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Autor:
Graham Ball, Jonathon Blake, Amanda Devaney, Aoife Lowery, Christophe Lemetre, Vladimir Benes, Sabine Schmidt, Roisin E McNeill, Nicola Miller, Pamela A Davoren, Michael J. Kerin
Publikováno v:
Breast Cancer Research : BCR
peer-reviewed Introduction Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the oestrogen, progesterone and HER2/ neu receptors which characterize clinically distinct breast tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2ae9d83199bb46e19c5d330eaa7d0f
http://hdl.handle.net/10379/12508
http://hdl.handle.net/10379/12508
Publikováno v:
Cellular Oncology (Dordrecht)
Background Hypoxia Inducible Factor-1α (HIF-1α) expression in breast cancer is associated with a poor clinical outcome. HIF-1α shows two expression patterns: the canonical poor prognosis hypoxia-related perinecrotic pattern and a diffuse expressio
Autor:
Paul J. van Diest, Marise R. Heerma van Voss, Elsken van der Wall, Joost Bart, Petra van der Groep
Publikováno v:
Cellular Oncology (Dordrecht)
Scopus-Elsevier
Cellular oncology, 34(1), 3-10. SPRINGER
Scopus-Elsevier
Cellular oncology, 34(1), 3-10. SPRINGER
Introduction The BRCA1 protein makes mammary stem cells differentiate into mature luminal and myoepithelial cells. If a BRCA1 mutation results in a differentiation block, an enlarged stem cell component might be present in the benign tissue of BRCA1
Autor:
Cathy B. Moelans, Patrick W. B. Derksen, Horst Buerger, Gábor Cserni, Eva J. Vlug, Peter Bult, Paul J. van Diest, Cigdem Ercan
Publikováno v:
Analytical Cellular Pathology-Cellular Oncology, 38, 397-405
Cellular Oncology (Dordrecht)
Cellular oncology, 38(5), 397. Springer Netherlands
Analytical Cellular Pathology-Cellular Oncology, 38, 5, pp. 397-405
Cellular Oncology (Dordrecht)
Cellular oncology, 38(5), 397. Springer Netherlands
Analytical Cellular Pathology-Cellular Oncology, 38, 5, pp. 397-405
Contains fulltext : 152476.pdf (Publisher’s version ) (Open Access) BACKGROUND: Pleomorphic invasive lobular cancer (pleomorphic ILC) is a rare variant of ILC that is characterized by a classic ILC-like growth pattern combined with an infiltrative
Autor:
Emmanuelle Menet, Frédéric Dollé, Stéphanie Guillermet, Keyvan Rezai, Bertrand Kuhnast, Karine Siquier, Benoit Jego, Bertrand Tavitian, Raphaël Boisgard, Jean-Louis Alberini, Renaud Maroy, Saik Urien, Benoit Thézé
Publikováno v:
Molecular Imaging and Biology
Molecular Imaging and Biology, Springer Verlag, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Molecular Imaging and Biology, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Molecular Imaging and Biology, Springer Verlag, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Molecular Imaging and Biology, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Purpose Transgenic mice expressing the polyoma middle T oncoprotein (PyMT) in the mammary epithelium were explored by multimodal imaging to monitor longitudinally spontaneous tumor growth and response to chemotherapy. Procedures Positron emission tom
Autor:
Ntziachristos Vasilis, Henriette J. G. Arts, Lucia M. A. Crane, Rick G. Pleijhuis, Niels J. Harlaar, George Themelis, Athanasios Sarantopoulos, Ate G.J. van der Zee, Gooitzen M. van Dam
Publikováno v:
Molecular Imaging and Biology, 13(5), 1043-1049. SPRINGER
Molecular Imaging and Biology
Molecular Imaging and Biology
Purpose Real-time intraoperative near-infrared fluorescence (NIRF) imaging is a promising technique for lymphatic mapping and sentinel lymph node (SLN) detection. The purpose of this technical feasibility pilot study was to evaluate the applicability
Publikováno v:
Molecular Imaging and Biology; Vol 13
Molecular Imaging and Biology
Molecular Imaging and Biology
Purpose The aim of this study is to use multicolor intravital imaging together with an inducible cell model to compare metastatic behavior of control and genetically modified breast cancer cell populations within the intact primary tumor of a mouse.
Publikováno v:
Molecular Imaging and Biology
This study aims to evaluate the effect of dimercaptosuccinic acid (DMSA)-coated superparamagnetic iron oxide (γ-Fe(2)O(3)@DMSA) bearing the 2-deoxy-D-glucose (2-DG) ligand on targeting tumors with high-glucose metabolism.γ-Fe(2)O(3)@DMSA and 2-DG-c
Autor:
Gwyn T. Williams, Carlos Caldas, Mirna Mourtada-Maarabouni, Andrew R. Green, Mark R. Pickard, Ian O. Ellis, Vanessa L. Hedge
Publikováno v:
Breast Cancer Research : BCR
INTRODUCTION: Programmed cell death through apoptosis plays an essential role in the hormone-regulated physiological turnover of mammary tissue. Failure of this active gene-dependent process is central both to the development of breast cancer and to
Autor:
Janet R. Daling, Danielle M. Friedrichsen, Elaine A. Ostrander, Kathleen E. Malone, David R. Doody
Publikováno v:
Breast Cancer Research
Introduction The cell-cycle checkpoint kinase (CHEK)2 protein truncating mutation 1100delC has been associated with increased risk for breast or prostate cancer. Multiple studies have found an elevated frequency of the 1100delC variant in specific st