3b49b5adfdb4d409a64066c55c58d
Autor:
Roberto Pallini, Pier Giulio Conaldi, Gioacchin Iannolo, Bruno Douradinha, Maria Rita Sciuto, Nicola Cuscino, Lucia Ricci Vitiani, Ruggero De Maria
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 4, Pp 1-10 (2019)
Cell Death and Disease, Vol 10, Iss 4, Pp 1-10 (2019)
Zika virus (ZIKV) is a flavivirus with a marked effect on fetal nervous system development. ZIKV treatment has recently been found to also have a benefit against glioblastoma, a highly aggressive brain tumor with a poor prognosis. The reported data d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c805df5500cadaf68ae6106a6c8b8ae4
http://hdl.handle.net/10807/167055
http://hdl.handle.net/10807/167055