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Publikováno v:
Medical Molecular Morphology. 55(2):85-90
Endometriosis is a benign tumor that affect 6-10% women of reproductive age. To date, it is suggested that the aberrant microRNA (miRNA) expressions play important roles in the pathogenesis of endometriosis. Reviewing the literature, we found nine ov
Publikováno v:
Journal of Human Genetics
Breast cancer is a heterogeneous disease that develops through a multistep process via the accumulation of genetic/epigenetic alterations in various cancer-related genes. Current treatment options for breast cancer patients include surgery, radiother
Autor:
Kaito Shibata, Junichi Kawakami, Satoshi Hirakawa, Hiroyuki Mineta, Seiji Hosokawa, Koji Suzuki, Takafumi Naito
Publikováno v:
Cancer Chemotherapy and Pharmacology. 87(4):555-565
Purpose: Cetuximab inhibits epidermal growth factor receptor (EGFR) signaling in cancer and skin cells, thereby inducing anti-cancer effects and skin disorders. The present study aimed to evaluate the relationships between serum cetuximab and EGFR-re
Autor:
Atakan Tevlek, Lígia R. Rodrigues, Khaliunsarnai Tsogtbaatar, Débora Ferreira, Halil Murat Aydin, Diana Andrade Sousa, Eda Çelik
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Background. Osteosarcoma is a highly malignant bone tumor, most frequently occurring in the rapid bone growth phase. Effective treatment of this disease is hindered by the lack of specific probes for early diagnosis and the fast cancer widespread. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd6507dc62d71f143dc7d267f69b416
Autor:
Tomohiro Miyamoto, Shunsuke Yahiro, Takuya Fujimoto, Ryosuke Kuroda, Takehiko Matsushita, Yohei Kawakami, Toshiyuki Takemori, Ikuo Fujita, Teruya Kawamoto, Kazumichi Kitayama, Shuichi Fujiwara, Tomoyuki Matsumoto, Hitomi Hara, Takahiro Niikura, Naomasa Fukase, Toshihiro Akisue, Kenichiro Kakutani, Masayuki Morishita
Publikováno v:
Clinical & Experimental Metastasis. 37(4):509-517
Soft tissue sarcomas (STSs) are rare heterogeneous malignancies of mesenchymal origin. Pulmonary metastases develop in approximately 50% of the patients with high-grade STS, being the major cause of mortality in patients with metastatic STS. Pulmonar
Autor:
Kristina Zec, Roman Fischer, Irina A. Udalova, Tariq E. Khoyratty, Claire Pearson, Hayley L. Eames, Benedikt M. Kessler, Hannah Almuttaqi, Grigory Ryzhakov, Simon Travis, Samuel J. Bullers, Luke Jostins-Dean, Alastair L. Corbin, Sarah Bonham, Zhichao Ai, Dorothée L. Berthold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Interferon regulating factor 5 (IRF5) is a multifunctional regulator of immune responses, and has a key pathogenic function in gut inflammation, but how IRF5 is modulated is still unclear. Having performed a kinase inhibitor library screening in macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8cfb57ebeee917922ddd5935776e62
https://doi.org/10.1038/s41467-021-27038-5
https://doi.org/10.1038/s41467-021-27038-5
Autor:
Francesca Battaglin, W. Michael Korn, Mohamed E. Salem, Philip A. Philip, Moh’d Khushman, Axel Grothey, Davide Soldato, Wafik S. El-Deiry, Sukeshi Patel Arora, Wu Zhang, Richard M. Goldberg, Joanne Xiu, John L. Marshall, Heinz-Josef Lenz, Martin D. Berger, Madiha Naseem, Alberto Puccini, Ryuma Tokunaga, Anthony F. Shields, Andreas Seeber, Michael J. Hall
Publikováno v:
Puccini, Alberto; Seeber, Andreas; Xiu, Joanne; Goldberg, Richard M; Soldato, Davide; Grothey, Axel; Shields, Anthony F; Salem, Mohamed E; Battaglin, Francesca; Berger, Martin Dave; El-Deiry, Wafik S; Tokunaga, Ryuma; Naseem, Madiha; Zhang, Wu; Arora, Sukeshi Patel; Khushman, Moh'd M; Hall, Michael J; Philip, Philip A; Marshall, John L; Korn, W Michael; ... (2021). Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients. NPJ precision oncology, 5(1), p. 95. Springer Nature 10.1038/s41698-021-00230-y
NPJ Precision Oncology
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
NPJ Precision Oncology
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Lymph nodes (LNs) and distant metastases can arise from independent subclones of the primary tumor. Herein, we characterized the molecular landscape and the differences between LNs, distant metastases and primary colorectal cancers (CRCs). Samples we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef01f3b44d477510a8039ec853eee53
https://boris.unibe.ch/160885/1/41698_2021_Article_230.pdf
https://boris.unibe.ch/160885/1/41698_2021_Article_230.pdf
Autor:
E. Bass, M. Winkler, Hashim U. Ahmed, A Pantovic, Ardeshir R. Rastinehad, Martin J. Connor, Rhian Gabe, Stacy Loeb
Publikováno v:
Prostate Cancer and Prostatic Diseases
Background Multiparametric MRI localizes cancer in the prostate, allowing for MRI guided biopsy (MRI-GB) 43 alongside transrectal ultrasound-guided systematic biopsy (TRUS-GB). Three MRI-GB approaches exist; visual estimation (COG-TB); fusion softwar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefd83ba403417a29a39c843ee6a7cba
http://rimi.imi.bg.ac.rs/bitstream/id/2517/Diagnostic_accuracy_of_magnetic_resonance_pub_2021.pdf
http://rimi.imi.bg.ac.rs/bitstream/id/2517/Diagnostic_accuracy_of_magnetic_resonance_pub_2021.pdf
Publikováno v:
Br J Cancer
NEAT1 is a highly abundant nuclear architectural long non-coding RNA. There are two overlapping NEAT1 isoforms, NEAT1_1 and NEAT1_2, of which the latter is an essential scaffold for the assembly of a class of nuclear ribonucleoprotein bodies called p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bde762ce063b40b9e2f9019c14773ac
https://hdl.handle.net/10037/24685
https://hdl.handle.net/10037/24685
Autor:
Amadou, A., Freisling, H., Jenab, M., Tsilidis, K.K., Trichopoulou, A., Boffetta, P., Van Guelpen, B., Mokoroa, O., Wilsgaard, T., Kee, F., Schöttker, B., Ordóñez-Mena, J.M., Männistö, S., Söderberg, S., Vermeulen, R.C.H., Quirós, J.R., Liao, L.M., Sinha, R., Kuulasmaa, K., Brenner, H., Romieu, I., IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Sub Algemeen Theoretical Physics
Publikováno v:
British Journal of Cancer, 124(11), 1882. Nature Publishing Group
Br J Cancer
Br J Cancer
BACKGROUND: We investigated whether associations between prevalent diabetes and cancer risk are pertinent to older adults and whether associations differ across subgroups of age, body weight status or levels of physical activity. METHODS: We harmonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6d0f1003ec6d68dd57d4e02b0c362e
https://ora.ox.ac.uk/objects/uuid:85426259-76ba-4a69-b8d2-4c310484052f
https://ora.ox.ac.uk/objects/uuid:85426259-76ba-4a69-b8d2-4c310484052f