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Autor:
Lee, Ji Young, Lee, Kwang-sig, Seo, Bo Kyoung, Cho, Kyu Ran, Woo, Ok Hee, Song, Sung Eun, Kim, Eun-Kyung, Lee, Hye Yoon, Kim, Jung Sun, Cha, Jaehyung
Publikováno v:
European Radiology; Jan2022, Vol. 32 Issue 1, p650-660, 11p, 1 Black and White Photograph, 1 Diagram, 5 Charts, 1 Graph
Autor:
James L. Thorne, Melina C. Teske, Robyn V. Broad, Andrew M. Hanby, Laura M. Wastall, Stacey J. Jones, Thomas A. Hughes
Publikováno v:
British Journal of Cancer
Background Triple negative breast cancers (TNBC) have poor prognoses despite aggressive treatment with cytotoxic chemotherapy. Cancer-associated fibroblasts (CAFs) are prominent in tumour stroma. Our hypothesis was that CAFs modulate chemotherapy sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027115557c95f3f47f1ecb119dec9f3d
Autor:
Arja Jukkola-Vuorinen, Anniina Jääskeläinen, Kirsi-Maria Haapasaari, Päivi Auvinen, Ylermi Soini, Peeter Karihtala
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Background: The subtype of claudin-low breast cancer can be reliably determined only by gene-expression profiling. Attempts have been made to develop immunohistochemical surrogates, which nearly always focus on membranous claudin expression. Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0882fc6ea4b5d717997d116945eea4b4
http://urn.fi/urn:nbn:fi-fe201804196713
http://urn.fi/urn:nbn:fi-fe201804196713
Autor:
Andrzej Sygut, Julia Kruk-Jeromin, Ireneusz Majsterek, Adam Dziki, Grażyna Pasz-Walczak, Jan Rykała, Karolina Przybyłowska
Publikováno v:
Pathology Oncology Research
Tumoural angiogenesis is essential for the growth and spread of breast cancer cells. Therefore the aim of this study was to assess the diagnostic performance of angiogenesis markers in tumours and there reflecting levels in serum of breast cancer pat
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background The human Y-box-binding protein 1 (YB-1) is a member of the DNA/RNA-binding family of proteins that regulates transcription and translation of genes. Previous studies suggest that YB-1 may have an oncogenic role in various cancers. In this
Autor:
Pawel Jozwiak, Anna Krzeslak, Hanna Romanowicz, Katarzyna Wójcik-Krowiranda, Ewa Forma, Andrzej Bieńkiewicz, Magdalena Brys
Publikováno v:
Pathology Oncology Research
Cancer cells have accelerated metabolism and high glucose requirements. The up-regulation of specific glucose transporters may represent a key mechanism by which malignant cells may achieve increased glucose uptake to support the high rate of glycoly
Autor:
Mark Laible, Päivi Auvinen, Sebastian Eidt, Harri Sihto, Heikki Joensuu, Taina Turpeenniemi-Hujanen, Ugur Sahin, Sirkku Jyrkkiö, Kornelia Schlombs, Ralph M. Wirtz, Stefan Weber, Pirkko-Liisa Kellokumpu-Lehtinen, Sotiris Lakis, Jorma Isola, Päivi Heikkilä
Publikováno v:
Breast Cancer Research and Treatment
The biological subtype of breast cancer influences the selection of systemic therapy. Distinction between luminal A and B cancers depends on consistent assessment of Ki-67, but substantial intra-observer and inter-observer variability exists when imm
Autor:
Lisette Stork-Sloots, Paul Richards, Stephanie Akbari, Femke A. de Snoo, Mark A. Gittleman, Jennifer Beatty, Charles Nash, Laura A. Lee, Danielle Boselli, Angela Mislowsky, Mary Murray, James T. Symanowski, Peter D. Beitsch, Pat Whitworth, Paul L. Baron, James Pellicane
Publikováno v:
Annals of Surgical Oncology
Background The prospective Neoadjuvant Breast Symphony Trial (NBRST) study found that MammaPrint/BluePrint functional molecular subtype is superior to conventional immunohistochemistry/fluorescence in situ hybridization subtyping for predicting patho
Autor:
Robert A. Goldschmidt, Lisette Stork-Sloots, Massimo Cristofanilli, Jelle Wesseling, Katharine Yao, Mary Turk, Femke De Snoo
Publikováno v:
Breast Cancer Research and Treatment
Combined use of MammaPrint and a molecular subtyping profile (BluePrint) identifies disease subgroups with marked differences in long-term outcome and response to neo-adjuvant therapy. The aim of this study was to evaluate the prognostic value of mol
Fresh Surgical Specimens Yield Breast Stem/Progenitor Cells and Reveal Their Oncogenic Abnormalities
Autor:
Ariel L. Hernandez, Jennifer A. Murphy, Rodney F. Pommier, Juliana E. Hansen, Patrick Muller, Arpana Naik, Esther Han, John T. Vetto, Brian S. Diggs, Su Ellen J. Pommier, Kristen P. Massimino, Erin Chamberlain
Publikováno v:
Annals of Surgical Oncology
Background The process by which breast cancer stem cells arise is unknown. It may be that the benign stem cells in breast tissue are transformed into malignant stem cells through the acquisition of genetic abnormalities. In this study, we collected a