Zobrazeno 1 - 10
of 810
pro vyhledávání: ''
Autor:
Denis Le Bihan, Hiroyoshi Isoda, Masako Kataoka, Mami Iima, Yuji Nakamoto, Hirohiko Imai, Akihiko Yoshizawa, Yuko Someya
Publikováno v:
Scientific Reports. 12
We investigated the associations of time-dependent DWI, non-Gaussian DWI, and CEST parameters with histological biomarkers in a breast cancer xenograft model. 22 xenograft mice (7 MCF-7 and 15 MDA-MB-231) were scanned at 4 diffusion times [Td = 2.5/5
Autor:
Amadou, A., Freisling, H., Jenab, M., Tsilidis, K.K., Trichopoulou, A., Boffetta, P., Van Guelpen, B., Mokoroa, O., Wilsgaard, T., Kee, F., Schöttker, B., Ordóñez-Mena, J.M., Männistö, S., Söderberg, S., Vermeulen, R.C.H., Quirós, J.R., Liao, L.M., Sinha, R., Kuulasmaa, K., Brenner, H., Romieu, I., IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Sub Algemeen Theoretical Physics
Publikováno v:
British Journal of Cancer, 124(11), 1882. Nature Publishing Group
Br J Cancer
Br J Cancer
BACKGROUND: We investigated whether associations between prevalent diabetes and cancer risk are pertinent to older adults and whether associations differ across subgroups of age, body weight status or levels of physical activity. METHODS: We harmonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6d0f1003ec6d68dd57d4e02b0c362e
https://ora.ox.ac.uk/objects/uuid:85426259-76ba-4a69-b8d2-4c310484052f
https://ora.ox.ac.uk/objects/uuid:85426259-76ba-4a69-b8d2-4c310484052f
Autor:
Ring, A., Battisti, N.M.L., Reed, M.W.R., Herbert, E., Morgan, J.L., Bradburn, M., Walters, S.J., Collins, K.A., Ward, S.E., Holmes, G.R., Burton, Maria, Lifford, K., Edwards, A., Robinson, T.G., Martin, C., Chater, T., Pemberton, K.J., Brennan, A., Cheung, K.L., Todd, A., Audisio, R.A., Wright, J., Simcock, R., Green, T., Revell, D., Gath, J., Horgan, K., Holcombe, C., Winter, M.C., Naik, J., Parmeshwar, R., Gosney, M.A., Hatton, M.Q., Thompson, A.M., Wyld, L., Collins, K., Ward, S., Holmes, G., Morgan, J., Walters, S., Burton, M., Brain, K., Robinson, T., Pemberton, K., Shrestha, A., Nettleship, A., Richards, P., Harder, H., Audisio, R., Murray, C., Thomson, A.M., Gosney, M., Hatton, M., Armitage, F., Patnick, J., Revill, D., Winter, M.
Publikováno v:
British Journal of Cancer
Background Chemotherapy improves outcomes for high risk early breast cancer (EBC) patients but is infrequently offered to older individuals. This study determined if there are fit older patients with high-risk disease who may benefit from chemotherap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed056944ecd27827ab3bd963813fe40
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
http://sro.sussex.ac.uk/id/eprint/101218/1/s41416-021-01388-9.pdf
Publikováno v:
British Journal of Cancer
Background Some endogenous hormones have been associated with breast cancer risk, but the nature of these relationships is not fully understood. Methods UK Biobank was used. Hormone concentrations were measured in serum collected in 2006–2010, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d482614b3e60f0e3b3fcf0d952cf3d1b
https://ora.ox.ac.uk/objects/uuid:2298adb9-eb05-46ad-ae36-48abd7ac39d1
https://ora.ox.ac.uk/objects/uuid:2298adb9-eb05-46ad-ae36-48abd7ac39d1
Autor:
Masako Kataoka, Masakazu Toi, Kaori Togashi, Mami Iima, Akane Ohashi, Shotaro Kanao, Daniel Förnvik
Publikováno v:
European Radiology
To compare breast density measured on digital breast tomosynthesis (DBT) (BI-RADS-based breast composition and fully-automatic estimation) and magnetic resonance imaging (MRI) (BI-RADS amount of fibroglandular tissue), and to evaluate the diagnostic
Autor:
Lauren Lissner, Marisa O.D. Silva, Charlotta Rylander, Maarit A. Laaksonen, Elisabete Weiderpass
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Scientific Reports
Scientific Reports
There is a lack of tangible measures for directed public health action to halt the increase in weight and cancer. We estimated the fraction and preventable cases of all and major body fatness-related cancers attributable to 7-years weight gain (≥ 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eceb346315a3d49626abdc74a66840c5
https://hdl.handle.net/10037/23797
https://hdl.handle.net/10037/23797
Publikováno v:
Breast Cancer Research and Treatment
