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Publikováno v:
Br J Cancer
NEAT1 is a highly abundant nuclear architectural long non-coding RNA. There are two overlapping NEAT1 isoforms, NEAT1_1 and NEAT1_2, of which the latter is an essential scaffold for the assembly of a class of nuclear ribonucleoprotein bodies called p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bde762ce063b40b9e2f9019c14773ac
https://hdl.handle.net/10037/24685
https://hdl.handle.net/10037/24685
Autor:
Waleed S. Al Amri, William E. Hughes, James L. Thorne, Geoff Wells, Ian M. Carr, Brian V Hogan, Thomas A. Hughes, Fiona Langlands, Arindam Pramanik, Layla K. Younis, Stacey J. Jones, Sarah A. Harris, Eldo T. Verghese, Rebecca Millican-Slater, Nevine M.F. El Deeb, Mervat A. Hamza, Baek Kim, Noha Gwili
Publikováno v:
British Journal of Cancer
Background Breast cancer stem cells (BCSCs) are drivers of therapy-resistance, therefore are responsible for poor survival. Molecular signatures of BCSCs from primary cancers remain undefined. Here, we identify the consistent transcriptome of primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a64defdd7881cec05092b3963a5ac9
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
Publikováno v:
British Journal of Cancer
Background Some endogenous hormones have been associated with breast cancer risk, but the nature of these relationships is not fully understood. Methods UK Biobank was used. Hormone concentrations were measured in serum collected in 2006–2010, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d482614b3e60f0e3b3fcf0d952cf3d1b
https://ora.ox.ac.uk/objects/uuid:2298adb9-eb05-46ad-ae36-48abd7ac39d1
https://ora.ox.ac.uk/objects/uuid:2298adb9-eb05-46ad-ae36-48abd7ac39d1
Autor:
James L. Thorne, Melina C. Teske, Robyn V. Broad, Andrew M. Hanby, Laura M. Wastall, Stacey J. Jones, Thomas A. Hughes
Publikováno v:
British Journal of Cancer
Background Triple negative breast cancers (TNBC) have poor prognoses despite aggressive treatment with cytotoxic chemotherapy. Cancer-associated fibroblasts (CAFs) are prominent in tumour stroma. Our hypothesis was that CAFs modulate chemotherapy sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027115557c95f3f47f1ecb119dec9f3d
Autor:
Hege Edvarsen, Ana Lluch, Antonio Falcó, Laura J. van't Veer, Carlos Lozano-Asencio, Allan Balmain, Anne Lise Børresen-Dale, Joan Climent, Raimundo Cervera-Vidal, Vita Fedele, Rafa Tabares-Seisdedos, Irene Tadeo-Cervera, Sten Cornelissen, Jaume Forés-Martos, Julia Sierra-Roca, Marjanka Schmidt, Vessela N. Kristensen, Pilar Eroles, David A. Quigley
Publikováno v:
CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
NPJ breast cancer, vol 7, iss 1
Fundación Universitaria San Pablo CEU (FUSPCEU)
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
NPJ breast cancer, vol 7, iss 1
Polymorphisms in the PER3 gene have been associated with several human disease phenotypes, including sleep disorders and cancer. In particular, the long allele of a variable number of tandem repeat (VNTR) polymorphism has been previously linked to an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe28842d1952d5013093a97ab6d336f5
https://doi.org/10.1038/s41523-021-00329-2
https://doi.org/10.1038/s41523-021-00329-2
Autor:
Elise Klæstad, Signe Opdahl, Monica J. Engstrøm, Elisabeth Wik, Borgny Ytterhus, Anna M. Bofin, Marit Valla
Publikováno v:
Breast Cancer Research and Treatment
Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy number change and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49102c4df90ac263d4c308ee2094e138
https://hdl.handle.net/11250/2672584
https://hdl.handle.net/11250/2672584
Autor:
Nelofar Nargis, Gunjan Mandal, Samir Jana, Thomas A. Hughes, Soumya Chatterjee, Annesha Chatterjee, Laura M. Wastall, Himansu Roy, Arindam Bhattacharyya
Publikováno v:
British Journal of Cancer
BACKGROUND: Cancer-associated fibroblasts (CAFs) are known to impact on tumour behaviour, but the mechanisms controlling this are poorly understood. METHODS: Breast normal fibroblasts (NFs) or CAFs were isolated from cancers by laser microdissection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957384df57b4414e3eef66fa38c6c18b
https://eprints.whiterose.ac.uk/149993/8/s41416-019-0566-7.pdf
https://eprints.whiterose.ac.uk/149993/8/s41416-019-0566-7.pdf
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
[Background] Current therapeutic strategies that are used to combat breast cancer vary widely and largely depend on its clinicopathological features, including tumor subtype, size, stage, lymph node involvement, the presence of hormone receptors and/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6f37dcbb5ea82449e8289a41c8b7ba
http://hdl.handle.net/10261/201673
http://hdl.handle.net/10261/201673
Autor:
Zsuzsanna Varga, Thomas Ruhstaller, Ulrike Perriard, Dirk Klingbiel, Tilman T. Rau, Jean-Christophe Tille, Beat Thuerlimann, Hanne Hawle, Qiyu Li, Wolfram Jochum
Publikováno v:
Varga, Zsuzsanna; Li, Qiyu; Jochum, Wolfram; Perriard, Ulrike; Rau, Tilman; Tille, Jean-Christoph; Hawle, Hanne; Klingbiel, Dirk; Thuerlimann, Beat; Ruhstaller, Thomas (2019). Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort. Scientific reports, 9(1), p. 13534. Springer Nature 10.1038/s41598-019-49638-4
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol. 9, No 1 (2019) P. 13534
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol. 9, No 1 (2019) P. 13534
Scientific Reports
The assessment of Ki-67 in early-stage breast cancer has become an important diagnostic tool in planning adjuvant therapy, particularly for the administration of additional chemotherapy to hormone-responsive patients. An accurate determination of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509ed0eb6c511bb431eb561f8c240921
Autor:
María Teresa Sánchez-Barrón, Ana I. Álvarez-Mercado, Carmen M Ruiz-Marín, Cándido Robles-Sánchez, Saturnino Reyes Lartategui, María José Sáez-Lara, María Belén Sánchez-Andujar, Mariana F. Fernández, Alejandro J. Pérez-Alonso, Ana Moreno-Delgado, Tania Gallart-Aragón, Natalia Chueca, Katia Torres-Martínez, Julio Plaza-Díaz, Federico García, Iris Reina-Pérez, Luis Fontana, Pablo Torné
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
instname
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Cancer
instname
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Cancer
We would like to thank M Luisa Puertas-Martin and Isabel Manzano-Jimenez, nurses at the Unit of Mammary Pathology, General Surgery Service, San Cecilio University Hospital (Granada), without whose enthusiasm the enrolment of participants in Granada w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8509963333b0ca31ea8159ad28a282