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Autor:
William W. West, R Thompson, Rajesh R. Kulkarni, Sanjay Muttineni, Edibaldo Silva-Lopez, Vivek Verma
Publikováno v:
BMC Cancer
Background Signs and symptoms of a rapidly enlarging breast mass are not only important for all clinicians to recognize and assess, but also are not uncommon occurrences. We describe a similar but unique case that developed into an enormous, 36 cm ex
Autor:
Kristina Pilekær Sørensen, Mads Thomassen, Martin Bak, Qihua Tan, Torben A Kruse, Anne Vibeke Lænkholm, Martin Jakob Larsen, Mette K. Andersen, Anne-Marie Gerdes
Publikováno v:
Larsen, M J, Thomassen, M, Tan, Q, Lænkholm, A V, Bak, M, Sørensen, K P, Andersen, M K, Kruse, T A & Gerdes, A-M 2014, ' RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families ', B M C Medical Genomics, vol. 7, 9, pp. 9 . https://doi.org/10.1186/1755-8794-7-9
BMC Medical Genomics
BMC Medical Genomics
BACKGROUND: In more than 70% of families with a strong history of breast and ovarian cancers, pathogenic mutation in BRCA1 or BRCA2 cannot be identified, even though hereditary factors are expected to be involved. It has been proposed that tumors wit
Autor:
Lauren M. Zasadil, Mark E. Burkard, Beth A. Weaver, Jennifer Laffin, Ryan A. Denu, Craig Kanugh
Publikováno v:
BMC Cancer
Background Centrosome amplification (CA) has been reported in nearly all types of human cancer and is associated with deleterious clinical factors such as higher grade and stage. However, previous reports have not shown how CA affects cellular differ
Autor:
Adel Denewer, Omar Farouk, Emad-Eldeen Hamed, Ahmad Senbe, Ashraf Khater, Fayez Shehatto, Aiman El-Saed, Mahmoud Mesbah, Sameh Roshdy, Adel Fathi, Essam Attia
Publikováno v:
World Journal of Surgical Oncology
Background Traditionally, conservative breast surgery was contraindicated in centrally located breast tumors, with total mastectomy as the treatment of choice. However, restorations of the central defects by the oncoplastic volume displacement or rep
Autor:
Sharon X. Xie, John T. Farrar, Kannie Chim, Angela DeMichele, Jun J. Mao, Robert E. Gross, Qing S. Li, Carrie Tompkins Stricker
Publikováno v:
BMC Cancer
Background Premature discontinuation of aromatase inhibitors (AIs) in breast cancer survivors compromises treatment outcomes. We aimed to evaluate whether patient-reported joint pain predicts premature discontinuation of AIs. Methods We conducted a r
Autor:
Ari T Vaara, Aaron S. Mansfield, Jukka Vakkila, Päivi Heikkilä, Karl von Smitten, Marjut Leidenius
Publikováno v:
BMC Cancer, Vol 9, Iss 1, p 231 (2009)
BMC Cancer
BMC Cancer
Background There is evidence that the immune systems of patients with breast cancer are dysfunctional. Regulatory T cells (Tregs), and IDO, an immunosuppressive enzyme, are associated with more advanced disease in some cancers and may promote immunol
Autor:
Auli Karhu, Pia Alhopuro, Kati K. Waltering, Lauri A. Aaltonen, Robert Winqvist, Tapio Visakorpi
Publikováno v:
BMC Cancer, Vol 8, Iss 1, p 263 (2008)
BMC Cancer
BMC Cancer
Background MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia.
Autor:
Huan-Xin Lin, Sijuan Huang, Juan Zhou, Feng-Yan Li, Jia-Yuan Sun, Qin Lin, Zhen-Yu He, Han Guo, San-Gang Wu
Publikováno v:
Radiation Oncology (London, England)
Background The purpose of this study was to evaluate the brachial plexus (BP) dose of postmastectomy radiotherapy (PMRT) to the ipsilateral supraclavicular (ISCL) area, and report the characteristics of radiation-induced brachial plexus neuropathy (R
Autor:
Aya Zarif, Dania Hariri, Zeina Nahleh, Mohamad Alameddine, Arafat Tfayli, Yasmin Aridi, Romy Abi Fadel, Maya Khalil, Anas Mugharbel, Farah Naja
Publikováno v:
BMC Complementary and Alternative Medicine
Background Breast cancer patients are increasingly seeking Complementary and Alternative Medicine (CAM) therapies with the hope of alleviating the burden of the disease and improving their quality of life (QOL). The objective of this study was to ass
Publikováno v:
Breast Cancer Research
Introduction Much recent work has focused on hypotheses that very early life exposures influence adult cancer risk. For breast cancer it has been hypothesized that high in utero estrogen exposure may increase risk. Methods We used data from the Carol