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pro vyhledávání: ''
Autor:
Marta Vilalta, Adam J. Krieg, Caiyun G. Li, Eui Jung Moon, Amato J. Giaccia, Jen-Tsan Chi, Edward E. Graves, Jacob G. Kirkland, Stephano S. Mello, Anh N. Diep, Marjan Rafat, Yu Miao, Edward L. LaGory, Laura D. Attardi, Kaushik N. Thakkar, Laura Castellini, Ik Jae Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Hypoxia plays a critical role in tumor progression including invasion and metastasis. To determine critical genes regulated by hypoxia that promote invasion and metastasis, we screen fifty hypoxia inducible genes for their effects on invasion. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574b64acea8911667a49665037069c39
https://doi.org/10.1038/s41467-021-24631-6
https://doi.org/10.1038/s41467-021-24631-6
Autor:
Nelofar Nargis, Gunjan Mandal, Samir Jana, Thomas A. Hughes, Soumya Chatterjee, Annesha Chatterjee, Laura M. Wastall, Himansu Roy, Arindam Bhattacharyya
Publikováno v:
British Journal of Cancer
BACKGROUND: Cancer-associated fibroblasts (CAFs) are known to impact on tumour behaviour, but the mechanisms controlling this are poorly understood. METHODS: Breast normal fibroblasts (NFs) or CAFs were isolated from cancers by laser microdissection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957384df57b4414e3eef66fa38c6c18b
https://eprints.whiterose.ac.uk/149993/8/s41416-019-0566-7.pdf
https://eprints.whiterose.ac.uk/149993/8/s41416-019-0566-7.pdf
Autor:
Elena Gómez-Marín, Sabrina Rivero, José A. Guerrero-Martínez, José C. Reyes, Jorge García-Martínez
Publikováno v:
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 2, Pp 1-12 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 2, Pp 1-12 (2019)
Digital.CSIC. Repositorio Institucional del CSIC
The epithelial-to-mesenchymal transition (EMT) and its reversion (MET) are related to tumor cell dissemination and migration, tumor circulating cell generation, cancer stem cells, chemoresistance, and metastasis formation. To identify chromatin and e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0cd2f27d3087907ada3b110e995e03
Autor:
Ana Luísa Correia, Ana Sofia Ribeiro, Fernando Schmitt, Marc Bracke, Bárbara Sousa, Raquel Seruca, Joana Paredes, André Albergaria
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cell-cell adhesion is an elementary process in normal epithelial cellular architecture. Several studies have shown the role mediated by cadherins in this process, besides their role in the maintenance of cell polarity, differentiation and cell growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678d05d177b8757189b519b779289408
https://hdl.handle.net/1822/67565
https://hdl.handle.net/1822/67565
Publikováno v:
Breast Cancer Research and Treatment
There is a growing belief that the metabolic program of breast tumor cells could be a therapeutic target. Yet, without detailed information on central carbon metabolism in breast tumors it is impossible to know which metabolic pathways to target, and
Autor:
Timothy P. Fleming, Sreeraj G. Pillai, Rebecca Aft, Mark A. Watson, Chidananda M. Siddappa, Kathryn Trinkaus, Nupur Dasgupta
Publikováno v:
Breast Cancer Research and Treatment
The presence of disseminated tumor cells (DTCs) in the bone marrow (BM) of breast cancer patients is prognostic for early relapse. In the present study, we analyzed the gene expression profiles from BM cells of breast cancer patients to identify mole
Autor:
Feng Jin, Fan Yao, Yanan Sun, Ayao Guo, Chong Liu, Quanxiu Jin, Chuifeng Fan, Xiaoyun Mao, Bo Li, Shu Guan
Publikováno v:
Tumour Biology
CXCR4 and its ligand CXCL12 can promote the proliferation, survival, and invasion of cancer cells. They have been shown to play an important role in regulating metastasis of breast cancer to specific organs. High CXCR4 expression was also correlated
Publikováno v:
Molecular Imaging and Biology; Vol 13
Molecular Imaging and Biology
Molecular Imaging and Biology
Purpose The aim of this study is to use multicolor intravital imaging together with an inducible cell model to compare metastatic behavior of control and genetically modified breast cancer cell populations within the intact primary tumor of a mouse.
Autor:
Zhaomei Mu, Massimo Cristofanilli, Sandra V. Fernandez, Zaiming Ye, Khoi Chu, Lucy Aburto-Chumpitaz, Jianming Pei, Kimberly M. Boley, Andres J. Klein-Szanto, R. K. Alpaugh, Yu Cao, Sankar Addya, Fredika M. Robertson, Yong Huang, Karthik Devarajan, Kathy Q. Cai
Publikováno v:
Breast Cancer Research and Treatment
Inflammatory breast cancer (IBC) is the most aggressive type of advanced breast cancer characterized by rapid proliferation, early metastatic development and poor prognosis. Since there are few preclinical models of IBC, there is a general lack of un
Publikováno v:
BMC Cancer
BMC CANCER(13)
BMC CANCER(13)
Background Heregulin (HRG; also known as neuregulin) is a ligand for ErbB3. One of its isotypes, HRG-β1, binds to ErbB3 and forms heterodimers with other ErbB family members, thereby enhancing the proliferation and tumorigenesis of breast cancer cel