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of 82
pro vyhledávání: ''
Autor:
Miguel Gil-Gil, José A. García-Sáenz, E Dalmau Portulas, Elena García-Martínez, Nuria Ribelles, A. Santaballa Bertran, E. Martínez de Dueñas, I Alvarez-Lopez, Susana Bezares
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Clinical & Translational Oncology
Universidad de Barcelona
Clinical & Translational Oncology
PurposeHormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) requires a therapeutic approach that takes into account multiple factors, with treatment being based on anti-estrogen hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a263cb82f360402dddafab187eefb
http://hdl.handle.net/2445/174389
http://hdl.handle.net/2445/174389
Autor:
Michael S. Toss, Emad A. Rakha, Chitra Joseph, Padmashree C.G. Rida, Andrew R. Green, Ian O. Ellis, Nigel P. Mongan, Mohammed A. Aleskandarany, Ibrahim Alshankyty, Mansour Alsaleem, Sasagu Kurozumi, Angela Ogden, Ritu Aneja
E-cadherin is a tumor suppressor gene in invasive lobular breast cancer. However, a proportion of high-grade ductal carcinoma shows reduced/loss of E-cadherin. In this study, we assessed the underlying mechanisms and molecular implications of E-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4fd096ae4d5a4d6360edf9b34a9f20
https://clok.uclan.ac.uk/34530/1/34530.pdf
https://clok.uclan.ac.uk/34530/1/34530.pdf
Autor:
Zsuzsanna Varga, Thomas Ruhstaller, Ulrike Perriard, Dirk Klingbiel, Tilman T. Rau, Jean-Christophe Tille, Beat Thuerlimann, Hanne Hawle, Qiyu Li, Wolfram Jochum
Publikováno v:
Varga, Zsuzsanna; Li, Qiyu; Jochum, Wolfram; Perriard, Ulrike; Rau, Tilman; Tille, Jean-Christoph; Hawle, Hanne; Klingbiel, Dirk; Thuerlimann, Beat; Ruhstaller, Thomas (2019). Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort. Scientific reports, 9(1), p. 13534. Springer Nature 10.1038/s41598-019-49638-4
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol. 9, No 1 (2019) P. 13534
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol. 9, No 1 (2019) P. 13534
Scientific Reports
The assessment of Ki-67 in early-stage breast cancer has become an important diagnostic tool in planning adjuvant therapy, particularly for the administration of additional chemotherapy to hormone-responsive patients. An accurate determination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509ed0eb6c511bb431eb561f8c240921
Autor:
I.A.M. Mandjes, Esther H. Lips, Bas B. Koolen, Lennart Mulder, Sjoerd Rodenhuis, Jelle Wesseling, L. Wessels, J. J. de Ronde
Publikováno v:
Breast Cancer Research and Treatment
Breast cancer research and treatment, 140(1), 63-71. Springer New York
Breast cancer research and treatment, 140(1), 63-71. Springer New York
Intrinsic subtypes are widely accepted for the classification of breast cancer. Lacking gene expression data, surrogate classifications based on immunohistochemistry (IHC) have been proposed. A recent St. Gallen consensus meeting recommends to use th
Publikováno v:
Pathology Oncology Research
Breast invasive micropapillary carcinoma (IMPC) is a rare subtype of breast cancer with a high potential of lymph node metastasis, aggressive clinical behavior, and poor disease-free or overall survival. Expression of leucine zipper putative tumor su
Autor:
Wilma L. Lingle, Beiyun Chen, Michael F. Press, Howard M. Stern, Monica M. Reinholz, Mona Shing, Edith A. Perez, Robert B. Jenkins, Amylou C. Dueck, Soonmyung Paik, Reid G. Meyer, Melanie Finnigan, Marc Buyse, JoAnne Zujewski, Ivonne Villalobos, Dennis J. Slamon, Chungyeul Kim, Anne E. Wiktor
Publikováno v:
Breast Cancer Research and Treatment
A comprehensive, blinded, pathology evaluation of HER2 testing in HER2-positive/negative breast cancers was performed among three central laboratories. Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) analyses were performed o
Autor:
Feng Jin, Fan Yao, Yanan Sun, Ayao Guo, Chong Liu, Quanxiu Jin, Chuifeng Fan, Xiaoyun Mao, Bo Li, Shu Guan
Publikováno v:
Tumour Biology
CXCR4 and its ligand CXCL12 can promote the proliferation, survival, and invasion of cancer cells. They have been shown to play an important role in regulating metastasis of breast cancer to specific organs. High CXCR4 expression was also correlated
Autor:
Marc J. van de Vijver, Gerrit K. J. Hooijer, Hugo M. Horlings, Jelle Wesseling, Hans Halfwerk, C. Dilara Savci-Heijink
Publikováno v:
Breast Cancer Research and Treatment
Breast cancer research and treatment, 150(3), 547-557. Springer New York
Breast cancer research and treatment, 150(3), 547-557. Springer New York
Among breast cancer patients who develop distant metastases, there is marked variability in the clinical course, including metastasis pattern. Here, we present a retrospective study of breast cancer patients who all developed distant metastases focus
Autor:
Matthew J. Ellis, Cynthia X. Ma
Publikováno v:
Breast Cancer Research and Treatment
Neoadjuvant chemotherapy trials have consistently reported lower response rates in hormone receptor-positive (HR+) breast cancer when compared with HR− cases. Preoperative endocrine therapy has therefore become a logical alternative and has gained
Autor:
Anna Glajcar, Joanna Szpor, Katarzyna Ewa Tyrak, Joanna Streb, Agnieszka Pacek, Krzysztof Okoń, Florence Chan, Diana Hodorowicz-Zaniewska
Publikováno v:
Virchows Archiv
Mast cells (MCs) are a part of the innate immune system. The MC functions toward cancer are partially based on the release of chymase and tryptase. However, the MC effect on breast cancer is controversial. The aim of our study was to investigate the