Zobrazeno 1 - 10
of 198
pro vyhledávání: ''
Autor:
Amadou, A., Freisling, H., Jenab, M., Tsilidis, K.K., Trichopoulou, A., Boffetta, P., Van Guelpen, B., Mokoroa, O., Wilsgaard, T., Kee, F., Schöttker, B., Ordóñez-Mena, J.M., Männistö, S., Söderberg, S., Vermeulen, R.C.H., Quirós, J.R., Liao, L.M., Sinha, R., Kuulasmaa, K., Brenner, H., Romieu, I., IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Sub Algemeen Theoretical Physics
Publikováno v:
British Journal of Cancer, 124(11), 1882. Nature Publishing Group
Br J Cancer
Br J Cancer
BACKGROUND: We investigated whether associations between prevalent diabetes and cancer risk are pertinent to older adults and whether associations differ across subgroups of age, body weight status or levels of physical activity. METHODS: We harmonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6d0f1003ec6d68dd57d4e02b0c362e
https://ora.ox.ac.uk/objects/uuid:85426259-76ba-4a69-b8d2-4c310484052f
https://ora.ox.ac.uk/objects/uuid:85426259-76ba-4a69-b8d2-4c310484052f
Autor:
Ring, A., Battisti, N.M.L., Reed, M.W.R., Herbert, E., Morgan, J.L., Bradburn, M., Walters, S.J., Collins, K.A., Ward, S.E., Holmes, G.R., Burton, Maria, Lifford, K., Edwards, A., Robinson, T.G., Martin, C., Chater, T., Pemberton, K.J., Brennan, A., Cheung, K.L., Todd, A., Audisio, R.A., Wright, J., Simcock, R., Green, T., Revell, D., Gath, J., Horgan, K., Holcombe, C., Winter, M.C., Naik, J., Parmeshwar, R., Gosney, M.A., Hatton, M.Q., Thompson, A.M., Wyld, L., Collins, K., Ward, S., Holmes, G., Morgan, J., Walters, S., Burton, M., Brain, K., Robinson, T., Pemberton, K., Shrestha, A., Nettleship, A., Richards, P., Harder, H., Audisio, R., Murray, C., Thomson, A.M., Gosney, M., Hatton, M., Armitage, F., Patnick, J., Revill, D., Winter, M.
Publikováno v:
British Journal of Cancer
Background Chemotherapy improves outcomes for high risk early breast cancer (EBC) patients but is infrequently offered to older individuals. This study determined if there are fit older patients with high-risk disease who may benefit from chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed056944ecd27827ab3bd963813fe40
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
Autor:
Beverley S. Speight, Marc Tischkowitz
Publikováno v:
Journal of Genetic Counseling
Germline mutations in BRCA1/BRCA2 significantly increase the risk of breast and ovarian cancer in women. This case report describes a BRCA1 germline mutation identified in a woman with stage IV epithelial ovarian cancer and the provision of genetic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b90b871eb5876d60696048fbb8078c6
https://www.repository.cam.ac.uk/handle/1810/267347
https://www.repository.cam.ac.uk/handle/1810/267347
Autor:
Frank Kee, Antonia Trichopoulou, José María Huerta, Heinz Freisling, Christina Bamia, Mazda Jenab, Paolo Boffetta, Anne Tjønneland, Ellen Kampman, Isabelle Romieu, Hendrik B. Bueno-de-Mesquita, Melina Arnold, Vassiliki Benetou, Hermann Brenner, Mark G. O'Doherty, Konstantinos K. Tsilidis, Tom Wilsgaard, Isabelle Soerjomataram, José M Ordóñez-Mena, Michael F. Leitzmann
Publikováno v:
British Journal of Cancer, 116, 11, pp. 1486-1497
British Journal of Cancer 116 (2017) 11
Freisling, H, Arnold, M, Soerjomataram, I, O'Doherty, M G, Ordóñez-Mena, J M, Bamia, C, Kampman, E, Leitzmann, M, Romieu, I, Kee, F, Tsilidis, K K, Tjønneland, A, Trichopoulou, A, Boffetta, P, Benetou, V, Bueno-de-Mesquita, H B A, Huerta, J M, Brenner, H, Wilsgaard, T & Jenab, M 2017, ' Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe ', British Journal of Cancer . https://doi.org/10.1038/bjc.2017.106
British Journal of Cancer, 116(11), 1486-1497
British Journal of Cancer, 116, 1486-1497
British Journal of Cancer
British Journal of Cancer 116 (2017) 11
Freisling, H, Arnold, M, Soerjomataram, I, O'Doherty, M G, Ordóñez-Mena, J M, Bamia, C, Kampman, E, Leitzmann, M, Romieu, I, Kee, F, Tsilidis, K K, Tjønneland, A, Trichopoulou, A, Boffetta, P, Benetou, V, Bueno-de-Mesquita, H B A, Huerta, J M, Brenner, H, Wilsgaard, T & Jenab, M 2017, ' Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe ', British Journal of Cancer . https://doi.org/10.1038/bjc.2017.106