Purpose This systematic review examined educational training interventions for healthcare professionals (HCPs) discussing genetic testing and risk for hereditary breast cancer. There was a particular focus on the presence, and content, of communicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95c00137135ccdad16368a0165e339f
http://sro.sussex.ac.uk/id/eprint/92115/1/Starkings_et_al-2020-Breast_Cancer_Research_and_Treatment.pdf
http://sro.sussex.ac.uk/id/eprint/92115/1/Starkings_et_al-2020-Breast_Cancer_Research_and_Treatment.pdf
Autor:
Sylwia Kopijasz, Corran Roberts, Victoria Y Strauss, Shibani Nicum, Andrew R Clamp, Marcia Hall, Richard D. Kennedy, Ana Montes, Charlie Gourley, Jacinta Abraham, Michael R.L. Stratford, Susana Banerjee, Lisa K. Folkes
Publikováno v:
Roberts, C, Strauss, V Y, Kopijasz, S, Gourley, C, Hall, M, Montes, A, Abraham, J, Clamp, A, Kennedy, R, Banerjee, S, Folkes, L K, Stratford, M & Nicum, S 2020, ' Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours ', British Journal of Cancer, vol. 122, no. 4, pp. 483-490 . https://doi.org/10.1038/s41416-019-0674-4, https://doi.org/10.1038/s41416-019-0674-4
Roberts, C, Strauss, V Y, Kopijasz, S, Gourley, C, Hall, M, Montes, A, Abraham, J, Clamp, A, Kennedy, R, Banerjee, S, Folkes, L K, Stratford, M & Nicum, S 2020, ' Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours ', British Journal of Cancer, vol. 122, no. 4, pp. 483-490 . https://doi.org/10.1038/s41416-019-0674-4
British Journal of Cancer
Roberts, C, Strauss, V Y, Kopijasz, S, Gourley, C, Hall, M, Montes, A, Abraham, J, Clamp, A, Kennedy, R, Banerjee, S, Folkes, L K, Stratford, M & Nicum, S 2020, ' Results of a phase II clinical trial of 6-mercaptopurine (6MP) and methotrexate in patients with BRCA-defective tumours ', British Journal of Cancer, vol. 122, no. 4, pp. 483-490 . https://doi.org/10.1038/s41416-019-0674-4
British Journal of Cancer
BackgroundTumour cells with BRCA1/2 gene mutations demonstrate increased sensitivity to platinum and poly (ADP-ribose) polymerase (PARP) inhibitors. 6-mercaptopurine (6MP) was found to selectively kill BRCA-defective cells in a xenograft model as eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b494bdec4a88dbce8776a6e9b65b9c
https://doi.org/10.1038/s41416-019-0674-4
https://doi.org/10.1038/s41416-019-0674-4
Publikováno v:
British Journal of Cancer
Background Previous studies suggest a protective role of physical activity in breast cancer risk, largely based on self-reported activity. We aimed to clarify this association by examining breast cancer risk in relation to self-reported physical acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a722803fcba970203601d360bcec4002
https://ora.ox.ac.uk/objects/uuid:1e16a41e-f248-4e0f-8e5c-c35bdc9bd92c
https://ora.ox.ac.uk/objects/uuid:1e16a41e-f248-4e0f-8e5c-c35bdc9bd92c
Autor:
Lusine Tumyan, Daniel Schmolze, Joanne E. Mortimer, Daniel Abler, David A. Hormuth, Angela M. Jarrett, Vikram Adhikarla, Prativa Sahoo, Thomas E. Yankeelov, Russell C. Rockne
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Jarrett, Angela M.; Hormuth, David A.; Adhikarla, Vikram; Sahoo, Prativa; Abler, Daniel; Tumyan, Lusine; Schmolze, Daniel; Mortimer, Joanne; Rockne, Russell C.; Yankeelov, Thomas E. (2020). Towards integration of 64Cu-DOTA-trastuzumab PET-CT and MRI with mathematical modeling to predict response to neoadjuvant therapy in HER2 + breast cancer. Scientific reports, 10(1), p. 20518. Springer Nature 10.1038/s41598-020-77397-0
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Jarrett, Angela M.; Hormuth, David A.; Adhikarla, Vikram; Sahoo, Prativa; Abler, Daniel; Tumyan, Lusine; Schmolze, Daniel; Mortimer, Joanne; Rockne, Russell C.; Yankeelov, Thomas E. (2020). Towards integration of 64Cu-DOTA-trastuzumab PET-CT and MRI with mathematical modeling to predict response to neoadjuvant therapy in HER2 + breast cancer. Scientific reports, 10(1), p. 20518. Springer Nature 10.1038/s41598-020-77397-0
While targeted therapies exist for human epidermal growth factor receptor 2 positive (HER2 +) breast cancer, HER2 + patients do not always respond to therapy. We present the results of utilizing a biophysical mathematical model to predict tumor respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d692269c2e8a618712ec30483dae71