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Autor:
Cecilia Gelfi, Luigi Minafra, Valentina Bravatà, Rossana Norata, Carmelo Lupo, Massimo Viola, Cristina Messa
Publikováno v:
BMC research notes 5 (2012): 343. doi:10.1186/1756-0500-5-343
info:cnr-pdr/source/autori:Luigi Minafra; Rossana Norata; Valentina Bravatà; Massimo Viola; Carmelo Lupo; Cecilia Gelfi; Cristina Messa./titolo:Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report./doi:10.1186%2F1756-0500-5-343/rivista:BMC research notes/anno:2012/pagina_da:343/pagina_a:/intervallo_pagine:343/volume:5
BMC Research Notes
BMC Research Notes, Vol 5, Iss 1, p 343 (2012)
info:cnr-pdr/source/autori:Luigi Minafra; Rossana Norata; Valentina Bravatà; Massimo Viola; Carmelo Lupo; Cecilia Gelfi; Cristina Messa./titolo:Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report./doi:10.1186%2F1756-0500-5-343/rivista:BMC research notes/anno:2012/pagina_da:343/pagina_a:/intervallo_pagine:343/volume:5
BMC Research Notes
BMC Research Notes, Vol 5, Iss 1, p 343 (2012)
Background Immortalized cancer cell lines are now well-established procedures in biomedicine for a more complete understanding of cellular processes in cancer. However, they are more useful in preparation of fresh tumour tissue, in order to obtain ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879cc7aa8288ebe6181e5c13b2617698
http://hdl.handle.net/10281/37353
http://hdl.handle.net/10281/37353
Publikováno v:
Cellular Oncology (Dordrecht)
Background Hypoxia Inducible Factor-1α (HIF-1α) expression in breast cancer is associated with a poor clinical outcome. HIF-1α shows two expression patterns: the canonical poor prognosis hypoxia-related perinecrotic pattern and a diffuse expressio
Autor:
Mårten Fernö, Pär-Ola Bendahl, Åke Borg, Lao H. Saal, Cecilia Hegardt, Dorthe Grabau, Gabriella Honeth, Kristina Lövgren, Markus Ringnér, Sofia K. Gruvberger-Saal
Publikováno v:
Breast Cancer Research. 10(3)
Human breast tumors are heterogeneous and consist of phenotypically diverse cells. Breast cancer cells with a CD44+/CD24- phenotype have been suggested to have tumor-initiating properties with stem cell-like and invasive features, although it is uncl
Autor:
Sarah Kirk, Tania Szado, Lukas C. Amler, Young-Hyuck Im, Jennifer Eng-Wong, Giampaolo Bianchini, Pinuccia Valagussa, Tadeusz Pienkowski, Luca Gianni, Giulia Bianchi, Lila Zabaglo, Mitch Dowsett, Astrid Kiermaier, Mei Ching Liu, Ling Ming Tseng
Publikováno v:
Breast Cancer Research : BCR
Background NeoSphere showed significantly higher pathologic complete response (pCR) with neoadjuvant pertuzumab, trastuzumab, and docetaxel compared with trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel. We assess
Autor:
Kátia Maciel Pincerato, Matt van de Rijn, Carlos E. Bacchi, Filomena Marino Carvalho, Livia M. Bacchi
Publikováno v:
BMC Women's Health
Background To compare the distribution of the intrinsic molecular subtypes of breast cancer based on immunohistochemical profile in the five major geographic regions of Brazil, a country of continental dimension, with a wide racial variation of peopl
Autor:
Anna Morabito, Beatrice Dozin, Barbara Banelli, Gianluigi Lunardi, Alessia D'Alonzo, Silvia Boero, Maria Pia Pistillo, Roberta Carosio, Alessia Levaggi, Sandra Salvi, Massimo Romani, Lucia Del Mastro, Francesca Poggio, Sonia Lastraioli, Alessandro Poggi, Patrizia Piccioli, Barbara Cardinali
Publikováno v:
Journal of Translational Medicine
Background Trastuzumab is a humanized monoclonal antibody (mAb) currently used for the treatment of breast cancer (BC) patients with HER-2 overexpressing tumor subtype. Previous data reported the involvement of FcγRIIIA/IIA gene polymorphisms and/or
Autor:
Annette M. Molinaro, Maria T Baquero, Karen Lostritto, David L. Rimm, Lyndsay Harris, Mark Gustavson, Franck Appia, Kimberly A Bassi, Robert L. Camp
Publikováno v:
Breast Cancer Research : BCR
Introduction Microtubule associated proteins (MAPs) endogenously regulate microtubule stabilization and have been reported as prognostic and predictive markers for taxane response. The microtubule stabilizer, MAP-tau, has shown conflicting results. W
Autor:
Emad A. Rakha, Keith R. Neal, Mohammed A. Aleskandarany, Fabrício F. T. Barros, Ian O. Ellis, Jorge S. Reis-Filho, Ahmed Benhasouna, Andrew R. Green
Publikováno v:
Breast Cancer Research : BCR
Introduction Although the prognostic significance of proliferation in early invasive breast cancer has been recognized for a long time, recent gene-expression profiling studies have reemphasized its biologic and prognostic value and the potential app
Autor:
Edgar Dahl, Amjad Naami, Matthias W. Beckmann, Erik Noetzel, Michael F. Press, Jürgen Veeck, Nuran Bektas, Arndt Hartmann, Ruth Knüchel, Glen Kristiansen, Arno Dimmler, Peter A. Fasching
Publikováno v:
Breast Cancer Research : BCR
Breast cancer research 10(4), R58-R58 (2008). doi:10.1186/bcr2117
Breast cancer research 10(4), R58-R58 (2008). doi:10.1186/bcr2117
Introduction ISG15 is an ubiquitin-like molecule that is strongly upregulated by type I interferons as a primary response to diverse microbial and cellular stress stimuli. However, alterations in the ISG15 signalling pathway have also been found in s
Publikováno v:
Breast Cancer Research : BCR
Introduction Classification of breast cancers according to the HER-2 oncogene status is of central importance in the selection of post-surgical therapies. A decrease in the proportion of HER-2-positive breast cancer has been suspected, but no data on