British Journal of Cancer, 116(11), 1486-1497
British Journal of Cancer, 116, 1486-1497
British Journal of Cancer
BACKGROUND: We evaluated the associations of anthropometric indicators of general obesity (body mass index, BMI), an established risk factor of various cancer, and body fat distribution (waist circumference, WC; hip circumference, HC; and waist-to-hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09418e44d11a7f89e07058f346ca9f8a
http://hdl.handle.net/10044/1/49276
http://hdl.handle.net/10044/1/49276
Autor:
Liisa M. Pelttari, Paula Poikonen-Saksela, Kristiina Aittomäki, Päivi Auvinen, Arja Jukkola-Vuorinen, Sanna Hallamies, Heli Nevanlinna, Johanna Mattson, Carl Blomqvist, Antti Jekunen
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-5 (2017)
BMC Cancer
BMC Cancer
Background Several susceptibility genes have been established for female breast cancer, of which mutations in BRCA1 and especially in BRCA2 are also known risk factors for male breast cancer (MBC). The role of other breast cancer genes in MBC is less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4819e7805611ab5361165ecad3b1625
https://erepo.uef.fi/handle/123456789/5171
https://erepo.uef.fi/handle/123456789/5171
Autor:
Rebecca Troisi, Anne Gulbech Ording, Steinar Tretli, Anders Engeland, Henrik Toft Sørensen, Mika Gissler, Anders Ekbom, Tone Bjørge, Maarit K. Leinonen, Ingrid Glimelius, Tom Grotmol
Publikováno v:
Bjørge, T, Gissler, M, Ording, A G, Engeland, A, Glimelius, I, Leinonen, M, Sørensen, H T, Tretli, S, Ekbom, A, Troisi, R & Grotmol, T 2016, ' Reproductive history and risk of colorectal adenocarcinoma in parous women : a Nordic population-based case-control study ', B J C . https://doi.org/10.1038/bjc.2016.315
British Journal of Cancer
British Journal of Cancer
BACKGROUND: Data are conflicting regarding the role of endogenous sex hormones in colorectal carcinogenesis. In this large population-based study, we pooled data from birth and cancer registries in four Nordic countries, to evaluate the risk of color
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beb9ea8202f33e87fd121fd3dfadbc3
https://hdl.handle.net/1956/13056
https://hdl.handle.net/1956/13056
Autor:
Oumar Camara, Carola Rabenstein, Cornelia Jörke, Klaus Hoeffken, Ingo B. Runnebaum, Katharina Pachmann, Anne Egbe, U. Hammer
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 135(4):643-647
In breast cancers, the gene for the growth factor receptor HER2 can be amplified leading to increased aggressiveness and metastasis formation. The monoclonal antibody trastuzumab prolongs relapse-free survival highly significantly but eventually many
Autor:
Jan Steffen, Michalina Dabrowska, Aneta Balabas, Magdalena Piatkowska, Dorota Nowakowska, Izabela Brozek, Anna Niwińska, Magdalena Ratajska, Jadwiga Rachtan, Janusz Limon, Anna Kluska
Publikováno v:
Familial Cancer
It is estimated that about 5–10% of ovarian and 2–5% of all breast cancer patients are carriers of a germline BRCA1 or BRCA2 gene mutation. Most families with detected BRCA1 or BRCA2 gene mutation are qualified for molecular testing on the basis
Publikováno v:
Cancer Microenvironment
Estrogen and various growth factors affecting tumor behavior are present in the breast cancer microenvironment, but their comprehensive effects and signal crosstalks are different in each case. However, there is no system to evaluate the factors, det
Autor:
Agnes Jager, Nyrée Smallenbroek, Caroline M. Seynaeve, Jan C. Drooger, Cynthia Epskamp, Bernadette A M Heemskerk-Gerritsen
Publikováno v:
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 156(3), 557-566. Springer New York
Breast Cancer Research and Treatment, 156(3), 557-566. Springer New York
Treatment with (neo)adjuvant chemotherapy for breast cancer, as currently given, causes cell damage by induction of double-strand DNA breaks. Because BRCA1 and BRCA2 proteins play a role in the repair of DNA damage, the efficacy of (neo)adjuvant chem