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Autor:
Seigo Nakamura, Koichiro Tsugawa, Shinobu Masuda, Takanori Ishida, Masaaki Kawai, Kenjiro Aogi, Ai Tomotaki, Kotaro Iijima, Naoki Niikura, Eriko Tokunaga, Takayuki Kinoshita, Hiroaki Miyata, Akemi Kataoka, Takayuki Iwamoto, Yutaka Tokuda, Keisei Anan, Naoki Hayashi, Hiraku Kumamaru, Hideji Masuoka
Publikováno v:
Breast Cancer Research and Treatment
Purpose The aim of this study was to investigate whether young age at onset of breast cancer is an independent prognostic factor in patients from the Japanese Breast Cancer Registry, after adjustment of known clinicopathological prognostic factors. M
Publikováno v:
Breast Cancer (Tokyo, Japan)
The purpose of this article is to describe the current status and future perspectives of the Japan Breast Cancer Research Group (JBCRG). The JBCRG was organized in 2002, with the following purpose: to plan and promote clinical trials and basic resear
Autor:
Antonio Balestrieri, Roberto Attanasio, Iacopo Chiodini, Franco Grimaldi, Francisco Bandeira, Claudio Marcocci, Andrea Palermo, Valentina Camozzi, S. Cassibba, E. Vignali, Vincenzo Rochira, C. Maria Francucci, Alfredo Scillitani, Laura Gianotti, Bruno Madeo, S. Bonadonna, Rinaldo Guglielmi, Michele Zini, Fabio Vescini, Roberto Cesareo
Publikováno v:
Europe PubMed Central
Journal of Endocrinological Investigation
Journal of Endocrinological Investigation
Treatment of osteoporosis is aimed to prevent fragility fractures and to stabilize or increase bone mineral density. Several drugs with different efficacy and safety profiles are available. The long-term therapeutic strategy should be planned, and th
Autor:
Suhail M. Ali, Yuping Tan, Allan Lipton, Christian F. Singer, Jeffrey S. Larson, Thomas Sherwood, Reinhard Horvat, Gordon Parry, Mojgan Haddad, A. Paquet, Jeff Sperinde, Kim Leitzel, Yolanda Lie, Xueguang Jin, John Winslow, Ahmed Chenna, Weidong Huang, Yining Shi, Joyee Banerjee, Jodi Weidler, Jennifer W. Cook, Wolfgang J. Köstler, Michael Bates, Alicia Newton, Ali Mukherjee, Eva Marie Fuchs, Laurie Goodman, Christos J. Petropoulos, Stephen Williams
Publikováno v:
Breast Cancer Research and Treatment
Trastuzumab is effective in the treatment of HER2/neu over-expressing breast cancer, but not all patients benefit from it. In vitro data suggest a role for HER3 in the initiation of signaling activity involving the AKT–mTOR pathway leading to trast
Autor:
Astri Syse, Gjøril Bergva Aas
Publikováno v:
Journal of Cancer Survivorship. 3(1):66-71
Cancer's impact on family formation in older adulthood is not well described. Marriage rates among older adults were therefore explored.Data on the unmarried Norwegian population aged 45-80 in 1974-2001 (N = 306 000) was retrieved from the Cancer Reg
Publikováno v:
Breast Cancer Research and Treatment
Nanoparticle albumin-bound paclitaxel (nab-paclitaxel) has demonstrated clinical benefit in metastatic breast cancer (MBC) in a randomized phase III trial versus paclitaxel (CA012; N = 454) and in a randomized phase II trial versus docetaxel (CA024;
Autor:
Anke Thomas, Sherko Kümmel, Stefan Paepke, Marion Kiechle-Bahat, Ralf Ohlinger, Nadia Harbeck, Mathias Warm, Volker R. Jacobs
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 133(12):905-916
Several large, well-controlled clinical trials have now established that the aromatase inhibitors (AIs), including letrozole, anastrozole, and exemestane, are more effective than tamoxifen when used as adjuvant endocrine therapy in postmenopausal wom
Autor:
Masayuki Yoshida, Kenichi Sugihara, Takashi Hojo, Hitoshi Tsuda, Nobuko Tamura, Sadako Akashi-Tanaka, Takayuki Kinoshita
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background Ipsilateral breast tumor recurrence (IBTR) after partial breast resection and contralateral breast tumor recurrence (CBTR) have been shown to occur relatively frequently in patients with ductal carcinoma in situ (DCIS). However, there is o
Autor:
John Brasure, John E. Vena, Jo L. Freudenheim, Matthew R. Bonner, Joan M. Dorn, James R. Marhsall, Theodore M. Brasky
Publikováno v:
Cancer Causes & Control. 20(3):369-374
Exposures during early life may affect risk of breast cancer. History of tonsillectomy has recently been associated with risk of several cancers, including cancer of the breast.We conducted a population-based case-control study of women living in Wes
Publikováno v:
Pathology Oncology Research
DNA repair by homologous recombination is one of the main processes of DNA double strand breaks repair. In the present work we performed a case-control study (304 cases and 319 controls) to check an association between the genotypes of the c.-61 G>T