Zobrazeno 1 - 10
of 73
pro vyhledávání: ''
Autor:
Yan Zhang, Gang Wei, Yingmeng Ni, Yue Lu, Bin Li, Dan Li, Song Guo Zheng, Fuxiang Zhu, Ruihong Zhu, Zhijun Han, Qibin Leng, Yangyang Li, Shuaiwei Wang, Rui Liang, Guochao Shi, Andy Tsun, Haikun Wang, Hong-Xi Xu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications
FOXP3+ Regulatory T (Treg) cells play a key role in the maintenance of immune homeostasis and tolerance. Disruption of Foxp3 expression results in the generation of instable Treg cells and acquisition of effector T-cell-like function. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::621ad2a5ee15b3c340bde12f4513c3f3
https://ora.ox.ac.uk/objects/uuid:1996d6b4-b2cc-4777-97ca-3e329d01e6bb
https://ora.ox.ac.uk/objects/uuid:1996d6b4-b2cc-4777-97ca-3e329d01e6bb
Autor:
Patricia L. Lockwood, Matthew F. S. Rushworth, Luke Priestley, Nima Khalighinejad, Neil Garrett
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
The decision that it is worth doing something rather than nothing is a core yet understudied feature of voluntary behaviour. Here we study “willingness to act”, the probability of making a response given the context. Human volunteers encountered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c58c9de4a9d4d3eba70875da5655d0
https://ora.ox.ac.uk/objects/uuid:26b443d2-3833-4d65-9d75-f3de5d2d3080
https://ora.ox.ac.uk/objects/uuid:26b443d2-3833-4d65-9d75-f3de5d2d3080
Autor:
Juli Pausas, Vinícius Dantas
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Nature Communications
Nature Communications
Large mammal herbivores are important drivers of plant evolution and vegetation patterns, but the extent to which plant trait and ecosystem geography currently reflect the historical distribution of extinct megafauna is unknown. We address this quest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09784fbfe94f808945cafa2cce47233
http://hdl.handle.net/10261/284567
http://hdl.handle.net/10261/284567
Autor:
Ifat Geron, Angela Maria Savino, Hila Fishman, Noa Tal, John Brown, Virginia A. Turati, Chela James, Jolanda Sarno, Michal Hameiri-Grossman, Yu Nee Lee, Avigail Rein, Hillary Maniriho, Yehudit Birger, Anna Zemlyansky, Inna Muler, Kara L. Davis, Victoria Marcu-Malina, Nicole Mattson, Oren Parnas, Rabea Wagener, Ute Fischer, João T. Barata, Catriona H. M. Jamieson, Markus Müschen, Chun-Wei Chen, Arndt Borkhardt, Ilan Richard Kirsch, Arnon Nagler, Tariq Enver, Shai Izraeli
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38002787fba778c873bf64c9583e8b55
https://hdl.handle.net/10451/51189
https://hdl.handle.net/10451/51189
Autor:
Kristina Zec, Roman Fischer, Irina A. Udalova, Tariq E. Khoyratty, Claire Pearson, Hayley L. Eames, Benedikt M. Kessler, Hannah Almuttaqi, Grigory Ryzhakov, Simon Travis, Samuel J. Bullers, Luke Jostins-Dean, Alastair L. Corbin, Sarah Bonham, Zhichao Ai, Dorothée L. Berthold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Interferon regulating factor 5 (IRF5) is a multifunctional regulator of immune responses, and has a key pathogenic function in gut inflammation, but how IRF5 is modulated is still unclear. Having performed a kinase inhibitor library screening in macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e8cfb57ebeee917922ddd5935776e62
https://doi.org/10.1038/s41467-021-27038-5
https://doi.org/10.1038/s41467-021-27038-5
Autor:
Martín-Alonso, Mara, Iqbal, Sharif, Vornewald, Pia M., Lindholm, Håvard T., Damen, Mirjam J., Martínez, Fernando, Hoel, Sigrid, Díez-Sánchez, Alberto, Altelaar, Maarten, Katajisto, Pekka, Arroyo, Alicia G., Oudhoff, Menno J., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
17 p.-8 fig.
Smooth muscle is an essential component of the intestine, both to maintain its structure and produce peristaltic and segmentation movements. However, very little is known about other putative roles that smooth muscle cells may have.
