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Publikováno v:
British Journal of Cancer
Background Some endogenous hormones have been associated with breast cancer risk, but the nature of these relationships is not fully understood. Methods UK Biobank was used. Hormone concentrations were measured in serum collected in 2006–2010, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d482614b3e60f0e3b3fcf0d952cf3d1b
https://ora.ox.ac.uk/objects/uuid:2298adb9-eb05-46ad-ae36-48abd7ac39d1
https://ora.ox.ac.uk/objects/uuid:2298adb9-eb05-46ad-ae36-48abd7ac39d1
Autor:
Michael S. Toss, Emad A. Rakha, Chitra Joseph, Padmashree C.G. Rida, Andrew R. Green, Ian O. Ellis, Nigel P. Mongan, Mohammed A. Aleskandarany, Ibrahim Alshankyty, Mansour Alsaleem, Sasagu Kurozumi, Angela Ogden, Ritu Aneja
E-cadherin is a tumor suppressor gene in invasive lobular breast cancer. However, a proportion of high-grade ductal carcinoma shows reduced/loss of E-cadherin. In this study, we assessed the underlying mechanisms and molecular implications of E-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4fd096ae4d5a4d6360edf9b34a9f20
https://clok.uclan.ac.uk/34530/1/34530.pdf
https://clok.uclan.ac.uk/34530/1/34530.pdf
Autor:
Zsuzsanna Varga, Thomas Ruhstaller, Ulrike Perriard, Dirk Klingbiel, Tilman T. Rau, Jean-Christophe Tille, Beat Thuerlimann, Hanne Hawle, Qiyu Li, Wolfram Jochum
Publikováno v:
Varga, Zsuzsanna; Li, Qiyu; Jochum, Wolfram; Perriard, Ulrike; Rau, Tilman; Tille, Jean-Christoph; Hawle, Hanne; Klingbiel, Dirk; Thuerlimann, Beat; Ruhstaller, Thomas (2019). Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort. Scientific reports, 9(1), p. 13534. Springer Nature 10.1038/s41598-019-49638-4
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol. 9, No 1 (2019) P. 13534
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol. 9, No 1 (2019) P. 13534
Scientific Reports
The assessment of Ki-67 in early-stage breast cancer has become an important diagnostic tool in planning adjuvant therapy, particularly for the administration of additional chemotherapy to hormone-responsive patients. An accurate determination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509ed0eb6c511bb431eb561f8c240921
Autor:
Arja Jukkola-Vuorinen, Anniina Jääskeläinen, Kirsi-Maria Haapasaari, Päivi Auvinen, Ylermi Soini, Peeter Karihtala
Publikováno v:
BMC Cancer
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Background: The subtype of claudin-low breast cancer can be reliably determined only by gene-expression profiling. Attempts have been made to develop immunohistochemical surrogates, which nearly always focus on membranous claudin expression. Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0882fc6ea4b5d717997d116945eea4b4
http://urn.fi/urn:nbn:fi-fe201804196713
http://urn.fi/urn:nbn:fi-fe201804196713
Autor:
Rezvan Esmaeili, Hassan Fazilaty, Ali-Akbar Zare, Mehrdad Asghari Estiar, Ali Zekri, Narges Jafarbeik-Iravani, Keivan Majidzadeh-A, Leila Farahmand
Carcinoembryonic antigen (CEA) family members play important roles in malignancies and are introduced as biomarkers in different types of cancers. Among them CEACAM19 (CEAL1) gene, a new member of the CEA family, remains to be fully elucidated. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1808b0df50460e3c4e3fc63b2eb78444
http://hdl.handle.net/10261/308379
http://hdl.handle.net/10261/308379
Autor:
Graham Ball, Jonathon Blake, Amanda Devaney, Aoife Lowery, Christophe Lemetre, Vladimir Benes, Sabine Schmidt, Roisin E McNeill, Nicola Miller, Pamela A Davoren, Michael J. Kerin
Publikováno v:
Breast Cancer Research : BCR
peer-reviewed Introduction Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the oestrogen, progesterone and HER2/ neu receptors which characterize clinically distinct breast tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d2ae9d83199bb46e19c5d330eaa7d0f
http://hdl.handle.net/10379/12508
http://hdl.handle.net/10379/12508
Autor:
Pawel Jozwiak, Anna Krzeslak, Hanna Romanowicz, Katarzyna Wójcik-Krowiranda, Ewa Forma, Andrzej Bieńkiewicz, Magdalena Brys
Publikováno v:
Pathology Oncology Research
Cancer cells have accelerated metabolism and high glucose requirements. The up-regulation of specific glucose transporters may represent a key mechanism by which malignant cells may achieve increased glucose uptake to support the high rate of glycoly
Autor:
Mark Laible, Päivi Auvinen, Sebastian Eidt, Harri Sihto, Heikki Joensuu, Taina Turpeenniemi-Hujanen, Ugur Sahin, Sirkku Jyrkkiö, Kornelia Schlombs, Ralph M. Wirtz, Stefan Weber, Pirkko-Liisa Kellokumpu-Lehtinen, Sotiris Lakis, Jorma Isola, Päivi Heikkilä
Publikováno v:
Breast Cancer Research and Treatment
The biological subtype of breast cancer influences the selection of systemic therapy. Distinction between luminal A and B cancers depends on consistent assessment of Ki-67, but substantial intra-observer and inter-observer variability exists when imm
Autor:
Sônia Nair Báo, Aparecido Ribeiro de Souza, Marcella Lemos Brettas Carneiro, Ana Luisa Miranda-Vilela, Raphael Cândido Apolinário Peixoto, Ricardo G. Oliveira, Matheus Oliveira da Silva, José de Souza Filho
Publikováno v:
Tumour Biology
Breast cancer is one of the most prevalent cancer types among women. The use of magnetic fluids for specific delivery of drugs represents an attractive platform for chemotherapy. In our previous studies, it was demonstrated that maghemite nanoparticl
Publikováno v:
Breast Cancer (Tokyo, Japan)
Background CacyBP/SIP (calcyclin binding protein/Siah-1 interacting protein) was originally discovered in Ehrlich ascities tumor cells but was later found also in many different tumors. Methods To better understand the function of CacyBP/SIP in carci