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Autor:
Michael S. Toss, Emad A. Rakha, Chitra Joseph, Padmashree C.G. Rida, Andrew R. Green, Ian O. Ellis, Nigel P. Mongan, Mohammed A. Aleskandarany, Ibrahim Alshankyty, Mansour Alsaleem, Sasagu Kurozumi, Angela Ogden, Ritu Aneja
E-cadherin is a tumor suppressor gene in invasive lobular breast cancer. However, a proportion of high-grade ductal carcinoma shows reduced/loss of E-cadherin. In this study, we assessed the underlying mechanisms and molecular implications of E-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4fd096ae4d5a4d6360edf9b34a9f20
https://clok.uclan.ac.uk/34530/1/34530.pdf
https://clok.uclan.ac.uk/34530/1/34530.pdf
Autor:
Rezvan Esmaeili, Hassan Fazilaty, Ali-Akbar Zare, Mehrdad Asghari Estiar, Ali Zekri, Narges Jafarbeik-Iravani, Keivan Majidzadeh-A, Leila Farahmand
Carcinoembryonic antigen (CEA) family members play important roles in malignancies and are introduced as biomarkers in different types of cancers. Among them CEACAM19 (CEAL1) gene, a new member of the CEA family, remains to be fully elucidated. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1808b0df50460e3c4e3fc63b2eb78444
http://hdl.handle.net/10261/308379
http://hdl.handle.net/10261/308379
Autor:
Liisa M. Pelttari, Paula Poikonen-Saksela, Kristiina Aittomäki, Päivi Auvinen, Arja Jukkola-Vuorinen, Sanna Hallamies, Heli Nevanlinna, Johanna Mattson, Carl Blomqvist, Antti Jekunen
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-5 (2017)
BMC Cancer
BMC Cancer
Background Several susceptibility genes have been established for female breast cancer, of which mutations in BRCA1 and especially in BRCA2 are also known risk factors for male breast cancer (MBC). The role of other breast cancer genes in MBC is less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4819e7805611ab5361165ecad3b1625
https://erepo.uef.fi/handle/123456789/5171
https://erepo.uef.fi/handle/123456789/5171
Publikováno v:
Scopus-Elsevier
British Journal of Cancer
British Journal of Cancer
In a retrospective cohort study, the mothers and sisters of 740 breast cancer patients aged under 36 at diagnosis have been studied for mortality and cancer incidence. Significantly increased breast cancer mortality was observed below age 60 (30 deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3f253959f0017a85e8496e09979395
Autor:
Fabio Corradini, Francesco Piva, Riccardo Cellerino, C. Brugiati, R. Bracci, Eva Galizia, Italo Bearzi, Alessandra Viel, L. Belvederesi, Diana Baralle, Francesca Bianchi, Michela Raponi, Cristian Loretelli
Publikováno v:
Familial Cancer
Single base substitutions can lead to missense mutations, silent mutations or intronic mutations, whose significance is uncertain. Aberrant splicing can occur due to mutations that disrupt or create canonical splice sites or splicing regulatory seque
Autor:
Tianfeng Wang, Ai-ping Lu, Yiqiang Liu, Yijun Zhou, Zhaoqing Fan, Tao Ouyang, Yuntao Xie, Jinfeng Li, Yingjian He
Publikováno v:
Breast Cancer Research and Treatment
This study aimed to compare the efficacy and safety aspects of three anthracycline-based regimens as neoadjuvant chemotherapy in primary breast cancer. Five-hundred and one patients with clinical stage I-III invasive breast cancer were randomly assig
Autor:
Rossana Bossi, Jørn Olsen, Manhai Long, Eva Cecilie Bonefeld-Jørgensen, Stine Overvad Fredslund
Publikováno v:
Cancer Causes & Control
Bonefeld-Jørgensen, E C, Long, M, Fredslund, S O, Bossi, R & Olsen, J 2014, ' Breast cancer risk after exposure to perfluorinated compounds in Danish women : a case-control study nested in the Danish National Birth Cohort ', Cancer causes & control : CCC, vol. 25, no. 11, pp. 1439-1448 . https://doi.org/10.1007/s10552-014-0446-7
Bonefeld-Jørgensen, E C, Long, M, Fredslund, S O, Bossi, R & Olsen, J 2014, ' Breast cancer risk after exposure to perfluorinated compounds in Danish women : a case-control study nested in the Danish National Birth Cohort ', Cancer causes & control : CCC, vol. 25, no. 11, pp. 1439-1448 . https://doi.org/10.1007/s10552-014-0446-7
Objective Animal studies have indicated that perfluoroalkylated substances (PFAS) increase mammary fibroadenomas. A recent case–control study in Greenlandic Inuit women showed an association between the PFAS serum levels and breast cancer (BC) risk
Autor:
Agneta Wennman-Larsen, Linnea Kjeldgård, Marie I. Nilsson, Kristina Alexanderson, Lena-Marie Petersson, Kerstin S. Fugl-Meyer, Mariann Olsson
Publikováno v:
Quality of Life Research
PURPOSE: To explore, among women of working age, satisfaction with life as a whole and with different life domains, and its associations with social and health variables, shortly after breast cancer surgery. METHODS: This cross-sectional study includ
Autor:
K. Nowicka, Agata Czarnywojtek, M. Lazizi, Edyta Gurgul, K. Dyrda, A. Car, Marek Ruchała, M. Pelka, Kosma Woliński, N. Bednarek, A. Iqbal, Adam Stangierski
Publikováno v:
Journal of Endocrinological Investigation
Purpose Acromegaly is a chronic disease resulting from pathological oversecretion of growth hormone and subsequently insulin growth factor-1. Several complications of the disease have been reported, including cardiovascular diseases, respiratory diso
Autor:
Agnes Jager, Nyrée Smallenbroek, Caroline M. Seynaeve, Jan C. Drooger, Cynthia Epskamp, Bernadette A M Heemskerk-Gerritsen
Publikováno v:
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 156(3), 557-566. Springer New York
Breast Cancer Research and Treatment, 156(3), 557-566. Springer New York
Treatment with (neo)adjuvant chemotherapy for breast cancer, as currently given, causes cell damage by induction of double-strand DNA breaks. Because BRCA1 and BRCA2 proteins play a role in the repair of DNA damage, the efficacy of (neo)adjuvant chem