Smooth muscle is an essential component of the intestine, both to maintain its structure and produce peristaltic and segmentation movements. However, very little is known about other putative roles that smooth muscle cells may have.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b98826dca588121db8a83fd6e3dd47
http://hdl.handle.net/10261/256789
http://hdl.handle.net/10261/256789
Autor:
Robert E MacLaren, Harry O Orlans, Michelle E. McClements, Alun R. Barnard, Cristina Martinez-Fernandez de la Camara
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Rhodopsin (RHO) gene mutations are a common cause of autosomal dominant retinitis pigmentosa (ADRP). The need to suppress toxic protein expression together with mutational heterogeneity pose challenges for treatment development. Mirtrons are atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d763a884a5b2e72b00d42ebcc5cfa5
https://ora.ox.ac.uk/objects/uuid:d5255281-048a-4e08-ac4a-f0defc618a77
https://ora.ox.ac.uk/objects/uuid:d5255281-048a-4e08-ac4a-f0defc618a77
Autor:
Anders Moen, Jesper V. Olsen, Lisa Schroer, Ida A. Grønsberg, Niels Eijkelkamp, Albert Jeltsch, Takehiro Suzuki, Tadahiro Shimazu, Naoshi Dohmae, Erna Davydova, Mikiko Sodeoka, Valentina Siino, Mai Akakabe, Jędrzej Małecki, Pål Ø. Falnes, Michael A. McDonough, Takashi Umehara, Yoshihiro Sohtome, Magnus E. Jakobsson, Angela Ho, Rita Pinto, Masaki Kikuchi, Sara Weirich, Christopher J. Schofield, Yoichi Shinkai, Hanneke L.D.M. Willemen, Maren Kirstin Schuhmacher, Tongri Liu
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Davydova, E, Shimazu, T, Schuhmacher, M K, Jakobsson, M E, Willemen, H L D M, Liu, T, Moen, A, Ho, A Y Y, Małecki, J, Schroer, L, Pinto, R, Suzuki, T, Grønsberg, I A, Sohtome, Y, Akakabe, M, Weirich, S, Kikuchi, M, Olsen, J V, Dohmae, N, Umehara, T, Sodeoka, M, Siino, V, McDonough, M A, Eijkelkamp, N, Schofield, C J, Jeltsch, A, Shinkai, Y & Falnes, P 2021, ' The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes ', Nature Communications, vol. 12, 891 . https://doi.org/10.1038/s41467-020-20670-7
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Davydova, E, Shimazu, T, Schuhmacher, M K, Jakobsson, M E, Willemen, H L D M, Liu, T, Moen, A, Ho, A Y Y, Małecki, J, Schroer, L, Pinto, R, Suzuki, T, Grønsberg, I A, Sohtome, Y, Akakabe, M, Weirich, S, Kikuchi, M, Olsen, J V, Dohmae, N, Umehara, T, Sodeoka, M, Siino, V, McDonough, M A, Eijkelkamp, N, Schofield, C J, Jeltsch, A, Shinkai, Y & Falnes, P 2021, ' The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes ', Nature Communications, vol. 12, 891 . https://doi.org/10.1038/s41467-020-20670-7
Post-translational methylation plays a crucial role in regulating and optimizing protein function. Protein histidine methylation, occurring as the two isomers 1- and 3-methylhistidine (1MH and 3MH), was first reported five decades ago, but remains la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8df554296bacb78fc88ad2f9d35057
https://ora.ox.ac.uk/objects/uuid:5d2edc4d-b490-4789-a8f9-e3a23c7392d4
https://ora.ox.ac.uk/objects/uuid:5d2edc4d-b490-4789-a8f9-e3a23c7392d4
Publikováno v:
Sharma, Puneet; Wu, Jie; Nilges, Benedikt S.; Leidel, Sebastian A. (2021). Humans and other commonly used model organisms are resistant to cycloheximide-mediated biases in ribosome profiling experiments. Nature Communications, 12(1), p. 5094. Springer Nature 10.1038/s41467-021-25411-y
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Ribosome profiling measures genome-wide translation dynamics at sub-codon resolution. Cycloheximide (CHX), a widely used translation inhibitor to arrest ribosomes in these experiments, has been shown to induce biases in yeast, questioning its use. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dea5cae60549e3ad89cdfae2553dc5c
https://boris.unibe.ch/160036/1/NATURE_COMMUNICATIONS_2021_.pdf
https://boris.unibe.ch/160036/1/NATURE_COMMUNICATIONS_2021_.pdf
Autor:
Yun-Ru Chen, Lee-Way Jin, Yu Sheng Fang, Yao Hsiang Shih, Ling Hsien Tu, Wei Wei Chang, Yeh Tung Lin, Kiruthika Ganesan, Pao Sheng Chang, Ting Yu Chang
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
TDP-43 inclusions are found in many Alzheimer’s disease (AD) patients presenting faster disease progression and greater brain atrophy. Previously, we showed full-length TDP-43 forms spherical oligomers and perturbs amyloid-β (Aβ) fibrillization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4187131f111a6378df3c13344a8d36c5
https://ora.ox.ac.uk/objects/uuid:fb36f9aa-6fd0-4b55-b6a0-09c5d1ec070c
https://ora.ox.ac.uk/objects/uuid:fb36f9aa-6fd0-4b55-b6a0-09c5d1ec070c