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Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
© The Author(s), under exclusive licence to Springer Nature B.V. 2021
Breast cancer is a heterogeneous disease, which is the most common malignancy in women. The incidence and mortality rates of breast cancer indicate that it is the leading cau
Breast cancer is a heterogeneous disease, which is the most common malignancy in women. The incidence and mortality rates of breast cancer indicate that it is the leading cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f8704585dfee30fde57fafbb3e3a01
https://hdl.handle.net/10451/47138
https://hdl.handle.net/10451/47138
Autor:
Elise Klæstad, Signe Opdahl, Monica J. Engstrøm, Elisabeth Wik, Borgny Ytterhus, Anna M. Bofin, Marit Valla
Publikováno v:
Breast Cancer Research and Treatment
Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy number change and molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49102c4df90ac263d4c308ee2094e138
https://hdl.handle.net/11250/2672584
https://hdl.handle.net/11250/2672584
Autor:
Eitan Amir, Laura Díez-González, Alberto Ocaña, Arnoud J. Templeton, Bostjan Seruga, Verónica Sánchez-Corrales, Javier Pérez-Peña, Atanasio Pandiella
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Protein kinases are important components in oncogenic transformation of breast cancer. Evaluation of upregulated genes that codify for protein kinases could be used as biomarkers to predict clinical outcome. Gene expression and functional analyses us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10459b329187578640b5c7540f30ee2b
http://hdl.handle.net/10261/168766
http://hdl.handle.net/10261/168766
Autor:
A. Mc Cann, O. Mc Cormack, A Mc Goldrick, Michael J. Kerin, F. J. Cooke, Patricia Fitzpatrick, B. Flynn, Peter A. Dervan, Michele Harrison, Wen Y. Chung, E. Gallagher, Edward J. Fox
Publikováno v:
British Journal of Cancer
Growth arrest- specific gene 6 ( Gas6), identified in 1995, acts as the ligand to the Axl/ Tyro3 family of tyrosine kinase receptors and exerts mitogenic activity when bound to these receptors. Overexpression of the Axl/ Tyro3 receptor family has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed01896775f03c49259bece5931e206
http://hdl.handle.net/10379/12693
http://hdl.handle.net/10379/12693
Publikováno v:
Pathology Oncology Research
Breast invasive micropapillary carcinoma (IMPC) is a rare subtype of breast cancer with a high potential of lymph node metastasis, aggressive clinical behavior, and poor disease-free or overall survival. Expression of leucine zipper putative tumor su
Autor:
Mel Fox, Gary C. Starling, Mian Su, Sonia Tanlimco, Debra Chao, Shiming Ye, Donghee Choi, Johnny Yin, Lisa Durkin, Patricia Culp, Yongke Zhang, Eric D. Hsi, Mien Sho, Han Kim
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background The receptor for the cytokine TWEAK (TweakR) is a cell surface member of the tumor necrosis factor receptor superfamily with diverse biological roles. TNFRSF family members are appealing therapeutic targets in oncology due to their aberran
Autor:
Weiwei Nie, Chen-Yu Zhang, Xi Chen, Minghui Cao, Dongxia Hou, Ke Zen, Xiaohong Jiang, Xiaoxiang Guan, Xin Yan, Yujing Zhang, Jing Li
Publikováno v:
Protein & Cell
MicroRNAs (miRNAs) are small, non-coding RNAs that function as post-transcriptional regulators of gene expression. The deregulated expression of miRNAs is associated with a variety of diseases, including breast cancer. In the present study, we found
Autor:
Marie K. Kirby, Jason Gertz, Amy S. Nesmith, William E. Grizzle, Nicholas S. Davis, Patsy G. Oliver, Kevin M. Bowling, Katherine E. Varley, Albert F. LoBuglio, Richard M. Myers, Brian S. Roberts, Andres Forero, Donald J. Buchsbaum
Publikováno v:
Breast Cancer Research and Treatment
Read-through fusion transcripts that result from the splicing of two adjacent genes in the same coding orientation are a recently discovered type of chimeric RNA. We sought to determine if read-through fusion transcripts exist in breast cancer. We pe
Autor:
Marcia Batista Salzgeber, T. T Benvenuti, João Carlos Sampaio Góes, Maria Lucia Hirata Katayama, Maria Aparecida Azevedo Koike Folgueira, Paulo Roberto Del Valle, Jane Haruko Lima Kaiano, Rosângela Portilho Costa Santos, Suzana Terumi Honda, Dirce Maria Carraro, Patricia Bortman Rozenchan, E. C. Lyra, Maria Mitzi Brentani, Cesar Torres, Helena Brentani
Publikováno v:
Tumour Biology
Our aim was to evaluate the interaction between breast cancer cells and nodal fibroblasts, by means of their gene expression profile. Fibroblast primary cultures were established from negative and positive lymph nodes from breast cancer patients and
Autor:
Timothy P. Fleming, Sreeraj G. Pillai, Rebecca Aft, Mark A. Watson, Chidananda M. Siddappa, Kathryn Trinkaus, Nupur Dasgupta
Publikováno v:
Breast Cancer Research and Treatment
The presence of disseminated tumor cells (DTCs) in the bone marrow (BM) of breast cancer patients is prognostic for early relapse. In the present study, we analyzed the gene expression profiles from BM cells of breast cancer patients to identify mole