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Autor:
Chris Twelves, Matthew Guo, Larisa Reyderman, Ishtiaq Husain Zubairi, R. Morrison, Nicola Cresti, Claudio Savulsky, Alan Anthoney, Vladimir Semiglazov, Ruth Plummer, T.R. Jeffry Evans, Constanta Timcheva
Publikováno v:
British Journal of Cancer
Background: \ud Capecitabine and eribulin are widely used as single agents in metastatic breast cancer (MBC) and have nonoverlapping toxicities.\ud \ud Methods: \ud In phase 1b (dose escalation), patients with advanced, treatment-refractory, solid tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bccd2276eddef510b3a7b2fcc67aa0
https://eprints.whiterose.ac.uk/148290/1/s41416-018-0366-5.pdf
https://eprints.whiterose.ac.uk/148290/1/s41416-018-0366-5.pdf
Autor:
Hanne Frydenberg, Gro F. Bertheussen, Vidar Gordon Flote, Hartmut Schäfer, Inger Thune, Steinar Lundgren, Ellen Schlichting, Torfinn Støve Madssen, Erik Wist, Tone Frost Bathen, Riyas Vettukattil, Guro F. Giskeødegård, Jon Lømo, Hans E. Fjøsne
Publikováno v:
British Journal of Cancer
Background Breast cancer treatment has metabolic side effects, potentially affecting risk of cardiovascular disease (CVD) and recurrence. We aimed to compare alterations in serum metabolites and lipoproteins during treatment between recipients and no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160be7e8db63fd6c4a60bb91080f4b51
https://hdl.handle.net/11250/2592790
https://hdl.handle.net/11250/2592790
Autor:
Sean G. Rudd, Shruti Regmi, Roni H. G. Wright, Evert Homan, Olga Loseva, Thomas Helleday, Sabin Llona-Minguez, Olov A. Wallner, Ingrid Almlöf, Anna-Lena Gustavsson, Jofre Font-Mateu, Rebecka Isaksson, Megan Carter, Ann-Sofie Jemth, Pål Stenmark, Thomas Lundbäck, Helena Almqvist, Pawel Baranczewski, Kia Strömberg, Nicholas C.K. Valerie, Brent D. G. Page, Martin Scobie, Fredrik Jeppsson, Hanna Axelsson, Miguel Beato
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been implicated in ADP-ribose and 8-oxo-guanine metabolism and was recently identified as a rheosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248a82c4c016f63cf19a08615089b281
http://hdl.handle.net/20.500.12328/3012
http://hdl.handle.net/20.500.12328/3012
Autor:
C. Rose, R Leonard, M Tubiana-Hulin, Denis Lacombe, J Vinholes, J Wildiers, J Michel, Robert E. Coleman, J Nortier, J. Ford, F. Mignolet, P Bastit
Publikováno v:
British Journal of Cancer
This study was designed to evaluate new bone resorption and tumour markers as possible alternatives to serial plain radiographs for the assessment of response to treatment. Thirty-seven patients with newly diagnosed bone metastases from breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f16dd46c0774b038d4bedfedc3bf7f
Autor:
Andrzej Sygut, Julia Kruk-Jeromin, Ireneusz Majsterek, Adam Dziki, Grażyna Pasz-Walczak, Jan Rykała, Karolina Przybyłowska
Publikováno v:
Pathology Oncology Research
Tumoural angiogenesis is essential for the growth and spread of breast cancer cells. Therefore the aim of this study was to assess the diagnostic performance of angiogenesis markers in tumours and there reflecting levels in serum of breast cancer pat
Autor:
Rossana Bossi, Jørn Olsen, Manhai Long, Eva Cecilie Bonefeld-Jørgensen, Stine Overvad Fredslund
Publikováno v:
Cancer Causes & Control
Bonefeld-Jørgensen, E C, Long, M, Fredslund, S O, Bossi, R & Olsen, J 2014, ' Breast cancer risk after exposure to perfluorinated compounds in Danish women : a case-control study nested in the Danish National Birth Cohort ', Cancer causes & control : CCC, vol. 25, no. 11, pp. 1439-1448 . https://doi.org/10.1007/s10552-014-0446-7
Bonefeld-Jørgensen, E C, Long, M, Fredslund, S O, Bossi, R & Olsen, J 2014, ' Breast cancer risk after exposure to perfluorinated compounds in Danish women : a case-control study nested in the Danish National Birth Cohort ', Cancer causes & control : CCC, vol. 25, no. 11, pp. 1439-1448 . https://doi.org/10.1007/s10552-014-0446-7
Objective Animal studies have indicated that perfluoroalkylated substances (PFAS) increase mammary fibroadenomas. A recent case–control study in Greenlandic Inuit women showed an association between the PFAS serum levels and breast cancer (BC) risk
Publikováno v:
Breast Cancer Research and Treatment
Discrete windows of susceptibility to toxicants have been identified for the breast, including in utero, puberty, pregnancy, and postpartum. We tested the hypothesis that polychlorinated biphenyls (PCBs) measured during the early postpartum predict i
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background The human Y-box-binding protein 1 (YB-1) is a member of the DNA/RNA-binding family of proteins that regulates transcription and translation of genes. Previous studies suggest that YB-1 may have an oncogenic role in various cancers. In this
Autor:
Antonio C. Wolff, Allison M. Deal, Amal Melhem-Bertrandt, Nan Lin, Lisa A. Carey, Olga Karginova, Carey K. Anders, J. Keith Smith, Charles M. Perou, Eric P. Winer, John T. Carpenter, Vandana G. Abramson, P. Kelly Marcom, Rita Nanda, Joel S. Parker, Vered Stearns, Amy H. Peterman, Aleix Prat, Anna Maria Storniolo, Michelle E. Melisko, Catherine Van Poznak, Minetta C. Liu, Shannon Puhalla, Jonathan S. Berg
Publikováno v:
Breast Cancer Research and Treatment
Nearly half of patients with advanced triple negative breast cancer (TNBC) develop brain metastases (BM) and most will also have uncontrolled extracranial disease. This study evaluated the safety and efficacy of iniparib, a small molecule anti-cancer
Publikováno v:
Tumour Biology
The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of vitamin D. A great number of studies regarding the association between BsmI polymorphism in the VDR gene and breast cancer have been published. However, the results have b