Zobrazeno 1 - 10
of 96
pro vyhledávání: ''
Autor:
Mira, A.1, Isella, C.1, Renzulli, T.1, Cantarella, D.1, Martelli, M. L.1, Medico, E.1 enzo.medico@ircc.it
Publikováno v:
Oncogene. 12/17/2009, Vol. 28 Issue 50, p4444-4455. 12p. 1 Chart, 7 Graphs.
Autor:
Waleed S. Al Amri, William E. Hughes, James L. Thorne, Geoff Wells, Ian M. Carr, Brian V Hogan, Thomas A. Hughes, Fiona Langlands, Arindam Pramanik, Layla K. Younis, Stacey J. Jones, Sarah A. Harris, Eldo T. Verghese, Rebecca Millican-Slater, Nevine M.F. El Deeb, Mervat A. Hamza, Baek Kim, Noha Gwili
Publikováno v:
British Journal of Cancer
Background Breast cancer stem cells (BCSCs) are drivers of therapy-resistance, therefore are responsible for poor survival. Molecular signatures of BCSCs from primary cancers remain undefined. Here, we identify the consistent transcriptome of primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a64defdd7881cec05092b3963a5ac9
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
Autor:
James L. Thorne, Melina C. Teske, Robyn V. Broad, Andrew M. Hanby, Laura M. Wastall, Stacey J. Jones, Thomas A. Hughes
Publikováno v:
British Journal of Cancer
Background Triple negative breast cancers (TNBC) have poor prognoses despite aggressive treatment with cytotoxic chemotherapy. Cancer-associated fibroblasts (CAFs) are prominent in tumour stroma. Our hypothesis was that CAFs modulate chemotherapy sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027115557c95f3f47f1ecb119dec9f3d
Autor:
Elise Klæstad, Signe Opdahl, Monica J. Engstrøm, Elisabeth Wik, Borgny Ytterhus, Anna M. Bofin, Marit Valla
Publikováno v:
Breast Cancer Research and Treatment
Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy number change and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49102c4df90ac263d4c308ee2094e138
https://hdl.handle.net/11250/2672584
https://hdl.handle.net/11250/2672584
Autor:
Nelofar Nargis, Gunjan Mandal, Samir Jana, Thomas A. Hughes, Soumya Chatterjee, Annesha Chatterjee, Laura M. Wastall, Himansu Roy, Arindam Bhattacharyya
Publikováno v:
British Journal of Cancer
BACKGROUND: Cancer-associated fibroblasts (CAFs) are known to impact on tumour behaviour, but the mechanisms controlling this are poorly understood. METHODS: Breast normal fibroblasts (NFs) or CAFs were isolated from cancers by laser microdissection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957384df57b4414e3eef66fa38c6c18b
https://eprints.whiterose.ac.uk/149993/8/s41416-019-0566-7.pdf
https://eprints.whiterose.ac.uk/149993/8/s41416-019-0566-7.pdf
Autor:
Mel Fox, Gary C. Starling, Mian Su, Sonia Tanlimco, Debra Chao, Shiming Ye, Donghee Choi, Johnny Yin, Lisa Durkin, Patricia Culp, Yongke Zhang, Eric D. Hsi, Mien Sho, Han Kim
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background The receptor for the cytokine TWEAK (TweakR) is a cell surface member of the tumor necrosis factor receptor superfamily with diverse biological roles. TNFRSF family members are appealing therapeutic targets in oncology due to their aberran
Autor:
Gunnar Mellgren, Sara Gandini, Andrea Decensi, Jennifer Gjerde, Aliana Guerrieri-Gonzaga, Line L. Haugan Moi, Ernst A. Lien, Valentina Aristarco
Publikováno v:
Breast Cancer Research and Treatment
Tamoxifen dosage is based on the one-dose-fits-all approach. The anticancer effect of tamoxifen is believed to be due to the metabolites, 4-hydroxytamoxifen (4OHtam), and 4-hydroxy-N-desmethyltamoxifen (4OHNDtam/endoxifen). These demethylated metabol
Autor:
Marie K. Kirby, Jason Gertz, Amy S. Nesmith, William E. Grizzle, Nicholas S. Davis, Patsy G. Oliver, Kevin M. Bowling, Katherine E. Varley, Albert F. LoBuglio, Richard M. Myers, Brian S. Roberts, Andres Forero, Donald J. Buchsbaum
Publikováno v:
Breast Cancer Research and Treatment
Read-through fusion transcripts that result from the splicing of two adjacent genes in the same coding orientation are a recently discovered type of chimeric RNA. We sought to determine if read-through fusion transcripts exist in breast cancer. We pe
Autor:
Emmanuelle Menet, Frédéric Dollé, Stéphanie Guillermet, Keyvan Rezai, Bertrand Kuhnast, Karine Siquier, Benoit Jego, Bertrand Tavitian, Raphaël Boisgard, Jean-Louis Alberini, Renaud Maroy, Saik Urien, Benoit Thézé
Publikováno v:
Molecular Imaging and Biology
Molecular Imaging and Biology, Springer Verlag, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Molecular Imaging and Biology, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Molecular Imaging and Biology, Springer Verlag, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Molecular Imaging and Biology, 2016, 18 (4), pp.617-626. ⟨10.1007/s11307-015-0916-7⟩
Purpose Transgenic mice expressing the polyoma middle T oncoprotein (PyMT) in the mammary epithelium were explored by multimodal imaging to monitor longitudinally spontaneous tumor growth and response to chemotherapy. Procedures Positron emission tom
Autor:
Melissa A. Troester, Olga Karginova, Erick Roman, Charles M. Perou, Aleix Prat, Xiaping He, Cheng Fan, Barbara Adamo, J. Chuck Harrell, Joel S. Parker, Lisa M. Bixby
Publikováno v:
Breast Cancer Research and Treatment
Five molecular subtypes (luminal A, luminal B, HER2-enriched, basal-like, and claudin-low) with clinical implications exist in breast cancer. Here, we evaluated the molecular and phenotypic relationships of (1) a large in vitro panel of human breast