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of 61
pro vyhledávání: ''
Autor:
Waleed S. Al Amri, William E. Hughes, James L. Thorne, Geoff Wells, Ian M. Carr, Brian V Hogan, Thomas A. Hughes, Fiona Langlands, Arindam Pramanik, Layla K. Younis, Stacey J. Jones, Sarah A. Harris, Eldo T. Verghese, Rebecca Millican-Slater, Nevine M.F. El Deeb, Mervat A. Hamza, Baek Kim, Noha Gwili
Publikováno v:
British Journal of Cancer
Background Breast cancer stem cells (BCSCs) are drivers of therapy-resistance, therefore are responsible for poor survival. Molecular signatures of BCSCs from primary cancers remain undefined. Here, we identify the consistent transcriptome of primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a64defdd7881cec05092b3963a5ac9
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
Autor:
James L. Thorne, Melina C. Teske, Robyn V. Broad, Andrew M. Hanby, Laura M. Wastall, Stacey J. Jones, Thomas A. Hughes
Publikováno v:
British Journal of Cancer
Background Triple negative breast cancers (TNBC) have poor prognoses despite aggressive treatment with cytotoxic chemotherapy. Cancer-associated fibroblasts (CAFs) are prominent in tumour stroma. Our hypothesis was that CAFs modulate chemotherapy sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027115557c95f3f47f1ecb119dec9f3d
Autor:
Miguel Gil-Gil, José A. García-Sáenz, E Dalmau Portulas, Elena García-Martínez, Nuria Ribelles, A. Santaballa Bertran, E. Martínez de Dueñas, I Alvarez-Lopez, Susana Bezares
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Clinical & Translational Oncology
Universidad de Barcelona
Clinical & Translational Oncology
PurposeHormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) requires a therapeutic approach that takes into account multiple factors, with treatment being based on anti-estrogen hormo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a263cb82f360402dddafab187eefb
http://hdl.handle.net/2445/174389
http://hdl.handle.net/2445/174389
Autor:
Arja Jukkola-Vuorinen, Anniina Jääskeläinen, Kirsi-Maria Haapasaari, Päivi Auvinen, Ylermi Soini, Peeter Karihtala
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Background: The subtype of claudin-low breast cancer can be reliably determined only by gene-expression profiling. Attempts have been made to develop immunohistochemical surrogates, which nearly always focus on membranous claudin expression. Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0882fc6ea4b5d717997d116945eea4b4
http://urn.fi/urn:nbn:fi-fe201804196713
http://urn.fi/urn:nbn:fi-fe201804196713
Autor:
Cecilia Gelfi, Luigi Minafra, Valentina Bravatà, Rossana Norata, Carmelo Lupo, Massimo Viola, Cristina Messa
Publikováno v:
BMC research notes 5 (2012): 343. doi:10.1186/1756-0500-5-343
info:cnr-pdr/source/autori:Luigi Minafra; Rossana Norata; Valentina Bravatà; Massimo Viola; Carmelo Lupo; Cecilia Gelfi; Cristina Messa./titolo:Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report./doi:10.1186%2F1756-0500-5-343/rivista:BMC research notes/anno:2012/pagina_da:343/pagina_a:/intervallo_pagine:343/volume:5
BMC Research Notes
BMC Research Notes, Vol 5, Iss 1, p 343 (2012)
info:cnr-pdr/source/autori:Luigi Minafra; Rossana Norata; Valentina Bravatà; Massimo Viola; Carmelo Lupo; Cecilia Gelfi; Cristina Messa./titolo:Unmasking epithelial-mesenchymal transition in a breast cancer primary culture: a study report./doi:10.1186%2F1756-0500-5-343/rivista:BMC research notes/anno:2012/pagina_da:343/pagina_a:/intervallo_pagine:343/volume:5
BMC Research Notes
BMC Research Notes, Vol 5, Iss 1, p 343 (2012)
Background Immortalized cancer cell lines are now well-established procedures in biomedicine for a more complete understanding of cellular processes in cancer. However, they are more useful in preparation of fresh tumour tissue, in order to obtain ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879cc7aa8288ebe6181e5c13b2617698
http://hdl.handle.net/10281/37353
http://hdl.handle.net/10281/37353
Autor:
Mark Laible, Päivi Auvinen, Sebastian Eidt, Harri Sihto, Heikki Joensuu, Taina Turpeenniemi-Hujanen, Ugur Sahin, Sirkku Jyrkkiö, Kornelia Schlombs, Ralph M. Wirtz, Stefan Weber, Pirkko-Liisa Kellokumpu-Lehtinen, Sotiris Lakis, Jorma Isola, Päivi Heikkilä
Publikováno v:
Breast Cancer Research and Treatment
The biological subtype of breast cancer influences the selection of systemic therapy. Distinction between luminal A and B cancers depends on consistent assessment of Ki-67, but substantial intra-observer and inter-observer variability exists when imm
Autor:
Wilma L. Lingle, Beiyun Chen, Michael F. Press, Howard M. Stern, Monica M. Reinholz, Mona Shing, Edith A. Perez, Robert B. Jenkins, Amylou C. Dueck, Soonmyung Paik, Reid G. Meyer, Melanie Finnigan, Marc Buyse, JoAnne Zujewski, Ivonne Villalobos, Dennis J. Slamon, Chungyeul Kim, Anne E. Wiktor
Publikováno v:
Breast Cancer Research and Treatment
A comprehensive, blinded, pathology evaluation of HER2 testing in HER2-positive/negative breast cancers was performed among three central laboratories. Immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) analyses were performed o
Autor:
Marc J. van de Vijver, Gerrit K. J. Hooijer, Hugo M. Horlings, Jelle Wesseling, Hans Halfwerk, C. Dilara Savci-Heijink
Publikováno v:
Breast Cancer Research and Treatment
Breast cancer research and treatment, 150(3), 547-557. Springer New York
Breast cancer research and treatment, 150(3), 547-557. Springer New York
Among breast cancer patients who develop distant metastases, there is marked variability in the clinical course, including metastasis pattern. Here, we present a retrospective study of breast cancer patients who all developed distant metastases focus
Autor:
Anna Glajcar, Joanna Szpor, Katarzyna Ewa Tyrak, Joanna Streb, Agnieszka Pacek, Krzysztof Okoń, Florence Chan, Diana Hodorowicz-Zaniewska
Publikováno v:
Virchows Archiv
Mast cells (MCs) are a part of the innate immune system. The MC functions toward cancer are partially based on the release of chymase and tryptase. However, the MC effect on breast cancer is controversial. The aim of our study was to investigate the
Autor:
Ana Lluch Hernandez, José Alejandro Pérez Fidalgo, José Ángel García Sáenz, Jose Ignacio Chacon Lopez-Muniz, Ángel Guerrero Zotano, Eduardo Martínez de Dueñas, María Helena López de Ceballos Reyna, Jaime Ferrer Lozano, Noelia Martínez Jañez, Silvia Antolín Novoa, Amparo Oltra Ferrando, Gustavo Catalan, Salomón Menjón, Ramon Maria Perez Carrion, Eva Carrasco Carrascal, Vicente Carañana Ballerini, Octavio Burgués Gasión, Antonio Antón Torres, Andrés Hernando Capilla, Isabel Blancas Lopez-Barajas, Montserrat Muñoz Mateu, Ana M. Gonzalez-Angulo, Ángela López Rodríguez
Publikováno v:
Breast Cancer Research and Treatment
The objective of this study was to determine the conversion rate of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER) and progesterone receptor (PR) between primary tumors and metastatic lesions in advanced breast cancer. Patien